9 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CALM1	Calmodulin 1; Belongs to the calmodulin family. (150 aa)
	LOC105614854	Uncharacterized protein; Belongs to the calmodulin family. (145 aa)
	PDE1A	Phosphodiesterase. (514 aa)
	PDE1B	Phosphodiesterase. (535 aa)
	CALM3	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). (149 aa)
	W5PG97_SHEEP	Uncharacterized protein. (143 aa)
	W5PF10_SHEEP	Uncharacterized protein. (72 aa)
	PDE1C	Phosphodiesterase. (657 aa)
	ENSOARP00000005690	annotation not available (148 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALM3	ENSOARP00000005690	ENSOARP00000011414	ENSOARP00000005690	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	annotation not available	0.847
CALM3	LOC105614854	ENSOARP00000011414	ENSOARP00000022802	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Uncharacterized protein; Belongs to the calmodulin family.	0.949
CALM3	PDE1A	ENSOARP00000011414	ENSOARP00000018050	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Phosphodiesterase.	0.968
CALM3	PDE1B	ENSOARP00000011414	ENSOARP00000017297	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Phosphodiesterase.	0.960
CALM3	PDE1C	ENSOARP00000011414	ENSOARP00000007610	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Phosphodiesterase.	0.952
ENSOARP00000005690	CALM3	ENSOARP00000005690	ENSOARP00000011414	annotation not available	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	0.847
ENSOARP00000005690	PDE1A	ENSOARP00000005690	ENSOARP00000018050	annotation not available	Phosphodiesterase.	0.534
LOC105614854	CALM3	ENSOARP00000022802	ENSOARP00000011414	Uncharacterized protein; Belongs to the calmodulin family.	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	0.949
LOC105614854	PDE1A	ENSOARP00000022802	ENSOARP00000018050	Uncharacterized protein; Belongs to the calmodulin family.	Phosphodiesterase.	0.962
LOC105614854	PDE1B	ENSOARP00000022802	ENSOARP00000017297	Uncharacterized protein; Belongs to the calmodulin family.	Phosphodiesterase.	0.960
LOC105614854	PDE1C	ENSOARP00000022802	ENSOARP00000007610	Uncharacterized protein; Belongs to the calmodulin family.	Phosphodiesterase.	0.953
PDE1A	CALM3	ENSOARP00000018050	ENSOARP00000011414	Phosphodiesterase.	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	0.968
PDE1A	ENSOARP00000005690	ENSOARP00000018050	ENSOARP00000005690	Phosphodiesterase.	annotation not available	0.534
PDE1A	LOC105614854	ENSOARP00000018050	ENSOARP00000022802	Phosphodiesterase.	Uncharacterized protein; Belongs to the calmodulin family.	0.962
PDE1A	PDE1B	ENSOARP00000018050	ENSOARP00000017297	Phosphodiesterase.	Phosphodiesterase.	0.980
PDE1A	PDE1C	ENSOARP00000018050	ENSOARP00000007610	Phosphodiesterase.	Phosphodiesterase.	0.942
PDE1A	W5PF10_SHEEP	ENSOARP00000018050	ENSOARP00000009025	Phosphodiesterase.	Uncharacterized protein.	0.428
PDE1B	CALM3	ENSOARP00000017297	ENSOARP00000011414	Phosphodiesterase.	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	0.960
PDE1B	LOC105614854	ENSOARP00000017297	ENSOARP00000022802	Phosphodiesterase.	Uncharacterized protein; Belongs to the calmodulin family.	0.960
PDE1B	PDE1A	ENSOARP00000017297	ENSOARP00000018050	Phosphodiesterase.	Phosphodiesterase.	0.980