69 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACR	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. (416 aa)
	ADAM21	ADAM metallopeptidase domain 21. (718 aa)
	W5NSU1_SHEEP	Hyaluronidase. (553 aa)
	W5NTB5_SHEEP	Hyaluronidase. (552 aa)
	CATSPER1	Cation channel sperm associated 1. (699 aa)
	MLH3	MutL homolog 3. (1485 aa)
	ADAM32	ADAM metallopeptidase domain 32. (636 aa)
	W5NV82_SHEEP	Uncharacterized protein. (810 aa)
	ADAM2	ADAM metallopeptidase domain 2. (741 aa)
	W5NVP8_SHEEP	Pep_M12B_propep domain-containing protein. (169 aa)
	ADAM18	ADAM metallopeptidase domain 18. (743 aa)
	PSMC3IP	PSMC3 interacting protein. (217 aa)
	MND1	Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (204 aa)
	SYNE1	Spectrin repeat containing nuclear envelope protein 1. (8803 aa)
	ZP4	Zona pellucida glycoprotein 4. (540 aa)
	CATSPERB	Cation channel sperm associated auxiliary subunit beta. (1109 aa)
	IZUMO1	Izumo-Ig domain-containing protein. (335 aa)
	LOC101112695	Uncharacterized protein. (711 aa)
	DIDO1	Death inducer-obliterator 1. (2069 aa)
	TEX15	Testis expressed 15, meiosis and synapsis associated. (3179 aa)
	W5NPV3_SHEEP	Disintegrin domain-containing protein. (190 aa)
	KCNU1	Potassium calcium-activated channel subfamily U member 1. (1141 aa)
	W5NR72_SHEEP	Pep_M12B_propep domain-containing protein. (95 aa)
	TMEM238L	Transmembrane protein 238 like. (79 aa)
	CATSPER4	Cation channel sperm associated 4. (468 aa)
	W5P5E4_SHEEP	DNA_MISMATCH_REPAIR_2 domain-containing protein. (835 aa)
	SUN5	Sad1 and UNC84 domain containing 5. (380 aa)
	CATSPERG	Cation channel sperm associated auxiliary subunit gamma. (1120 aa)
	SUN1	Sad1 and UNC84 domain containing 1. (814 aa)
	ADAM20	ADAM metallopeptidase domain 20. (744 aa)
	SYNE2	Spectrin repeat containing nuclear envelope protein 2. (6879 aa)
	W5QGT8_SHEEP	Uncharacterized protein. (715 aa)
	SYCP1	Synaptonemal complex protein 1. (1000 aa)
	FAM107B	Uncharacterized protein. (154 aa)
	CATSPERD	Cation channel sperm associated auxiliary subunit delta. (781 aa)
	W5PD97_SHEEP	Uncharacterized protein. (436 aa)
	CD9	Tetraspanin. (219 aa)
	KCNT2	Potassium sodium-activated channel subfamily T member 2. (1086 aa)
	LOC101111693	Uncharacterized protein. (752 aa)
	ADAM29	ADAM metallopeptidase domain 29. (725 aa)
	B4GALT1	Uncharacterized protein. (402 aa)
	SYCE2	Synaptonemal complex central element protein 2. (184 aa)
	CATSPER2	Cation channel sperm associated 2. (538 aa)
	LOC101112445	Uncharacterized protein. (713 aa)
	MSH4	MutS homolog 4. (935 aa)
	FKBP6	Peptidylprolyl isomerase. (331 aa)
	SYCE1	Synaptonemal complex central element protein 1. (323 aa)
	IZUMO2	KRAB domain-containing protein. (199 aa)
	ZP3	ZP domain-containing protein. (408 aa)
	SPAG4	Sperm associated antigen 4. (440 aa)
	ZP2	Zona pellucida glycoprotein 2. (714 aa)
	IZUMO3	IZUMO family member 3. (240 aa)
	CATSPER3	Cation channel sperm associated 3. (400 aa)
	IZUMO4	IZUMO family member 4. (201 aa)
	SYCP2L	Synaptonemal complex protein 2 like. (856 aa)
	SYCP3	Synaptonemal complex protein 3. (225 aa)
	LOC101111942	Uncharacterized protein. (739 aa)
	SYCP2	Synaptonemal complex protein 2. (1260 aa)
	DMC1	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (342 aa)
	SUN2	Sad1 and UNC84 domain containing 2. (804 aa)
	SUN3	Sad1 and UNC84 domain containing 3. (359 aa)
	STAG3	Stromal antigen 3. (1275 aa)
	HVCN1	Hydrogen voltage gated channel 1. (270 aa)
	W5Q8C3_SHEEP	Uncharacterized protein. (722 aa)
	SPO11	SPO11 initiator of meiotic double stranded breaks. (395 aa)
	W5QBL3_SHEEP	Uncharacterized protein. (403 aa)
	REC8	REC8 meiotic recombination protein. (592 aa)
	SMC1B	Structural maintenance of chromosomes protein. (1235 aa)
	SYCE3	Synaptonemal complex central element protein 3. (87 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACR	CD9	ENSOARP00000021514	ENSOARP00000009233	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	Tetraspanin.	0.452
ACR	IZUMO1	ENSOARP00000021514	ENSOARP00000013009	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	Izumo-Ig domain-containing protein.	0.676
ACR	IZUMO4	ENSOARP00000021514	ENSOARP00000015638	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	IZUMO family member 4.	0.562
ACR	SPO11	ENSOARP00000021514	ENSOARP00000019324	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	SPO11 initiator of meiotic double stranded breaks.	0.407
ACR	SYCP1	ENSOARP00000021514	ENSOARP00000021568	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	Synaptonemal complex protein 1.	0.524
ACR	SYCP3	ENSOARP00000021514	ENSOARP00000016365	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	Synaptonemal complex protein 3.	0.602
ACR	W5NSU1_SHEEP	ENSOARP00000021514	ENSOARP00000001231	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	Hyaluronidase.	0.644
ACR	W5NTB5_SHEEP	ENSOARP00000021514	ENSOARP00000001406	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	Hyaluronidase.	0.516
ACR	ZP2	ENSOARP00000021514	ENSOARP00000015528	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	Zona pellucida glycoprotein 2.	0.583
ADAM2	ADAM20	ENSOARP00000002216	ENSOARP00000022780	ADAM metallopeptidase domain 2.	ADAM metallopeptidase domain 20.	0.795
ADAM2	ADAM21	ENSOARP00000002216	ENSOARP00000001107	ADAM metallopeptidase domain 2.	ADAM metallopeptidase domain 21.	0.804
ADAM2	B4GALT1	ENSOARP00000002216	ENSOARP00000010241	ADAM metallopeptidase domain 2.	Uncharacterized protein.	0.549
ADAM2	CATSPER1	ENSOARP00000002216	ENSOARP00000001567	ADAM metallopeptidase domain 2.	Cation channel sperm associated 1.	0.507
ADAM2	CATSPER2	ENSOARP00000002216	ENSOARP00000011634	ADAM metallopeptidase domain 2.	Cation channel sperm associated 2.	0.613
ADAM2	IZUMO1	ENSOARP00000002216	ENSOARP00000013009	ADAM metallopeptidase domain 2.	Izumo-Ig domain-containing protein.	0.626
ADAM2	IZUMO2	ENSOARP00000002216	ENSOARP00000014740	ADAM metallopeptidase domain 2.	KRAB domain-containing protein.	0.460
ADAM2	IZUMO3	ENSOARP00000002216	ENSOARP00000015546	ADAM metallopeptidase domain 2.	IZUMO family member 3.	0.460
ADAM2	IZUMO4	ENSOARP00000002216	ENSOARP00000015638	ADAM metallopeptidase domain 2.	IZUMO family member 4.	0.455
ADAM2	LOC101112445	ENSOARP00000002216	ENSOARP00000012720	ADAM metallopeptidase domain 2.	Uncharacterized protein.	0.751
ADAM2	LOC101112695	ENSOARP00000002216	ENSOARP00000012867	ADAM metallopeptidase domain 2.	Uncharacterized protein.	0.745