STRINGSTRING
FIGN FIGN SUMO1 SUMO1 LBR LBR W5Q6I1_SHEEP W5Q6I1_SHEEP WDR41 WDR41 CHMP2B CHMP2B FIGNL2 FIGNL2 NUP35 NUP35 TUBA3E TUBA3E TUBB1 TUBB1 NUP37 NUP37 RAN RAN W5Q039_SHEEP W5Q039_SHEEP ADGRD1 ADGRD1 RBM39 RBM39 UBE2I UBE2I CHMP4C CHMP4C W5PX40_SHEEP W5PX40_SHEEP CCNB3 CCNB3 ANKLE2 ANKLE2 CHMP7 CHMP7 NUP155 NUP155 LEMD2 LEMD2 RAN-2 RAN-2 C17orf75 C17orf75 SPAST SPAST NUP85 NUP85 SEC13 SEC13 ADGRB3 ADGRB3 W5PTP9_SHEEP W5PTP9_SHEEP W5PU38_SHEEP W5PU38_SHEEP LOC101114746 LOC101114746 LMNB2 LMNB2 TUBA8 TUBA8 W5P3V9_SHEEP W5P3V9_SHEEP CDK1 CDK1 CHMP2A CHMP2A IST1 IST1 W5P023_SHEEP W5P023_SHEEP IQCA1L IQCA1L KATNAL2 KATNAL2 PPP2R2B PPP2R2B AHCTF1 AHCTF1 NUP133 NUP133 LEMD3 LEMD3 RCC1 RCC1 NUP43 NUP43 W5NX37_SHEEP W5NX37_SHEEP NUP98 NUP98 ADGRB1 ADGRB1 W5NVI3_SHEEP W5NVI3_SHEEP VRK2 VRK2 W5NUI0_SHEEP W5NUI0_SHEEP BANF1 BANF1 ADGRB2 ADGRB2 RPGR RPGR CHMP6 CHMP6 NUP107 NUP107 W5NQ01_SHEEP W5NQ01_SHEEP VRK1 VRK1 TM9SF1 TM9SF1 RBM23 RBM23 TUBA4A TUBA4A LOC101116286 LOC101116286 LOC101107266 LOC101107266 CCNB2 CCNB2 W5QIP1_SHEEP W5QIP1_SHEEP W5QIZ8_SHEEP W5QIZ8_SHEEP CC2D1B CC2D1B LMNA LMNA W5P6X3_SHEEP W5P6X3_SHEEP SIRT2 SIRT2 CNTD2 CNTD2 NDC1 NDC1 VPS4A VPS4A ENSOARP00000007526 ENSOARP00000007526 CC2D1A CC2D1A NUP160 NUP160 FIGNL1 FIGNL1 NCOA5 NCOA5 KPNB1 KPNB1 CHMP4B CHMP4B NUP188 NUP188 NUP205 NUP205 TUBAL3 TUBAL3 PPP2R2A PPP2R2A EMD EMD MDP1 MDP1 IQCA1 IQCA1 W5QBU8_SHEEP W5QBU8_SHEEP NUP93 NUP93 W5QA93_SHEEP W5QA93_SHEEP LMNB1 LMNB1 RANGAP1 RANGAP1 BANF2 BANF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FIGNFidgetin, microtubule severing factor; Belongs to the AAA ATPase family. (759 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
LBRLamin B receptor. (622 aa)
W5Q6I1_SHEEPUncharacterized protein. (204 aa)
WDR41WD repeat domain 41. (459 aa)
CHMP2BCharged multivesicular body protein 2B. (213 aa)
FIGNL2Uncharacterized protein. (185 aa)
NUP35Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (327 aa)
TUBA3ETubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (380 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (424 aa)
NUP37Nucleoporin 37. (326 aa)
RANGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (205 aa)
W5Q039_SHEEPTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
ADGRD1Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family. (906 aa)
RBM39RNA binding motif protein 39. (525 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (216 aa)
CHMP4CCharged multivesicular body protein 4C. (236 aa)
W5PX40_SHEEPUncharacterized protein. (615 aa)
CCNB3Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (1301 aa)
ANKLE2Ankyrin repeat and LEM domain containing 2. (975 aa)
CHMP7Charged multivesicular body protein 7. (452 aa)
NUP155Nucleoporin 155. (1394 aa)
LEMD2LEM domain containing 2. (301 aa)
RAN-2GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
C17orf75Chromosome 17 open reading frame 75. (400 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (624 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (657 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (322 aa)
ADGRB3Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1237 aa)
W5PTP9_SHEEPUncharacterized protein; Belongs to the cyclin family. (403 aa)
W5PU38_SHEEPUbiquitin-like domain-containing protein. (89 aa)
LOC101114746Uncharacterized protein. (1175 aa)
LMNB2Lamin B2; Belongs to the intermediate filament family. (539 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (493 aa)
W5P3V9_SHEEPProtein kinase domain-containing protein. (185 aa)
CDK1Cell division cycle 2 protein isoform 1; Belongs to the protein kinase superfamily. (297 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
IST1IST1 factor associated with ESCRT-III. (377 aa)
W5P023_SHEEPUncharacterized protein; Belongs to the AAA ATPase family. (412 aa)
IQCA1LIQ motif containing with AAA domain 1 like. (725 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (538 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (514 aa)
AHCTF1AT-hook containing transcription factor 1. (2297 aa)
NUP133Nucleoporin_C domain-containing protein. (1157 aa)
LEMD3LEM domain containing 3. (856 aa)
RCC1Regulator of chromosome condensation 1. (422 aa)
NUP43Nucleoporin 43. (380 aa)
W5NX37_SHEEPUncharacterized protein. (714 aa)
NUP98Nucleoporin 98. (1816 aa)
ADGRB1Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1493 aa)
W5NVI3_SHEEPTubulin_C domain-containing protein. (172 aa)
VRK2VRK serine/threonine kinase 2. (509 aa)
W5NUI0_SHEEPTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (373 aa)
BANF1Barrier to autointegration factor 1. (89 aa)
ADGRB2Adhesion G protein-coupled receptor B2; Belongs to the G-protein coupled receptor 2 family. (1558 aa)
RPGRUncharacterized protein. (1012 aa)
CHMP6Charged multivesicular body protein 6. (180 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (937 aa)
W5NQ01_SHEEPUncharacterized protein. (396 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (396 aa)
TM9SF1Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (757 aa)
RBM23RNA binding motif protein 23. (463 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
LOC101116286Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
LOC101107266Uncharacterized protein. (222 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (398 aa)
W5QIP1_SHEEPCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (253 aa)
W5QIZ8_SHEEPGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (211 aa)
CC2D1BCoiled-coil and C2 domain containing 1B. (853 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (658 aa)
W5P6X3_SHEEPCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (427 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (391 aa)
CNTD2Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (287 aa)
NDC1NDC1 transmembrane nucleoporin. (676 aa)
VPS4AATPase_AAA_core domain-containing protein. (107 aa)
ENSOARP00000007526annotation not available (107 aa)
CC2D1ACoiled-coil and C2 domain containing 1A. (1143 aa)
NUP160Nucleoporin 160. (1414 aa)
FIGNL1Fidgetin like 1; Belongs to the AAA ATPase family. (682 aa)
NCOA5Nuclear receptor coactivator 5. (579 aa)
KPNB1Karyopherin subunit beta 1. (866 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
NUP188Nucleoporin 188. (1741 aa)
NUP205Nucleoporin 205. (2018 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (484 aa)
EMDEmerin. (206 aa)
MDP1Uncharacterized protein. (165 aa)
IQCA1IQ motif containing with AAA domain 1. (792 aa)
W5QBU8_SHEEPGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (165 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (824 aa)
W5QA93_SHEEPUncharacterized protein. (612 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (586 aa)
RANGAP1Ran GTPase activating protein 1. (622 aa)
BANF2Barrier to autointegration factor 2. (90 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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