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ALDOC ALDOC GOT1L1 GOT1L1 SLC25A12 SLC25A12 GOT2 GOT2 URB2 URB2 G6PC G6PC G6PC2 G6PC2 SLC25A13 SLC25A13 MYCBPAP MYCBPAP ALDOA ALDOA PGAM1 PGAM1 GPI GPI GAPDHS GAPDHS ENO2 ENO2 TPI1 TPI1 ENO3 ENO3 SLC25A11 SLC25A11 G6PC3 G6PC3 ALDOB ALDOB GAPDH GAPDH FBP1 FBP1 FBP2 FBP2 PGK2 PGK2 PC PC ENO1 ENO1 W5PK04_SHEEP W5PK04_SHEEP SLC37A1 SLC37A1 SLC37A2 SLC37A2 SLC37A4 SLC37A4 GOT1 GOT1 SLC37A3 SLC37A3 PM20D2 PM20D2 PGAM2 PGAM2 MDH2 MDH2 W5PYK2_SHEEP W5PYK2_SHEEP FAM126B FAM126B SLC25A1 SLC25A1 W5Q7K8_SHEEP W5Q7K8_SHEEP PCK1 PCK1 ENO4 ENO4 SLC25A10 SLC25A10 IQCH IQCH MDH1B MDH1B W5QBT3_SHEEP W5QBT3_SHEEP PGK1 PGK1 PCK2 PCK2 MDH1 MDH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (459 aa)
GOT1L1Glutamic-oxaloacetic transaminase 1 like 1. (461 aa)
SLC25A12Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (751 aa)
GOT2Aspartate aminotransferase. (430 aa)
URB2URB2 ribosome biogenesis homolog. (1521 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
G6PC2Glucose-6-phosphatase catalytic subunit 2. (359 aa)
SLC25A13Solute carrier family 25 member 13; Belongs to the mitochondrial carrier (TC 2.A.29) family. (675 aa)
MYCBPAPMYCBP associated protein. (964 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
PGAM1Uncharacterized protein. (208 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (557 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase, spermatogenic; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (370 aa)
ENO2Enolase 2. (434 aa)
TPI1Triosephosphate isomerase. (214 aa)
ENO3Enolase 3. (434 aa)
SLC25A11SLC25A11; Belongs to the mitochondrial carrier (TC 2.A.29) family. (314 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (341 aa)
ALDOBFructose-bisphosphate aldolase B. (364 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (334 aa)
FBP1Fructose-1,6-bisphosphatase 1; Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism [...] (338 aa)
FBP2Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. (339 aa)
PGK2Phosphoglycerate kinase. (417 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1149 aa)
ENO1Enolase 1. (452 aa)
W5PK04_SHEEPPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (200 aa)
SLC37A1Solute carrier family 37 member 1. (530 aa)
SLC37A2Solute carrier family 37 member 2. (501 aa)
SLC37A4Solute carrier family 37 member 4. (451 aa)
GOT1Aspartate aminotransferase. (413 aa)
SLC37A3Solute carrier family 37 member 3. (495 aa)
PM20D2Peptidase M20 domain-containing protein 2; Belongs to the peptidase M20A family. (429 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (256 aa)
MDH2Malate dehydrogenase 2. (405 aa)
W5PYK2_SHEEPEnolase_C domain-containing protein. (317 aa)
FAM126BFamily with sequence similarity 126 member B. (586 aa)
SLC25A1Solute carrier family 25 member 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (188 aa)
W5Q7K8_SHEEPGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (286 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (620 aa)
ENO4Enolase 4. (613 aa)
SLC25A10Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (292 aa)
IQCHIQ motif containing H. (1057 aa)
MDH1BMalate dehydrogenase 1B. (521 aa)
W5QBT3_SHEEPGlyceraldehyde-3-phosphate dehydrogenase. (327 aa)
PGK1Phosphoglycerate kinase. (420 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (724 aa)
MDH1Malate dehydrogenase. (352 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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