11 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ALDH16A1	Aldehyde dehydrogenase family 16 member A1. (807 aa)
	W5NRG4_SHEEP	ADH_zinc_N domain-containing protein. (128 aa)
	W5NUH5_SHEEP	Uncharacterized protein. (281 aa)
	W5NVS0_SHEEP	ADH_N domain-containing protein. (126 aa)
	ACSS1	Acetyl-coenzyme A synthetase. (579 aa)
	ALDH2	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (520 aa)
	ACSS2	Acyl-CoA synthetase short chain family member 2. (714 aa)
	ALDH1A1	Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo. (501 aa)
	LOC101111965	PKS_ER domain-containing protein. (378 aa)
	W5Q247_SHEEP	PKS_ER domain-containing protein. (375 aa)
	ADH5	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACSS1	ACSS2	ENSOARP00000007097	ENSOARP00000011568	Acetyl-coenzyme A synthetase.	Acyl-CoA synthetase short chain family member 2.	0.906
ACSS1	ALDH16A1	ENSOARP00000007097	ENSOARP00000014020	Acetyl-coenzyme A synthetase.	Aldehyde dehydrogenase family 16 member A1.	0.480
ACSS1	ALDH1A1	ENSOARP00000007097	ENSOARP00000013613	Acetyl-coenzyme A synthetase.	Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo.	0.510
ACSS1	ALDH2	ENSOARP00000007097	ENSOARP00000011426	Acetyl-coenzyme A synthetase.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.942
ACSS2	ACSS1	ENSOARP00000011568	ENSOARP00000007097	Acyl-CoA synthetase short chain family member 2.	Acetyl-coenzyme A synthetase.	0.906
ACSS2	ALDH16A1	ENSOARP00000011568	ENSOARP00000014020	Acyl-CoA synthetase short chain family member 2.	Aldehyde dehydrogenase family 16 member A1.	0.457
ACSS2	ALDH1A1	ENSOARP00000011568	ENSOARP00000013613	Acyl-CoA synthetase short chain family member 2.	Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo.	0.510
ACSS2	ALDH2	ENSOARP00000011568	ENSOARP00000011426	Acyl-CoA synthetase short chain family member 2.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.940
ADH5	ALDH1A1	ENSOARP00000016892	ENSOARP00000013613	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo.	0.950
ADH5	ALDH2	ENSOARP00000016892	ENSOARP00000011426	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.957
ALDH16A1	ACSS1	ENSOARP00000014020	ENSOARP00000007097	Aldehyde dehydrogenase family 16 member A1.	Acetyl-coenzyme A synthetase.	0.480
ALDH16A1	ACSS2	ENSOARP00000014020	ENSOARP00000011568	Aldehyde dehydrogenase family 16 member A1.	Acyl-CoA synthetase short chain family member 2.	0.457
ALDH1A1	ACSS1	ENSOARP00000013613	ENSOARP00000007097	Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo.	Acetyl-coenzyme A synthetase.	0.510
ALDH1A1	ACSS2	ENSOARP00000013613	ENSOARP00000011568	Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo.	Acyl-CoA synthetase short chain family member 2.	0.510
ALDH1A1	ADH5	ENSOARP00000013613	ENSOARP00000016892	Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo.	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	0.950
ALDH1A1	LOC101111965	ENSOARP00000013613	ENSOARP00000016513	Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo.	PKS_ER domain-containing protein.	0.949
ALDH1A1	W5NRG4_SHEEP	ENSOARP00000013613	ENSOARP00000000754	Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo.	ADH_zinc_N domain-containing protein.	0.949
ALDH1A1	W5NUH5_SHEEP	ENSOARP00000013613	ENSOARP00000001819	Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo.	Uncharacterized protein.	0.932
ALDH1A1	W5NVS0_SHEEP	ENSOARP00000013613	ENSOARP00000002266	Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo.	ADH_N domain-containing protein.	0.513
ALDH2	ACSS1	ENSOARP00000011426	ENSOARP00000007097	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Acetyl-coenzyme A synthetase.	0.942