node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CALM3 | CALML4 | ENSOARP00000011414 | ENSOARP00000019762 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Calmodulin like 4. | 0.963 |
CALM3 | CALML5 | ENSOARP00000011414 | ENSOARP00000004928 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Calmodulin like 5. | 0.963 |
CALM3 | LOC105614854 | ENSOARP00000011414 | ENSOARP00000022802 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Uncharacterized protein; Belongs to the calmodulin family. | 0.949 |
CALM3 | NPPA | ENSOARP00000011414 | ENSOARP00000019562 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity); Belongs to the natriuretic peptide family. | 0.461 |
CALM3 | PDE1A | ENSOARP00000011414 | ENSOARP00000018050 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Phosphodiesterase. | 0.968 |
CALM3 | PDE1B | ENSOARP00000011414 | ENSOARP00000017297 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Phosphodiesterase. | 0.960 |
CALM3 | PDE1C | ENSOARP00000011414 | ENSOARP00000007610 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Phosphodiesterase. | 0.952 |
CALM3 | PDE5A | ENSOARP00000011414 | ENSOARP00000017204 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Phosphodiesterase. | 0.549 |
CALM3 | PRKACA | ENSOARP00000011414 | ENSOARP00000006933 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...] | 0.983 |
CALM3 | PRKACB | ENSOARP00000011414 | ENSOARP00000014812 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.983 |
CALML4 | CALM3 | ENSOARP00000019762 | ENSOARP00000011414 | Calmodulin like 4. | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | 0.963 |
CALML4 | CALML5 | ENSOARP00000019762 | ENSOARP00000004928 | Calmodulin like 4. | Calmodulin like 5. | 0.966 |
CALML4 | LOC105614854 | ENSOARP00000019762 | ENSOARP00000022802 | Calmodulin like 4. | Uncharacterized protein; Belongs to the calmodulin family. | 0.967 |
CALML4 | NPPA | ENSOARP00000019762 | ENSOARP00000019562 | Calmodulin like 4. | Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity); Belongs to the natriuretic peptide family. | 0.450 |
CALML4 | PDE1A | ENSOARP00000019762 | ENSOARP00000018050 | Calmodulin like 4. | Phosphodiesterase. | 0.963 |
CALML4 | PDE1B | ENSOARP00000019762 | ENSOARP00000017297 | Calmodulin like 4. | Phosphodiesterase. | 0.962 |
CALML4 | PDE1C | ENSOARP00000019762 | ENSOARP00000007610 | Calmodulin like 4. | Phosphodiesterase. | 0.961 |
CALML4 | PDE5A | ENSOARP00000019762 | ENSOARP00000017204 | Calmodulin like 4. | Phosphodiesterase. | 0.568 |
CALML4 | PRKACA | ENSOARP00000019762 | ENSOARP00000006933 | Calmodulin like 4. | cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...] | 0.984 |
CALML4 | PRKACB | ENSOARP00000019762 | ENSOARP00000014812 | Calmodulin like 4. | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.984 |