8 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EIF4EBP1	Eukaryotic translation initiation factor 4E binding protein 1. (120 aa)
	LOC101107259	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (425 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
	OXTR	Oxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (368 aa)
	ARG1	Arginase. (352 aa)
	RPS6	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
	ODC1	Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (461 aa)
	ARG2	Arginase. (354 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARG1	ARG2	ENSOARP00000014964	ENSOARP00000022756	Arginase.	Arginase.	0.910
ARG1	LOC101107259	ENSOARP00000014964	ENSOARP00000001565	Arginase.	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.987
ARG1	ODC1	ENSOARP00000014964	ENSOARP00000016555	Arginase.	Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.981
ARG2	ARG1	ENSOARP00000022756	ENSOARP00000014964	Arginase.	Arginase.	0.910
ARG2	LOC101107259	ENSOARP00000022756	ENSOARP00000001565	Arginase.	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.990
ARG2	ODC1	ENSOARP00000022756	ENSOARP00000016555	Arginase.	Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.982
EIF4EBP1	MTOR	ENSOARP00000001164	ENSOARP00000002935	Eukaryotic translation initiation factor 4E binding protein 1.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.998
EIF4EBP1	RPS6	ENSOARP00000001164	ENSOARP00000015292	Eukaryotic translation initiation factor 4E binding protein 1.	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	0.599
LOC101107259	ARG1	ENSOARP00000001565	ENSOARP00000014964	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	Arginase.	0.987
LOC101107259	ARG2	ENSOARP00000001565	ENSOARP00000022756	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	Arginase.	0.990
LOC101107259	ODC1	ENSOARP00000001565	ENSOARP00000016555	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.903
MTOR	EIF4EBP1	ENSOARP00000002935	ENSOARP00000001164	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	Eukaryotic translation initiation factor 4E binding protein 1.	0.998
MTOR	RPS6	ENSOARP00000002935	ENSOARP00000015292	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	0.600
ODC1	ARG1	ENSOARP00000016555	ENSOARP00000014964	Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	Arginase.	0.981
ODC1	ARG2	ENSOARP00000016555	ENSOARP00000022756	Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	Arginase.	0.982
ODC1	LOC101107259	ENSOARP00000016555	ENSOARP00000001565	Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.903
RPS6	EIF4EBP1	ENSOARP00000015292	ENSOARP00000001164	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	Eukaryotic translation initiation factor 4E binding protein 1.	0.599
RPS6	MTOR	ENSOARP00000015292	ENSOARP00000002935	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.600