20 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DCUN1D5	DCN1-like protein. (209 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (334 aa)
	CUL9	Cullin 9; Belongs to the cullin family. (2522 aa)
	DDB2	Damage specific DNA binding protein 2. (427 aa)
	CUL7	Cullin 7; Belongs to the cullin family. (1698 aa)
	W5P1I7_SHEEP	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
	CAND1	Cullin associated and neddylation dissociated 1. (1230 aa)
	ELOB	Elongin B. (118 aa)
	NEDD8	NEDD8 ubiquitin like modifier. (77 aa)
	UBE2F	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (185 aa)
	CUL1	CULLIN_2 domain-containing protein; Belongs to the cullin family. (759 aa)
	RBX1	Ring-box 1. (112 aa)
	CUL2	Cullin 2; Belongs to the cullin family. (748 aa)
	KLHL3	Kelch like family member 3. (589 aa)
	CUL4B	Cullin 4B; Belongs to the cullin family. (959 aa)
	DDB1	Damage specific DNA binding protein 1. (1151 aa)
	CUL5	Cullin 5; Belongs to the cullin family. (780 aa)
	ACADVL	Acyl-CoA dehydrogenase very long chain. (707 aa)
	UBA3	Ubiquitin like modifier activating enzyme 3. (478 aa)
	CUL4A	Cullin 4A; Belongs to the cullin family. (718 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAND1	CUL1	ENSOARP00000002250	ENSOARP00000020109	Cullin associated and neddylation dissociated 1.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.986
CAND1	CUL2	ENSOARP00000002250	ENSOARP00000018280	Cullin associated and neddylation dissociated 1.	Cullin 2; Belongs to the cullin family.	0.863
CAND1	CUL4A	ENSOARP00000002250	ENSOARP00000008670	Cullin associated and neddylation dissociated 1.	Cullin 4A; Belongs to the cullin family.	0.884
CAND1	CUL4B	ENSOARP00000002250	ENSOARP00000014203	Cullin associated and neddylation dissociated 1.	Cullin 4B; Belongs to the cullin family.	0.828
CAND1	CUL5	ENSOARP00000002250	ENSOARP00000011663	Cullin associated and neddylation dissociated 1.	Cullin 5; Belongs to the cullin family.	0.816
CAND1	DCUN1D5	ENSOARP00000002250	ENSOARP00000004880	Cullin associated and neddylation dissociated 1.	DCN1-like protein.	0.762
CAND1	DDB1	ENSOARP00000002250	ENSOARP00000012561	Cullin associated and neddylation dissociated 1.	Damage specific DNA binding protein 1.	0.759
CAND1	DDB2	ENSOARP00000002250	ENSOARP00000005861	Cullin associated and neddylation dissociated 1.	Damage specific DNA binding protein 2.	0.675
CAND1	ELOB	ENSOARP00000002250	ENSOARP00000000332	Cullin associated and neddylation dissociated 1.	Elongin B.	0.786
CAND1	KLHL3	ENSOARP00000002250	ENSOARP00000016491	Cullin associated and neddylation dissociated 1.	Kelch like family member 3.	0.721
CAND1	NEDD8	ENSOARP00000002250	ENSOARP00000020587	Cullin associated and neddylation dissociated 1.	NEDD8 ubiquitin like modifier.	0.931
CAND1	RBX1	ENSOARP00000002250	ENSOARP00000019147	Cullin associated and neddylation dissociated 1.	Ring-box 1.	0.942
CAND1	UBA3	ENSOARP00000002250	ENSOARP00000010829	Cullin associated and neddylation dissociated 1.	Ubiquitin like modifier activating enzyme 3.	0.667
CAND1	UBE2F	ENSOARP00000002250	ENSOARP00000020353	Cullin associated and neddylation dissociated 1.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.738
CAND1	W5P1I7_SHEEP	ENSOARP00000002250	ENSOARP00000004286	Cullin associated and neddylation dissociated 1.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.833
CUL1	CAND1	ENSOARP00000020109	ENSOARP00000002250	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Cullin associated and neddylation dissociated 1.	0.986
CUL1	CUL2	ENSOARP00000020109	ENSOARP00000018280	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Cullin 2; Belongs to the cullin family.	0.722
CUL1	CUL4A	ENSOARP00000020109	ENSOARP00000008670	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Cullin 4A; Belongs to the cullin family.	0.698
CUL1	CUL4B	ENSOARP00000020109	ENSOARP00000014203	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Cullin 4B; Belongs to the cullin family.	0.804
CUL1	CUL5	ENSOARP00000020109	ENSOARP00000011663	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Cullin 5; Belongs to the cullin family.	0.648