STRINGSTRING
CUL2 CUL2 RBX1 RBX1 CUL1 CUL1 NEDD8 NEDD8 CUL3 CUL3 ELOB ELOB CUL7 CUL7 GAPDH GAPDH CUL4A CUL4A CUL5 CUL5 UVRAG UVRAG CUL4B CUL4B SKP1 SKP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CUL2Cullin 2; Belongs to the cullin family. (748 aa)
RBX1Ring-box 1. (112 aa)
CUL1CULLIN_2 domain-containing protein; Belongs to the cullin family. (759 aa)
NEDD8NEDD8 ubiquitin like modifier. (77 aa)
CUL3Cullin 3; Belongs to the cullin family. (746 aa)
ELOBElongin B. (118 aa)
CUL7Cullin 7; Belongs to the cullin family. (1698 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (334 aa)
CUL4ACullin 4A; Belongs to the cullin family. (718 aa)
CUL5Cullin 5; Belongs to the cullin family. (780 aa)
UVRAGC2 domain-containing protein. (661 aa)
CUL4BCullin 4B; Belongs to the cullin family. (959 aa)
SKP1Uncharacterized protein; Belongs to the SKP1 family. (186 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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