Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARG1 | ARG2 | ENSOARP00000014964 | ENSOARP00000022756 | Arginase. | Arginase. | 0.910 |
| ARG1 | CD4 | ENSOARP00000014964 | ENSOARP00000006749 | Arginase. | T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. | 0.899 |
| ARG1 | FOXP3 | ENSOARP00000014964 | ENSOARP00000011020 | Arginase. | Fork-head domain-containing protein. | 0.641 |
| ARG1 | IFNG | ENSOARP00000014964 | ENSOARP00000002060 | Arginase. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | 0.810 |
| ARG1 | IL10 | ENSOARP00000014964 | ENSOARP00000006744 | Arginase. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.907 |
| ARG1 | IL13 | ENSOARP00000014964 | ENSOARP00000016026 | Arginase. | Uncharacterized protein. | 0.906 |
| ARG1 | IL18 | ENSOARP00000014964 | ENSOARP00000017389 | Arginase. | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. | 0.466 |
| ARG1 | IL2 | ENSOARP00000014964 | ENSOARP00000000019 | Arginase. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | 0.484 |
| ARG1 | IL21 | ENSOARP00000014964 | ENSOARP00000019188 | Arginase. | Interleukin; Belongs to the IL-15/IL-21 family. | 0.495 |
| ARG1 | IL4 | ENSOARP00000014964 | ENSOARP00000015980 | Arginase. | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | 0.882 |
| ARG1 | IL5 | ENSOARP00000014964 | ENSOARP00000016128 | Arginase. | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. | 0.476 |
| ARG1 | NOS2 | ENSOARP00000014964 | ENSOARP00000017986 | Arginase. | Nitric oxide synthase; Produces nitric oxide (NO). | 0.981 |
| ARG2 | ARG1 | ENSOARP00000022756 | ENSOARP00000014964 | Arginase. | Arginase. | 0.910 |
| ARG2 | CD4 | ENSOARP00000022756 | ENSOARP00000006749 | Arginase. | T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. | 0.758 |
| ARG2 | H3-4 | ENSOARP00000022756 | ENSOARP00000001546 | Arginase. | Histone H3; Belongs to the histone H3 family. | 0.408 |
| ARG2 | IFNG | ENSOARP00000022756 | ENSOARP00000002060 | Arginase. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | 0.649 |
| ARG2 | IL10 | ENSOARP00000022756 | ENSOARP00000006744 | Arginase. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.860 |
| ARG2 | IL13 | ENSOARP00000022756 | ENSOARP00000016026 | Arginase. | Uncharacterized protein. | 0.625 |
| ARG2 | IL4 | ENSOARP00000022756 | ENSOARP00000015980 | Arginase. | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | 0.661 |
| ARG2 | NOS2 | ENSOARP00000022756 | ENSOARP00000017986 | Arginase. | Nitric oxide synthase; Produces nitric oxide (NO). | 0.959 |
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