25 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SOX30	SRY-box transcription factor 30. (692 aa)
	CATSPER1	Cation channel sperm associated 1. (699 aa)
	SPAG6	Sperm associated antigen 6. (512 aa)
	TBP	Uncharacterized protein. (315 aa)
	OCLN	Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa)
	RFX2	Regulatory factor X2. (720 aa)
	TNP2	Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. (136 aa)
	PRM3	Protamine 3. (93 aa)
	EN2	Homeobox protein engrailed-like. (243 aa)
	DDX4	DEAD-box helicase 4; Belongs to the DEAD box helicase family. (732 aa)
	STRA8	Stimulated by retinoic acid 8. (366 aa)
	TDRD6	Tudor domain containing 6. (2015 aa)
	YBX2	Y-box binding protein 2. (355 aa)
	FHL5	Four and a half LIM domains 5. (286 aa)
	SPEM1	Spermatid maturation 1. (313 aa)
	SYCP3	Synaptonemal complex protein 3. (225 aa)
	PIWIL1	Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family. (935 aa)
	TJP1	Tight junction protein 1; Belongs to the MAGUK family. (1750 aa)
	CREM	cAMP responsive element modulator. (360 aa)
	ODF1	Outer dense fiber of sperm tails 1. (259 aa)
	TDRD5	Tudor domain containing 5. (1039 aa)
	SPO11	SPO11 initiator of meiotic double stranded breaks. (395 aa)
	REC8	REC8 meiotic recombination protein. (592 aa)
	TNP1	Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. (55 aa)
	SOX5	SRY-box transcription factor 5. (728 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CATSPER1	FHL5	ENSOARP00000001567	ENSOARP00000012966	Cation channel sperm associated 1.	Four and a half LIM domains 5.	0.481
CATSPER1	ODF1	ENSOARP00000001567	ENSOARP00000018425	Cation channel sperm associated 1.	Outer dense fiber of sperm tails 1.	0.512
CATSPER1	PRM3	ENSOARP00000001567	ENSOARP00000007019	Cation channel sperm associated 1.	Protamine 3.	0.654
CATSPER1	SOX30	ENSOARP00000001567	ENSOARP00000013472	Cation channel sperm associated 1.	SRY-box transcription factor 30.	0.489
CATSPER1	TNP1	ENSOARP00000001567	ENSOARP00000020868	Cation channel sperm associated 1.	Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.	0.656
CREM	FHL5	ENSOARP00000018100	ENSOARP00000012966	cAMP responsive element modulator.	Four and a half LIM domains 5.	0.741
CREM	ODF1	ENSOARP00000018100	ENSOARP00000018425	cAMP responsive element modulator.	Outer dense fiber of sperm tails 1.	0.416
CREM	PIWIL1	ENSOARP00000018100	ENSOARP00000017472	cAMP responsive element modulator.	Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family.	0.430
CREM	RFX2	ENSOARP00000018100	ENSOARP00000006947	cAMP responsive element modulator.	Regulatory factor X2.	0.405
CREM	SOX30	ENSOARP00000018100	ENSOARP00000013472	cAMP responsive element modulator.	SRY-box transcription factor 30.	0.453
CREM	SPAG6	ENSOARP00000018100	ENSOARP00000001760	cAMP responsive element modulator.	Sperm associated antigen 6.	0.547
CREM	SYCP3	ENSOARP00000018100	ENSOARP00000016365	cAMP responsive element modulator.	Synaptonemal complex protein 3.	0.441
CREM	TNP1	ENSOARP00000018100	ENSOARP00000020868	cAMP responsive element modulator.	Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.	0.579
DDX4	PIWIL1	ENSOARP00000008205	ENSOARP00000017472	DEAD-box helicase 4; Belongs to the DEAD box helicase family.	Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family.	0.681
DDX4	REC8	ENSOARP00000008205	ENSOARP00000020623	DEAD-box helicase 4; Belongs to the DEAD box helicase family.	REC8 meiotic recombination protein.	0.489
DDX4	SOX30	ENSOARP00000008205	ENSOARP00000013472	DEAD-box helicase 4; Belongs to the DEAD box helicase family.	SRY-box transcription factor 30.	0.520
DDX4	SPAG6	ENSOARP00000008205	ENSOARP00000001760	DEAD-box helicase 4; Belongs to the DEAD box helicase family.	Sperm associated antigen 6.	0.403
DDX4	SPO11	ENSOARP00000008205	ENSOARP00000019324	DEAD-box helicase 4; Belongs to the DEAD box helicase family.	SPO11 initiator of meiotic double stranded breaks.	0.584
DDX4	STRA8	ENSOARP00000008205	ENSOARP00000009039	DEAD-box helicase 4; Belongs to the DEAD box helicase family.	Stimulated by retinoic acid 8.	0.839
DDX4	SYCP3	ENSOARP00000008205	ENSOARP00000016365	DEAD-box helicase 4; Belongs to the DEAD box helicase family.	Synaptonemal complex protein 3.	0.899