6 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RNF212B	Ring finger protein 212B. (300 aa)
	FGR	Tyrosine-protein kinase. (522 aa)
	ERCC1	ERCC excision repair 1, endonuclease non-catalytic subunit. (299 aa)
	MSH4	MutS homolog 4. (935 aa)
	RAD50	Zinc-hook domain-containing protein. (1444 aa)
	SPO11	SPO11 initiator of meiotic double stranded breaks. (395 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ERCC1	MSH4	ENSOARP00000010674	ENSOARP00000013633	ERCC excision repair 1, endonuclease non-catalytic subunit.	MutS homolog 4.	0.631
ERCC1	RAD50	ENSOARP00000010674	ENSOARP00000016117	ERCC excision repair 1, endonuclease non-catalytic subunit.	Zinc-hook domain-containing protein.	0.449
MSH4	ERCC1	ENSOARP00000013633	ENSOARP00000010674	MutS homolog 4.	ERCC excision repair 1, endonuclease non-catalytic subunit.	0.631
MSH4	RNF212B	ENSOARP00000013633	ENSOARP00000020786	MutS homolog 4.	Ring finger protein 212B.	0.856
MSH4	SPO11	ENSOARP00000013633	ENSOARP00000019324	MutS homolog 4.	SPO11 initiator of meiotic double stranded breaks.	0.974
RAD50	ERCC1	ENSOARP00000016117	ENSOARP00000010674	Zinc-hook domain-containing protein.	ERCC excision repair 1, endonuclease non-catalytic subunit.	0.449
RAD50	SPO11	ENSOARP00000016117	ENSOARP00000019324	Zinc-hook domain-containing protein.	SPO11 initiator of meiotic double stranded breaks.	0.654
RNF212B	MSH4	ENSOARP00000020786	ENSOARP00000013633	Ring finger protein 212B.	MutS homolog 4.	0.856
RNF212B	SPO11	ENSOARP00000020786	ENSOARP00000019324	Ring finger protein 212B.	SPO11 initiator of meiotic double stranded breaks.	0.695
SPO11	MSH4	ENSOARP00000019324	ENSOARP00000013633	SPO11 initiator of meiotic double stranded breaks.	MutS homolog 4.	0.974
SPO11	RAD50	ENSOARP00000019324	ENSOARP00000016117	SPO11 initiator of meiotic double stranded breaks.	Zinc-hook domain-containing protein.	0.654
SPO11	RNF212B	ENSOARP00000019324	ENSOARP00000020786	SPO11 initiator of meiotic double stranded breaks.	Ring finger protein 212B.	0.695