node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTG1 | ALB | ENSOARP00000019868 | ENSOARP00000014782 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.848 |
ACTG1 | GAPDH | ENSOARP00000019868 | ENSOARP00000008476 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.936 |
ALB | ACTG1 | ENSOARP00000014782 | ENSOARP00000019868 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.848 |
ALB | GAPDH | ENSOARP00000014782 | ENSOARP00000008476 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.889 |
ALB | SYCP3 | ENSOARP00000014782 | ENSOARP00000016365 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Synaptonemal complex protein 3. | 0.458 |
EMSY | RAD51C | ENSOARP00000013783 | ENSOARP00000012408 | EMSY transcriptional repressor, BRCA2 interacting. | RAD51 paralog C. | 0.517 |
GAPDH | ACTG1 | ENSOARP00000008476 | ENSOARP00000019868 | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.936 |
GAPDH | ALB | ENSOARP00000008476 | ENSOARP00000014782 | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.889 |
MEIOB | MLH1 | ENSOARP00000017923 | ENSOARP00000017782 | Uncharacterized protein. | MutL homolog 1. | 0.612 |
MEIOB | RAD51C | ENSOARP00000017923 | ENSOARP00000012408 | Uncharacterized protein. | RAD51 paralog C. | 0.741 |
MEIOB | SPATA22 | ENSOARP00000017923 | ENSOARP00000018037 | Uncharacterized protein. | Spermatogenesis associated 22. | 0.935 |
MEIOB | SPO11 | ENSOARP00000017923 | ENSOARP00000019324 | Uncharacterized protein. | SPO11 initiator of meiotic double stranded breaks. | 0.745 |
MEIOB | SYCE3 | ENSOARP00000017923 | ENSOARP00000021400 | Uncharacterized protein. | Synaptonemal complex central element protein 3. | 0.817 |
MEIOB | SYCP3 | ENSOARP00000017923 | ENSOARP00000016365 | Uncharacterized protein. | Synaptonemal complex protein 3. | 0.729 |
MLH1 | MEIOB | ENSOARP00000017782 | ENSOARP00000017923 | MutL homolog 1. | Uncharacterized protein. | 0.612 |
MLH1 | RAD51C | ENSOARP00000017782 | ENSOARP00000012408 | MutL homolog 1. | RAD51 paralog C. | 0.624 |
MLH1 | SPO11 | ENSOARP00000017782 | ENSOARP00000019324 | MutL homolog 1. | SPO11 initiator of meiotic double stranded breaks. | 0.533 |
MLH1 | SYCE3 | ENSOARP00000017782 | ENSOARP00000021400 | MutL homolog 1. | Synaptonemal complex central element protein 3. | 0.562 |
MLH1 | SYCP3 | ENSOARP00000017782 | ENSOARP00000016365 | MutL homolog 1. | Synaptonemal complex protein 3. | 0.837 |
RAD51C | EMSY | ENSOARP00000012408 | ENSOARP00000013783 | RAD51 paralog C. | EMSY transcriptional repressor, BRCA2 interacting. | 0.517 |