STRINGSTRING
FGF10 FGF10 SLC1A7 SLC1A7 PGR PGR FGFR2 FGFR2 SLC1A6 SLC1A6 FGFR4 FGFR4 SLC2A3 SLC2A3 FGFR1 FGFR1 LOC101107259 LOC101107259 SLC6A9 SLC6A9 ARG2 ARG2 FGF7 FGF7 AZIN2 AZIN2 SLC2A1 SLC2A1 SLC1A2 SLC1A2 TSC2 TSC2 HGF HGF ODC1 ODC1 ARG1 ARG1 SLC1A1 SLC1A1 SLC7A1 SLC7A1 SLC5A1 SLC5A1 SLC1A5 SLC1A5 SLC1A3 SLC1A3 AGMAT AGMAT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
SLC1A7Amino acid transporter. (529 aa)
PGRProgesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation. (347 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
SLC1A6Amino acid transporter. (580 aa)
FGFR4Fibroblast growth factor receptor. (810 aa)
SLC2A3Solute carrier family 2, facilitated glucose transporter member 3; Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport. (494 aa)
FGFR1Fibroblast growth factor receptor. (788 aa)
LOC101107259Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (425 aa)
SLC6A9Uncharacterized protein. (441 aa)
ARG2Arginase. (354 aa)
FGF7Fibroblast growth factor 7; Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation (By similarity); Belongs to the heparin-binding growth factors family. (194 aa)
AZIN2Antizyme inhibitor 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (519 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1; Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. (492 aa)
SLC1A2Amino acid transporter. (574 aa)
TSC2TSC complex subunit 2. (1811 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (734 aa)
ODC1Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (461 aa)
ARG1Arginase. (352 aa)
SLC1A1Amino acid transporter. (524 aa)
SLC7A1AA_permease_C domain-containing protein. (319 aa)
SLC5A1Sodium/glucose cotransporter 1; Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. (664 aa)
SLC1A5Amino acid transporter. (546 aa)
SLC1A3Amino acid transporter. (542 aa)
AGMATAgmatinase; Belongs to the arginase family. (361 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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