STRINGSTRING
ALB ALB CCZ1 CCZ1 RAB4A RAB4A AAMDC AAMDC LAMP1 LAMP1 CDC16 CDC16 RAB5B RAB5B MON1A MON1A VPS33A VPS33A LAMP2 LAMP2 APPL1 APPL1 TBC1D15 TBC1D15 CTSB CTSB EEA1 EEA1 RAB22A RAB22A ACTG1 ACTG1 RAB5C RAB5C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (609 aa)
CCZ1Uncharacterized protein. (482 aa)
RAB4AUncharacterized protein. (233 aa)
AAMDCAdipogenesis associated Mth938 domain containing. (122 aa)
LAMP1Lysosomal associated membrane protein 1. (392 aa)
CDC16Cell division cycle 16. (620 aa)
RAB5BRAB5B, member RAS oncogene family. (227 aa)
MON1AMON1 homolog A, secretory trafficking associated. (653 aa)
VPS33AUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (596 aa)
LAMP2Lysosomal associated membrane protein 2. (452 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (693 aa)
TBC1D15TBC1 domain family member 15. (682 aa)
CTSBCathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). Belongs to the peptidase C1 family. (335 aa)
EEA1Early endosome antigen 1. (1413 aa)
RAB22ARAB22A, member RAS oncogene family. (194 aa)
ACTG1Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (377 aa)
RAB5CUncharacterized protein. (216 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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