12 items (Ovis aries) - STRING interaction network

Nodes:

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second shell of interactors

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Your Input:
	STRA8	Stimulated by retinoic acid 8. (366 aa)
	AMH	AMH_N domain-containing protein. (213 aa)
	SALL4	Spalt like transcription factor 4. (1004 aa)
	INSL3	Insulin-like protein 3. (131 aa)
	SYCP3	Synaptonemal complex protein 3. (225 aa)
	DAZL	Deleted in azoospermia like. (258 aa)
	SPO11	SPO11 initiator of meiotic double stranded breaks. (395 aa)
	CYP19	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (424 aa)
	PRDM1	PR/SET domain 1. (883 aa)
	BMP15	Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity). (402 aa)
	FOXL2	Fork-head domain-containing protein. (158 aa)
	CYP17A1	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...] (509 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMH	BMP15	ENSOARP00000015429	ENSOARP00000010055	AMH_N domain-containing protein.	Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity).	0.929
AMH	CYP17A1	ENSOARP00000015429	ENSOARP00000002254	AMH_N domain-containing protein.	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	0.883
AMH	CYP19	ENSOARP00000015429	ENSOARP00000022542	AMH_N domain-containing protein.	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	0.919
AMH	DAZL	ENSOARP00000015429	ENSOARP00000016597	AMH_N domain-containing protein.	Deleted in azoospermia like.	0.579
AMH	FOXL2	ENSOARP00000015429	ENSOARP00000007704	AMH_N domain-containing protein.	Fork-head domain-containing protein.	0.858
AMH	INSL3	ENSOARP00000015429	ENSOARP00000016055	AMH_N domain-containing protein.	Insulin-like protein 3.	0.712
AMH	STRA8	ENSOARP00000015429	ENSOARP00000009039	AMH_N domain-containing protein.	Stimulated by retinoic acid 8.	0.574
AMH	SYCP3	ENSOARP00000015429	ENSOARP00000016365	AMH_N domain-containing protein.	Synaptonemal complex protein 3.	0.527
BMP15	AMH	ENSOARP00000010055	ENSOARP00000015429	Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity).	AMH_N domain-containing protein.	0.929
BMP15	CYP17A1	ENSOARP00000010055	ENSOARP00000002254	Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity).	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	0.538
BMP15	CYP19	ENSOARP00000010055	ENSOARP00000022542	Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity).	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	0.697
BMP15	DAZL	ENSOARP00000010055	ENSOARP00000016597	Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity).	Deleted in azoospermia like.	0.562
BMP15	FOXL2	ENSOARP00000010055	ENSOARP00000007704	Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity).	Fork-head domain-containing protein.	0.674
BMP15	STRA8	ENSOARP00000010055	ENSOARP00000009039	Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity).	Stimulated by retinoic acid 8.	0.488
CYP17A1	AMH	ENSOARP00000002254	ENSOARP00000015429	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	AMH_N domain-containing protein.	0.883
CYP17A1	BMP15	ENSOARP00000002254	ENSOARP00000010055	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity).	0.538
CYP17A1	CYP19	ENSOARP00000002254	ENSOARP00000022542	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	0.956
CYP17A1	INSL3	ENSOARP00000002254	ENSOARP00000016055	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	Insulin-like protein 3.	0.835
CYP17A1	STRA8	ENSOARP00000002254	ENSOARP00000009039	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	Stimulated by retinoic acid 8.	0.416
CYP19	AMH	ENSOARP00000022542	ENSOARP00000015429	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	AMH_N domain-containing protein.	0.919