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IL1A | Interleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. (309 aa) | ||||
KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (979 aa) | ||||
CLDN11 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa) | ||||
HMGB4 | High mobility group box 4. (194 aa) | ||||
HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5. (1039 aa) | ||||
ESX1 | Homeobox domain-containing protein. (284 aa) | ||||
DEFB123 | Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (67 aa) | ||||
MLLT10 | MLLT10 histone lysine methyltransferase DOT1L cofactor. (954 aa) | ||||
CALCR | Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (508 aa) | ||||
FBXO39 | F-box protein 39. (443 aa) | ||||
NDUFV2 | Uncharacterized protein. (246 aa) | ||||
ITGA6 | Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1069 aa) | ||||
PSMG4 | Proteasome assembly chaperone 4. (102 aa) | ||||
TMEM190 | Transmembrane protein 190. (180 aa) | ||||
BMI1 | RING-type domain-containing protein. (326 aa) | ||||
NASP | Uncharacterized protein. (778 aa) | ||||
FGF1 | Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3. Its binding to integrin, subsequent ternary complex formation with int [...] (155 aa) | ||||
ADAM2 | ADAM metallopeptidase domain 2. (741 aa) | ||||
CYP17A1 | Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...] (509 aa) | ||||
SLC2A3 | Solute carrier family 2, facilitated glucose transporter member 3; Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport. (494 aa) | ||||
RETN | Uncharacterized protein. (109 aa) | ||||
S100A13 | S100 calcium binding protein A13; Belongs to the S-100 family. (98 aa) | ||||
CCDC117 | Coiled-coil domain containing 117. (278 aa) | ||||
GTF2A1 | General transcription factor IIA subunit 1. (376 aa) | ||||
PEBP1 | Uncharacterized protein. (187 aa) | ||||
CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (147 aa) | ||||
SGF29 | SAGA complex associated factor 29. (293 aa) | ||||
TIMP2 | NTR domain-containing protein. (217 aa) | ||||
MDK | Midkine. (143 aa) | ||||
CYP11A1 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones (By similarity). Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into [...] (520 aa) | ||||
RET | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1123 aa) | ||||
STRA6 | Stimulated by retinoic acid 6. (744 aa) | ||||
TSPAN33 | Tetraspanin. (267 aa) | ||||
TOP2B | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1613 aa) | ||||
FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. The activity of isoform FSH-R1 is mediated by G proteins which activate adenylate cyclase. Isoform FSH-R2 and isoform FSH-R3 also bind FSH, but this does not result in activation of adenylate cyclase. Isoform FSH-R3 may be involved in calcium signaling. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways (By similarity). (656 aa) | ||||
TULP4 | TUB like protein 4. (1160 aa) | ||||
RARB | Retinoic acid receptor beta. (448 aa) | ||||
YWHAB | 14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (282 aa) | ||||
HELLS | Helicase, lymphoid specific. (837 aa) | ||||
TMEM147 | Transmembrane protein 147. (247 aa) | ||||
SLPI | Antileukoproteinase; Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. Modulates the inflammatory and immune responses after bacterial infection, and after infection by the intracellular parasite L.major. Down-regulates responses to bacterial lipopolysaccharide (LPS). Plays a role in regulating the activation of NF-kappa-B and inflammatory responses. Has antimicrobial activity against mycobacteria, but not against salmonella. Contributes to normal resistance against infection by M.tuberculosis. Required for normal resistance t [...] (140 aa) | ||||
ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (370 aa) | ||||
SUN5 | Sad1 and UNC84 domain containing 5. (380 aa) | ||||
CARHSP1 | Calcium regulated heat stable protein 1. (159 aa) | ||||
TKTL1 | Transketolase like 1. (622 aa) | ||||
ETV4 | ETS variant 4. (486 aa) | ||||
WDR82 | WD repeat domain 82. (313 aa) | ||||
SPACA9 | Sperm acrosome associated 9. (223 aa) | ||||
FOXO1 | Fork-head domain-containing protein. (445 aa) | ||||
GPATCH4 | G-patch domain containing 4. (406 aa) | ||||
PDGFA | Platelet derived growth factor subunit A. (187 aa) | ||||
HORMAD2 | HORMA domain containing 2. (308 aa) | ||||
SETX | Senataxin. (2662 aa) | ||||
DMRTB1 | DMRT like family B with proline rich C-terminal 1. (368 aa) | ||||
NDUFA4 | Uncharacterized protein. (82 aa) | ||||
CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (962 aa) | ||||
SSR4 | Signal sequence receptor subunit 4. (173 aa) | ||||
PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa) | ||||
TNP2 | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. (136 aa) | ||||
PRM3 | Protamine 3. (93 aa) | ||||
STPG1 | Sperm tail PG-rich repeat containing 1. (335 aa) | ||||
TRMT112 | tRNA methyltransferase subunit 11-2. (125 aa) | ||||
HMGN3 | High mobility group nucleosomal binding domain 3. (95 aa) | ||||
PSMA8 | Proteasome subunit alpha type. (250 aa) | ||||
KLF4 | Uncharacterized protein. (340 aa) | ||||
TEX29 | Testis expressed 29. (162 aa) | ||||
CD74 | CD74 molecule. (294 aa) | ||||
W5PBV5_SHEEP | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (380 aa) | ||||
CHD4 | Uncharacterized protein. (1881 aa) | ||||
DDX4 | DEAD-box helicase 4; Belongs to the DEAD box helicase family. (732 aa) | ||||
LYAR | Ly1 antibody reactive. (382 aa) | ||||
SIVA1 | Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (176 aa) | ||||
HUWE1 | HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4418 aa) | ||||
RBBP8 | Uncharacterized protein. (887 aa) | ||||
NME8 | NME/NM23 family member 8. (588 aa) | ||||
STRA8 | Stimulated by retinoic acid 8. (366 aa) | ||||
TEX101 | UPAR/Ly6 domain-containing protein. (253 aa) | ||||
PTCH1 | Patched 1. (1450 aa) | ||||
SMC1A | Structural maintenance of chromosomes protein. (1233 aa) | ||||
GAS6 | Growth arrest specific 6. (594 aa) | ||||
FATE1 | Miff domain-containing protein. (180 aa) | ||||
NKAPL | NFKB activating protein like. (399 aa) | ||||
KNTC1 | Kinetochore associated 1. (2242 aa) | ||||
W5PIE5_SHEEP | HMG box domain-containing protein. (237 aa) | ||||
ENO1 | Enolase 1. (452 aa) | ||||
PLPPR3 | Phospholipid phosphatase related 3. (716 aa) | ||||
ALDH1A3 | Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (493 aa) | ||||
BCL6B | BCL6B transcription repressor. (473 aa) | ||||
PIWIL4 | Piwi like RNA-mediated gene silencing 4; Belongs to the argonaute family. (854 aa) | ||||
FMR1 | Fragile X mental retardation 1. (632 aa) | ||||
PTN | Pleiotrophin. (168 aa) | ||||
SMC3 | Structural maintenance of chromosomes protein. (1217 aa) | ||||
KLC3 | Kinesin light chain 3. (495 aa) | ||||
SMCHD1 | Structural maintenance of chromosomes flexible hinge domain containing 1. (1872 aa) | ||||
ACVR2A | Activin receptor type-2A; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (547 aa) | ||||
SPACA3 | Sperm acrosome associated 3; Belongs to the glycosyl hydrolase 22 family. (163 aa) | ||||
JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (312 aa) | ||||
IGF1R | Tyrosine-protein kinase receptor. (1122 aa) | ||||
AKAP4 | A-kinase anchoring protein 4. (860 aa) | ||||
LPIN2 | Lipin 2. (889 aa) | ||||
SYCE2 | Synaptonemal complex central element protein 2. (184 aa) | ||||
RAD21 | RAD21 cohesin complex component. (630 aa) | ||||
CCNA1 | Cyclin A1; Belongs to the cyclin family. (454 aa) | ||||
CXCR4 | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (353 aa) | ||||
KDM1B | Lysine demethylase 1B. (821 aa) | ||||
PAX7 | Paired box 7. (501 aa) | ||||
FOXO3 | Fork-head domain-containing protein. (473 aa) | ||||
CLEC3B | C-type lectin domain family 3 member B. (205 aa) | ||||
VIM | Vimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. (467 aa) | ||||
NANOS2 | Nanos C2HC-type zinc finger 2; Belongs to the nanos family. (138 aa) | ||||
WASHC1 | WH2 domain-containing protein. (269 aa) | ||||
CYP26B1 | Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa) | ||||
CCDC38 | Coiled-coil domain containing 38. (564 aa) | ||||
W5PQU9_SHEEP | Uncharacterized protein. (170 aa) | ||||
ZPBP2 | Zona pellucida binding protein 2. (326 aa) | ||||
FZR1 | WD_REPEATS_REGION domain-containing protein. (493 aa) | ||||
ANXA1 | Annexin. (346 aa) | ||||
ALDH1A1 | Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo. (501 aa) | ||||
RBM47 | RNA binding motif protein 47. (548 aa) | ||||
ASB17 | Ankyrin repeat and SOCS box containing 17. (295 aa) | ||||
SPACA1 | Sperm acrosome associated 1. (292 aa) | ||||
UCHL1 | Ubiquitin carboxyl-terminal hydrolase. (252 aa) | ||||
DMRT1 | Doublesex and mab-3 related transcription factor 1. (332 aa) | ||||
SPEM1 | Spermatid maturation 1. (313 aa) | ||||
NR6A1 | Nuclear receptor subfamily 6 group A member 1. (434 aa) | ||||
NR5A1 | Nuclear receptor subfamily 5 group A member 1. (439 aa) | ||||
SOX9 | SRY-box transcription factor 9. (383 aa) | ||||
ALB | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (609 aa) | ||||
RHOA | RHOA. (193 aa) | ||||
STRBP | Uncharacterized protein. (676 aa) | ||||
LGALS1 | Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase (By similarity). Strong inducer of T-cell apoptosis. (108 aa) | ||||
RARA | Retinoic acid receptor alpha. (453 aa) | ||||
CCDC124 | Uncharacterized protein. (149 aa) | ||||
TDRD1 | Uncharacterized protein. (1197 aa) | ||||
FTH1 | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (154 aa) | ||||
AMH | AMH_N domain-containing protein. (213 aa) | ||||
ELAVL2 | ELAV-like protein; Belongs to the RRM elav family. (388 aa) | ||||
AR | Androgen receptor. (881 aa) | ||||
IZUMO4 | IZUMO family member 4. (201 aa) | ||||
INCENP | Inner centromere protein. (866 aa) | ||||
NKG7 | Natural killer cell granule protein 7. (157 aa) | ||||
LOC101113728 | Clusterin alpha chain; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysos [...] (446 aa) | ||||
ZNF518A | Zinc finger protein 518A. (1480 aa) | ||||
UTF1 | Uncharacterized protein. (108 aa) | ||||
INSL3 | Insulin-like protein 3. (131 aa) | ||||
IRF1 | Interferon regulatory factor. (322 aa) | ||||
SHBG | Sex hormone binding globulin. (425 aa) | ||||
GATA4 | GATA binding protein 4. (346 aa) | ||||
SYCP3 | Synaptonemal complex protein 3. (225 aa) | ||||
EIF1AX | X-linked eukaryotic translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (144 aa) | ||||
DAZL | Deleted in azoospermia like. (258 aa) | ||||
DMC1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (342 aa) | ||||
KITLG | Soluble KIT ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or M [...] (274 aa) | ||||
PTPRC | Protein tyrosine phosphatase receptor type C. (1235 aa) | ||||
BTG3 | B cell translocation protein 3. (252 aa) | ||||
NME5 | NME/NM23 family member 5; Belongs to the NDK family. (209 aa) | ||||
CXADR | Uncharacterized protein. (365 aa) | ||||
FGFR3 | Fibroblast growth factor receptor 3. (664 aa) | ||||
TSPAN5 | Tetraspanin. (226 aa) | ||||
ATP5F1E | ATP synthase F1 subunit epsilon. (51 aa) | ||||
GFRA1 | GDNF family receptor alpha 1. (335 aa) | ||||
SUN3 | Sad1 and UNC84 domain containing 3. (359 aa) | ||||
PIWIL1 | Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family. (935 aa) | ||||
WT1 | WT1 transcription factor. (450 aa) | ||||
CCDC112 | Coiled-coil domain containing 112. (512 aa) | ||||
EGR1 | DUF3446 domain-containing protein. (298 aa) | ||||
MLH1 | MutL homolog 1. (758 aa) | ||||
TMEM89 | Transmembrane protein 89. (159 aa) | ||||
MEIOB | Uncharacterized protein. (202 aa) | ||||
W5Q5L3_SHEEP | Uncharacterized protein. (4513 aa) | ||||
SPATA22 | Spermatogenesis associated 22. (326 aa) | ||||
VPS29 | Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (186 aa) | ||||
F2R | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (421 aa) | ||||
ODF1 | Outer dense fiber of sperm tails 1. (259 aa) | ||||
PARD3 | Par-3 family cell polarity regulator. (1328 aa) | ||||
ACVR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (468 aa) | ||||
ECSCR | Uncharacterized protein. (245 aa) | ||||
PROS1 | Protein S. (675 aa) | ||||
PLK1 | Serine/threonine-protein kinase PLK. (605 aa) | ||||
ITGB1 | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (798 aa) | ||||
FTH1-2 | Ferritin heavy chain, N-terminally processed; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). (233 aa) | ||||
CHD1 | Chromodomain helicase DNA binding protein 1. (1716 aa) | ||||
POMC | Corticotropin-like intermediary peptide; [Corticotropin]: Stimulates the adrenal glands to release cortisol. [Melanocyte-stimulating hormone beta]: Increases the pigmentation of skin by increasing melanin production in melanocytes. [Met-enkephalin]: Endogenous opiate. (254 aa) | ||||
AURKA | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (405 aa) | ||||
DNAJB8 | Uncharacterized protein. (96 aa) | ||||
RAD21L1 | RAD21 cohesin complex component like 1. (554 aa) | ||||
CD44 | CD44 molecule (Indian blood group). (705 aa) | ||||
AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (406 aa) | ||||
PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1090 aa) | ||||
KLF2 | Uncharacterized protein. (112 aa) | ||||
DPPA4 | DCR domain-containing protein. (309 aa) | ||||
REC8 | REC8 meiotic recombination protein. (592 aa) | ||||
CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (553 aa) | ||||
TPPP2 | Tubulin polymerization promoting protein family member 2. (171 aa) | ||||
NGF | Nerve growth factor; Belongs to the NGF-beta family. (388 aa) | ||||
ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (802 aa) | ||||
INHA | Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins; Belongs to the TGF-beta family. (360 aa) | ||||
TYRO3 | TYRO3 protein tyrosine kinase. (817 aa) | ||||
HSD3B1 | 3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (375 aa) | ||||
MPL | MPL proto-oncogene, thrombopoietin receptor. (633 aa) | ||||
ETV5 | ETS variant 5. (551 aa) | ||||
SPATA3 | Uncharacterized protein. (229 aa) | ||||
SPATA16 | Spermatogenesis associated 16. (562 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) | ||||
CLEC12B | C-type lectin domain family 12 member B. (274 aa) | ||||
OAZ3 | Ornithine decarboxylase antizyme 3. (234 aa) | ||||
KLRF1 | Killer cell lectin like receptor F1. (235 aa) | ||||
TNFRSF1A | Uncharacterized protein. (277 aa) |