(9 nodes) (2023) Neuronal Cytoglobin in the Auditory Brainstem of Rat and Mouse: Distribution, Cochlear Projection, and Nitric Oxide Production. network (Ovis aries)

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Your Input:
	NOS1	Nitric oxide synthase, brain; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR (By similarity); Belongs to the NOS family. (1463 aa)
	NGB	Neuroglobin; Belongs to the globin family. (151 aa)
	CYGB	GLOBIN domain-containing protein; Belongs to the globin family. (144 aa)
	NOS2	Nitric oxide synthase; Produces nitric oxide (NO). (1154 aa)
	MB	Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (154 aa)
	P4HA2	Prolyl 4-hydroxylase subunit alpha 2. (538 aa)
	ALB	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (609 aa)
	P4HA3	Prolyl 4-hydroxylase subunit alpha 3. (547 aa)
	P4HA1	Prolyl 4-hydroxylase subunit alpha 1. (534 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	MB	ENSOARP00000014782	ENSOARP00000020014	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.	0.945
ALB	NOS2	ENSOARP00000014782	ENSOARP00000017986	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Nitric oxide synthase; Produces nitric oxide (NO).	0.551
CYGB	MB	ENSOARP00000007399	ENSOARP00000020014	GLOBIN domain-containing protein; Belongs to the globin family.	Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.	0.523
CYGB	NGB	ENSOARP00000007399	ENSOARP00000002495	GLOBIN domain-containing protein; Belongs to the globin family.	Neuroglobin; Belongs to the globin family.	0.906
MB	ALB	ENSOARP00000020014	ENSOARP00000014782	Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.945
MB	CYGB	ENSOARP00000020014	ENSOARP00000007399	Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.	GLOBIN domain-containing protein; Belongs to the globin family.	0.523
MB	NGB	ENSOARP00000020014	ENSOARP00000002495	Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.	Neuroglobin; Belongs to the globin family.	0.920
NGB	CYGB	ENSOARP00000002495	ENSOARP00000007399	Neuroglobin; Belongs to the globin family.	GLOBIN domain-containing protein; Belongs to the globin family.	0.906
NGB	MB	ENSOARP00000002495	ENSOARP00000020014	Neuroglobin; Belongs to the globin family.	Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.	0.920
NOS1	NOS2	ENSOARP00000004517	ENSOARP00000017986	Nitric oxide synthase, brain; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR (By similarity); Belongs to the NOS family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.910
NOS2	ALB	ENSOARP00000017986	ENSOARP00000014782	Nitric oxide synthase; Produces nitric oxide (NO).	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.551
NOS2	NOS1	ENSOARP00000017986	ENSOARP00000004517	Nitric oxide synthase; Produces nitric oxide (NO).	Nitric oxide synthase, brain; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR (By similarity); Belongs to the NOS family.	0.910
P4HA1	P4HA2	ENSOARP00000007878	ENSOARP00000016515	Prolyl 4-hydroxylase subunit alpha 1.	Prolyl 4-hydroxylase subunit alpha 2.	0.940
P4HA1	P4HA3	ENSOARP00000007878	ENSOARP00000010387	Prolyl 4-hydroxylase subunit alpha 1.	Prolyl 4-hydroxylase subunit alpha 3.	0.910
P4HA2	P4HA1	ENSOARP00000016515	ENSOARP00000007878	Prolyl 4-hydroxylase subunit alpha 2.	Prolyl 4-hydroxylase subunit alpha 1.	0.940
P4HA2	P4HA3	ENSOARP00000016515	ENSOARP00000010387	Prolyl 4-hydroxylase subunit alpha 2.	Prolyl 4-hydroxylase subunit alpha 3.	0.924
P4HA3	P4HA1	ENSOARP00000010387	ENSOARP00000007878	Prolyl 4-hydroxylase subunit alpha 3.	Prolyl 4-hydroxylase subunit alpha 1.	0.910
P4HA3	P4HA2	ENSOARP00000010387	ENSOARP00000016515	Prolyl 4-hydroxylase subunit alpha 3.	Prolyl 4-hydroxylase subunit alpha 2.	0.924