5 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NOS2	Nitric oxide synthase; Produces nitric oxide (NO). (1154 aa)
	CALML4	Calmodulin like 4. (197 aa)
	LOC105614854	Uncharacterized protein; Belongs to the calmodulin family. (145 aa)
	CALML5	Calmodulin like 5. (149 aa)
	CALM3	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). (149 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALM3	CALML4	ENSOARP00000011414	ENSOARP00000019762	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Calmodulin like 4.	0.963
CALM3	CALML5	ENSOARP00000011414	ENSOARP00000004928	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Calmodulin like 5.	0.963
CALM3	LOC105614854	ENSOARP00000011414	ENSOARP00000022802	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Uncharacterized protein; Belongs to the calmodulin family.	0.949
CALM3	NOS2	ENSOARP00000011414	ENSOARP00000017986	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Nitric oxide synthase; Produces nitric oxide (NO).	0.976
CALML4	CALM3	ENSOARP00000019762	ENSOARP00000011414	Calmodulin like 4.	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	0.963
CALML4	CALML5	ENSOARP00000019762	ENSOARP00000004928	Calmodulin like 4.	Calmodulin like 5.	0.966
CALML4	LOC105614854	ENSOARP00000019762	ENSOARP00000022802	Calmodulin like 4.	Uncharacterized protein; Belongs to the calmodulin family.	0.967
CALML4	NOS2	ENSOARP00000019762	ENSOARP00000017986	Calmodulin like 4.	Nitric oxide synthase; Produces nitric oxide (NO).	0.965
CALML5	CALM3	ENSOARP00000004928	ENSOARP00000011414	Calmodulin like 5.	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	0.963
CALML5	CALML4	ENSOARP00000004928	ENSOARP00000019762	Calmodulin like 5.	Calmodulin like 4.	0.966
CALML5	LOC105614854	ENSOARP00000004928	ENSOARP00000022802	Calmodulin like 5.	Uncharacterized protein; Belongs to the calmodulin family.	0.967
CALML5	NOS2	ENSOARP00000004928	ENSOARP00000017986	Calmodulin like 5.	Nitric oxide synthase; Produces nitric oxide (NO).	0.976
LOC105614854	CALM3	ENSOARP00000022802	ENSOARP00000011414	Uncharacterized protein; Belongs to the calmodulin family.	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	0.949
LOC105614854	CALML4	ENSOARP00000022802	ENSOARP00000019762	Uncharacterized protein; Belongs to the calmodulin family.	Calmodulin like 4.	0.967
LOC105614854	CALML5	ENSOARP00000022802	ENSOARP00000004928	Uncharacterized protein; Belongs to the calmodulin family.	Calmodulin like 5.	0.967
LOC105614854	NOS2	ENSOARP00000022802	ENSOARP00000017986	Uncharacterized protein; Belongs to the calmodulin family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.955
NOS2	CALM3	ENSOARP00000017986	ENSOARP00000011414	Nitric oxide synthase; Produces nitric oxide (NO).	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	0.976
NOS2	CALML4	ENSOARP00000017986	ENSOARP00000019762	Nitric oxide synthase; Produces nitric oxide (NO).	Calmodulin like 4.	0.965
NOS2	CALML5	ENSOARP00000017986	ENSOARP00000004928	Nitric oxide synthase; Produces nitric oxide (NO).	Calmodulin like 5.	0.976
NOS2	LOC105614854	ENSOARP00000017986	ENSOARP00000022802	Nitric oxide synthase; Produces nitric oxide (NO).	Uncharacterized protein; Belongs to the calmodulin family.	0.955