STRINGSTRING
WDFY1 WDFY1 RUFY1 RUFY1 RUFY2 RUFY2 ZFYVE9 ZFYVE9 MTMR3 MTMR3 FGD1 FGD1 FGD3 FGD3 WDFY2 WDFY2 FYCO1 FYCO1 MTMR4 MTMR4 ZFYVE27 ZFYVE27 FGD2 FGD2 ZFYVE16 ZFYVE16 PLEKHF2 PLEKHF2 EEA1 EEA1 FGD6 FGD6 RBSN RBSN FGD5 FGD5 HGS HGS ANKFY1 ANKFY1 PIKFYVE PIKFYVE FGD4 FGD4 ZFYVE26 ZFYVE26 ZFYVE1 ZFYVE1 WDFY3 WDFY3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WDFY1Uncharacterized protein. (423 aa)
RUFY1Uncharacterized protein. (608 aa)
RUFY2RUN and FYVE domain containing 2. (614 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1424 aa)
MTMR3Myotubularin related protein 3. (1197 aa)
FGD1FYVE, RhoGEF and PH domain containing 1. (960 aa)
FGD3FYVE, RhoGEF and PH domain containing 3. (767 aa)
WDFY2WD repeat and FYVE domain containing 2. (433 aa)
FYCO1FYVE and coiled-coil domain containing 1. (1225 aa)
MTMR4Myotubularin related protein 4. (1196 aa)
ZFYVE27Zinc finger FYVE-type containing 27. (408 aa)
FGD2FYVE, RhoGEF and PH domain containing 2. (659 aa)
ZFYVE16Zinc finger FYVE-type containing 16. (1544 aa)
PLEKHF2Pleckstrin homology and FYVE domain containing 2. (249 aa)
EEA1Early endosome antigen 1. (1413 aa)
FGD6FYVE, RhoGEF and PH domain containing 6. (1446 aa)
RBSNRabenosyn, RAB effector. (758 aa)
FGD5FYVE, RhoGEF and PH domain containing 5. (1421 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (787 aa)
ANKFY1Ankyrin repeat and FYVE domain containing 1. (1174 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2109 aa)
FGD4FYVE, RhoGEF and PH domain containing 4. (884 aa)
ZFYVE26Zinc finger FYVE-type containing 26. (2521 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (783 aa)
WDFY3WD repeat and FYVE domain containing 3. (3522 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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