48 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GGT6	Gamma-glutamyltransferase 6. (490 aa)
	W5NSD7_SHEEP	Uncharacterized protein. (241 aa)
	RRM1	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (791 aa)
	LOC101107259	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (425 aa)
	LAP3	Leucine aminopeptidase 3. (522 aa)
	SRM	Spermidine synthase; Belongs to the spermidine/spermine synthase family. (221 aa)
	PGD	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (542 aa)
	GCLC	Glutamate-cysteine ligase catalytic subunit. (588 aa)
	LOC101116273	Uncharacterized protein. (241 aa)
	GSTO2	Glutathione S-transferase omega 2; Belongs to the GST superfamily. (243 aa)
	GPX3	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (151 aa)
	GPX8	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
	LOC101112287	PABS domain-containing protein. (365 aa)
	GSR	Uncharacterized protein. (420 aa)
	GSS	Glutathione synthetase. (474 aa)
	MGST3	Microsomal glutathione S-transferase 3. (152 aa)
	PRDX6	Peroxiredoxin 6. (227 aa)
	ANPEP	Aminopeptidase. (968 aa)
	IDH2	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (434 aa)
	GSTP1	Uncharacterized protein; Belongs to the GST superfamily. (209 aa)
	MGST2	Microsomal glutathione S-transferase 2. (146 aa)
	W5PUH4_SHEEP	Uncharacterized protein; Belongs to the GST superfamily. (214 aa)
	GSTT4	Glutathione S-transferase theta 4; Belongs to the GST superfamily. (168 aa)
	W5PVN0_SHEEP	Uncharacterized protein; Belongs to the GST superfamily. (211 aa)
	LOC101118990	Uncharacterized protein; Belongs to the GST superfamily. (239 aa)
	GGT5	Gamma-glutamyltransferase 5. (539 aa)
	GSTA1-1	Uncharacterized protein. (223 aa)
	LOC101106720	Uncharacterized protein; Belongs to the GST superfamily. (223 aa)
	LOC101106976	Uncharacterized protein. (227 aa)
	GSTA4	Glutathione S-transferase alpha 4. (238 aa)
	RRM2	Ribonucleotide reductase regulatory subunit M2. (353 aa)
	ODC1	Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (461 aa)
	NAT8	N-acetyltransferase domain-containing protein. (227 aa)
	GCLM	Glutamate-cysteine ligase modifier subunit. (272 aa)
	GSTA1	Uncharacterized protein. (222 aa)
	GPX5	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (219 aa)
	GSTK1	Glutathione S-transferase kappa. (226 aa)
	GPX6	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (142 aa)
	HPGDS	Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (201 aa)
	RRM2B	Ribonucleotide reductase regulatory TP53 inducible subunit M2B. (434 aa)
	IDH1	Isocitrate dehydrogenase [NADP] cytoplasmic. (414 aa)
	LOC101107401	Uncharacterized protein. (221 aa)
	W5QDB7_SHEEP	Uncharacterized protein. (229 aa)
	LOC101108092	Uncharacterized protein; Belongs to the GST superfamily. (229 aa)
	GSTM3	Glutathione S-transferase. (230 aa)
	CHAC1	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (145 aa)
	MGST1	Microsomal glutathione S-transferase 1. (155 aa)
	GPX2	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (146 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANPEP	CHAC1	ENSOARP00000012699	ENSOARP00000021813	Aminopeptidase.	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	0.900
ANPEP	GCLC	ENSOARP00000012699	ENSOARP00000007582	Aminopeptidase.	Glutamate-cysteine ligase catalytic subunit.	0.958
ANPEP	GCLM	ENSOARP00000012699	ENSOARP00000018264	Aminopeptidase.	Glutamate-cysteine ligase modifier subunit.	0.916
ANPEP	GGT5	ENSOARP00000012699	ENSOARP00000014726	Aminopeptidase.	Gamma-glutamyltransferase 5.	0.919
ANPEP	GGT6	ENSOARP00000012699	ENSOARP00000000102	Aminopeptidase.	Gamma-glutamyltransferase 6.	0.932
ANPEP	GSS	ENSOARP00000012699	ENSOARP00000011646	Aminopeptidase.	Glutathione synthetase.	0.918
ANPEP	LAP3	ENSOARP00000012699	ENSOARP00000003650	Aminopeptidase.	Leucine aminopeptidase 3.	0.953
ANPEP	NAT8	ENSOARP00000012699	ENSOARP00000017714	Aminopeptidase.	N-acetyltransferase domain-containing protein.	0.900
CHAC1	ANPEP	ENSOARP00000021813	ENSOARP00000012699	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Aminopeptidase.	0.900
CHAC1	GGT5	ENSOARP00000021813	ENSOARP00000014726	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Gamma-glutamyltransferase 5.	0.908
CHAC1	GGT6	ENSOARP00000021813	ENSOARP00000000102	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Gamma-glutamyltransferase 6.	0.912
CHAC1	GPX2	ENSOARP00000021813	ENSOARP00000022740	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.901
CHAC1	GPX3	ENSOARP00000021813	ENSOARP00000008509	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.901
CHAC1	GPX5	ENSOARP00000021813	ENSOARP00000018884	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.901
CHAC1	GPX6	ENSOARP00000021813	ENSOARP00000018953	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.901
CHAC1	GPX8	ENSOARP00000021813	ENSOARP00000008548	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.905
CHAC1	GSR	ENSOARP00000021813	ENSOARP00000011212	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Uncharacterized protein.	0.900
CHAC1	GSS	ENSOARP00000021813	ENSOARP00000011646	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Glutathione synthetase.	0.909
CHAC1	GSTA1	ENSOARP00000021813	ENSOARP00000018866	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Uncharacterized protein.	0.660
CHAC1	GSTA1-1	ENSOARP00000021813	ENSOARP00000015830	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Uncharacterized protein.	0.660