STRINGSTRING
MDH2 MDH2 GLDC GLDC MDH1 MDH1 AMT AMT ACO1 ACO1 MCEE MCEE PGP PGP ACO2 ACO2 SHMT1 SHMT1 CAT CAT GLUL GLUL HAO2 HAO2 HAO1 HAO1 HYI HYI AGXT-2 AGXT-2 PCCA PCCA ACAT2 ACAT2 AFMID AFMID GLYCTK GLYCTK ACSS1 ACSS1 DLD DLD SHMT2 SHMT2 PCCB PCCB CS CS ACSS2 ACSS2 HOGA1 HOGA1 ACAT1 ACAT1 GRHPR GRHPR MMUT MMUT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MDH2Malate dehydrogenase 2. (405 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1025 aa)
MDH1Malate dehydrogenase. (352 aa)
AMTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (374 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (903 aa)
MCEEMethylmalonyl-CoA epimerase. (179 aa)
PGPPhosphoglycolate phosphatase. (237 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (783 aa)
SHMT1Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. (486 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (528 aa)
GLULGlutamine synthetase. (373 aa)
HAO2Hydroxyacid oxidase 2. (357 aa)
HAO1Hydroxyacid oxidase 1. (377 aa)
HYIHydroxypyruvate isomerase (putative). (227 aa)
AGXT-2Aminotran_5 domain-containing protein. (108 aa)
PCCAPropionyl-CoA carboxylase subunit alpha. (646 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (432 aa)
AFMIDKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (307 aa)
GLYCTKGlycerate kinase. (523 aa)
ACSS1Acetyl-coenzyme A synthetase. (579 aa)
DLDDihydrolipoyl dehydrogenase. (509 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (343 aa)
PCCBPropionyl-CoA carboxylase subunit beta. (550 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (466 aa)
ACSS2Acyl-CoA synthetase short chain family member 2. (714 aa)
HOGA14-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family. (327 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
GRHPRGlyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa)
MMUTMethylmalonyl-CoA mutase. (755 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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