STRINGSTRING
BDH2 BDH2 ACSM4 ACSM4 ACSM3 ACSM3 HADHA HADHA W5QFN4_SHEEP W5QFN4_SHEEP OXCT2 OXCT2 BDH1 BDH1 HMGCS2 HMGCS2 EHHADH EHHADH L2HGDH L2HGDH ECHS1 ECHS1 GAD1 GAD1 ACAT2 ACAT2 GAD2 GAD2 ABAT ABAT W5P775_SHEEP W5P775_SHEEP HMGCLL1 HMGCLL1 ALDH5A1 ALDH5A1 HMGCL HMGCL HADH HADH HMGCS1 HMGCS1 OXCT1 OXCT1 ACAT1 ACAT1 ACSM5 ACSM5 LOC101120131 LOC101120131 ACSM1 ACSM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BDH23-hydroxybutyrate dehydrogenase 2. (245 aa)
ACSM4Acyl-CoA synthetase medium chain family member 4. (580 aa)
ACSM3Acyl-CoA synthetase medium chain family member 3. (586 aa)
HADHAEnoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
W5QFN4_SHEEPSuccinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (518 aa)
OXCT2Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (518 aa)
BDH13-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (344 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase. (723 aa)
L2HGDHL-2-hydroxyglutarate dehydrogenase. (417 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa)
GAD1Glutamate decarboxylase 1. (599 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (432 aa)
GAD2Glutamate decarboxylase 2. (578 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
W5P775_SHEEPUncharacterized protein. (543 aa)
HMGCLL13-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (266 aa)
ALDH5A1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (447 aa)
HMGCL3-hydroxy-3-methylglutaryl-CoA lyase. (325 aa)
HADHHydroxyacyl-CoA dehydrogenase. (314 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (566 aa)
OXCT1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (520 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
ACSM5Acyl-CoA synthetase medium chain family member 5. (597 aa)
LOC101120131Uncharacterized protein. (577 aa)
ACSM1Acyl-CoA synthetase medium chain family member 1. (587 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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