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| | HERC3 | HECT domain-containing protein. (1050 aa) |
| | SOCS3 | Suppressor of cytokine signaling 3. (229 aa) |
| | ELOB | Elongin B. (118 aa) |
| | FBXO2 | F-box protein 2. (299 aa) |
| | UBE2S | Ubiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (222 aa) |
| | FANCL | FA complementation group L. (374 aa) |
| | LOC101102964 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (286 aa) |
| | UBE2D3 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (171 aa) |
| | UBE2Q1 | Ubiquitin conjugating enzyme E2 Q1. (399 aa) |
| | PIAS2 | Protein inhibitor of activated STAT 2. (621 aa) |
| | WWP2 | E3 ubiquitin-protein ligase. (870 aa) |
| | FBXW11 | F-box and WD repeat domain containing 11. (531 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (709 aa) |
| | PML | Promyelocytic leukemia. (847 aa) |
| | RHOBTB1 | Rho related BTB domain containing 1. (698 aa) |
| | UBOX5 | U-box domain containing 5. (540 aa) |
| | UBA2 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (595 aa) |
| | UBE2E1 | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa) |
| | UBE2E2 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (126 aa) |
| | PRKN | Ubiquitin-like domain-containing protein. (371 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1857 aa) |
| | HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4. (1057 aa) |
| | VHL | Uncharacterized protein. (100 aa) |
| | CUL7 | Cullin 7; Belongs to the cullin family. (1698 aa) |
| | FBXW8 | F-box and WD repeat domain containing 8. (507 aa) |
| | NEDD4L | NEDD4 like E3 ubiquitin protein ligase. (1028 aa) |
| | DDB2 | Damage specific DNA binding protein 2. (427 aa) |
| | UBE2J2 | Ubiquitin conjugating enzyme E2 J2. (260 aa) |
| | UBE2W | UBIQUITIN_CONJUGAT_2 domain-containing protein. (159 aa) |
| | ELOC | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (249 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (607 aa) |
| | UBE4B | Ubiquitination factor E4B. (1363 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (623 aa) |
| | UBE2C | Ubiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (181 aa) |
| | RNF7 | Ring finger protein 7. (113 aa) |
| | ERCC8 | ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (397 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (817 aa) |
| | UBA6 | Ubiquitin like modifier activating enzyme 6. (1057 aa) |
| | UBE3C | Ubiquitin protein ligase E3C. (1086 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1409 aa) |
| | HUWE1 | HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4418 aa) |
| | CUL4A | Cullin 4A; Belongs to the cullin family. (718 aa) |
| | ANAPC13 | Anaphase promoting complex subunit 13. (74 aa) |
| | CDC34 | Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family. (176 aa) |
| | FBXO4 | F-box protein 4. (326 aa) |
| | CDC16 | Cell division cycle 16. (620 aa) |
| | UBE3A | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (875 aa) |
| | CBLC | Cbl proto-oncogene C. (489 aa) |
| | UBE2R2 | Ubiquitin conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. (238 aa) |
| | UBE4A | Ubiquitination factor E4A. (1066 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | UBE2L6 | Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) |
| | UBA3 | Ubiquitin like modifier activating enzyme 3. (478 aa) |
| | BIRC6 | Baculoviral IAP repeat containing 6. (4861 aa) |
| | MID1 | Midline 1. (712 aa) |
| | CUL5 | Cullin 5; Belongs to the cullin family. (780 aa) |
| | SKP2 | F-box domain-containing protein. (476 aa) |
| | SAE1 | SUMO1 activating enzyme subunit 1. (346 aa) |
| | DET1 | Uncharacterized protein. (551 aa) |
| | UBA52 | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa) |
| | CDC27 | Cell division cycle 27. (826 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1151 aa) |
| | AIRE | Autoimmune regulator. (440 aa) |
| | TRIM37 | Tripartite motif containing 37. (961 aa) |
| | UBA7 | Ubiquitin like modifier activating enzyme 7. (998 aa) |
| | UBE2G2 | Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (165 aa) |
| | FZR1 | WD_REPEATS_REGION domain-containing protein. (493 aa) |
| | W5PSS2_SHEEP | E3 ubiquitin-protein ligase. (923 aa) |
| | UBE2J1 | Ubiquitin conjugating enzyme E2 J1. (324 aa) |
| | CUL4B | Cullin 4B; Belongs to the cullin family. (959 aa) |
| | STUB1 | STIP1 homology and U-box containing protein 1. (288 aa) |
| | UBE2D4 | Ubiquitin conjugating enzyme E2 D4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | UBA1 | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1059 aa) |
| | LOC101103187 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa) |
| | UBE2B | Ubiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | COP1 | COP1 E3 ubiquitin ligase. (650 aa) |
| | ANAPC1 | Anaphase promoting complex subunit 1. (1943 aa) |
| | ANAPC5 | Anaphase promoting complex subunit 5. (757 aa) |
| | UBE2I | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (216 aa) |
| | CBL | Cbl proto-oncogene. (851 aa) |
| | UBE2QL1 | Uncharacterized protein. (71 aa) |
| | SMURF2 | E3 ubiquitin-protein ligase. (732 aa) |
| | RCHY1 | RCHY1. (261 aa) |
| | PRPF19 | Pre-mRNA processing factor 19. (504 aa) |
| | UBE3B | Ubiquitin protein ligase E3B. (1073 aa) |
| | HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4838 aa) |
| | CDC23 | Cell division cycle 23. (597 aa) |
| | UBE2L3 | Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | KEAP1 | Kelch like ECH associated protein 1. (615 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (508 aa) |
| | ANAPC7 | Anaphase promoting complex subunit 7. (600 aa) |
| | KLHL13 | Kelch like family member 13. (655 aa) |
| | UBE2E3 | Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. (236 aa) |
| | SIAH1 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa) |
| | CUL2 | Cullin 2; Belongs to the cullin family. (748 aa) |
| | UBR5 | Ubiquitin protein ligase E3 component n-recognin 5. (2818 aa) |
| | RBX1 | Ring-box 1. (112 aa) |
| | ANAPC11 | RING-type domain-containing protein. (84 aa) |
| | UBC | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] (538 aa) |
| | PIAS1 | Protein inhibitor of activated STAT 1. (654 aa) |
| | CUL1 | CULLIN_2 domain-containing protein; Belongs to the cullin family. (759 aa) |
| | CBLB | Cbl proto-oncogene B. (983 aa) |
| | UBE2F | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (185 aa) |
| | UBE2G1 | Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (155 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (542 aa) |
| | UBE2N | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | NHLRC1 | NHL repeat containing E3 ubiquitin protein ligase 1. (240 aa) |
| | ANAPC2-2 | Uncharacterized protein. (185 aa) |
| | CUL3 | Cullin 3; Belongs to the cullin family. (746 aa) |
| | PIAS3 | Protein inhibitor of activated STAT 3. (627 aa) |
| | TRIP12 | Thyroid hormone receptor interactor 12. (2026 aa) |
| | HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (4857 aa) |
| | NEDD4 | E3 ubiquitin-protein ligase. (850 aa) |
