STRINGSTRING
AEA67523.1 AEA67523.1 AEA67532.1 AEA67532.1 AEA67733.1 AEA67733.1 tusA tusA nfuA nfuA thiI thiI AEA70336.1 AEA70336.1 AEA70788.1 AEA70788.1 AEA70806.1 AEA70806.1 miaB miaB erpA erpA AEA71583.1 AEA71583.1 AEA67023.1 AEA67023.1 AEA67090.1 AEA67090.1 trmJ trmJ AEA67093.1 AEA67093.1 iscS iscS AEA67095.1 AEA67095.1 AEA67096.1 AEA67096.1 hscB hscB hscA hscA AEA67099.1 AEA67099.1 AEA67100.1 AEA67100.1 rlmN rlmN AEA67103.1 AEA67103.1 AEA67104.1 AEA67104.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AEA67523.1Conserved hypothetical protein. (313 aa)
AEA67532.1Conserved hypothetical protein; Belongs to the sulfur carrier protein TusA family. (79 aa)
AEA67733.1Morphogene protein; Belongs to the BolA/IbaG family. (99 aa)
tusASulfurtransferase; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. (83 aa)
nfuAFe/S biogenesis protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (194 aa)
thiIPutative thiamine biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (484 aa)
AEA70336.1Cysteine desulfurase. (388 aa)
AEA70788.1Conserved hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (364 aa)
AEA70806.1Glutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily. (113 aa)
miaB(Dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (442 aa)
erpAPutative iron-sulfur cluster insertion protein; Required for insertion of 4Fe-4S clusters for at least IspG. (116 aa)
AEA71583.1Putative heat shock protein. (233 aa)
AEA67023.1Conserved hypothetical protein; Belongs to the BolA/IbaG family. (79 aa)
AEA67090.1Inositol-phosphate phosphatase, (inositol monophosphatase). (272 aa)
trmJPutative tRNA/rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (256 aa)
AEA67093.1Putative Transcription factor, Rrf2 family. (150 aa)
iscSCysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (404 aa)
AEA67095.1NifU family protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (128 aa)
AEA67096.1Putative iron-binding protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. (107 aa)
hscBPutative chaperone protein HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. (173 aa)
hscAPutative chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (620 aa)
AEA67099.1Adrenodoxin family ferredoxin(2Fe-2S iron-sulfur cluster binding domain). (113 aa)
AEA67100.1Conserved hypothetical protein. (66 aa)
rlmNConserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (382 aa)
AEA67103.1Putative fimbrial biogenesis protein. (252 aa)
AEA67104.1Putative Transcription factor, Xre family. (341 aa)
Your Current Organism:
Pseudomonas brassicacearum
NCBI taxonomy Id: 994484
Other names: P. brassicacearum subsp. brassicacearum NFM421, Pseudomonas brassicacearum subsp. brassicacearum CFBP 11874, Pseudomonas brassicacearum subsp. brassicacearum NFM421, Pseudomonas brassicacearum subsp. brassicacearum str. NFM421, Pseudomonas brassicacearum subsp. brassicacearum strain NFM421
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