STRINGSTRING
nfuA nfuA AEA67271.1 AEA67271.1 rimO rimO dinG dinG edd edd AEA67892.1 AEA67892.1 AEA67894.1 AEA67894.1 AEA67927.1 AEA67927.1 AEA67944.1 AEA67944.1 AEA68048.1 AEA68048.1 AEA68166.1 AEA68166.1 pqqE pqqE napA napA AEA68820.1 AEA68820.1 AEA68867.1 AEA68867.1 AEA68868.1 AEA68868.1 AEA68931.1 AEA68931.1 AEA68932.1 AEA68932.1 AEA66430.1 AEA66430.1 AEA69269.1 AEA69269.1 AEA69449.1 AEA69449.1 moaA moaA AEA69456.1 AEA69456.1 AEA69464.1 AEA69464.1 AEA69465.1 AEA69465.1 AEA69489.1 AEA69489.1 AEA69508.1 AEA69508.1 AEA69624.1 AEA69624.1 AEA69681.1 AEA69681.1 AEA66479.1 AEA66479.1 AEA69836.1 AEA69836.1 nuoB nuoB AEA69925.1 AEA69925.1 AEA69926.1 AEA69926.1 nuoI nuoI AEA70090.1 AEA70090.1 leuC leuC AEA70351.1 AEA70351.1 cysH cysH AEA70420.1 AEA70420.1 AEA70441.1 AEA70441.1 AEA70504.1 AEA70504.1 AEA70546.1 AEA70546.1 rlmD rlmD ttcA ttcA AEA66575.1 AEA66575.1 AEA70791.1 AEA70791.1 nth nth AEA70830.1 AEA70830.1 nadA nadA queE queE AEA70898.1 AEA70898.1 AEA71201.1 AEA71201.1 ispH ispH miaB miaB lipA lipA thiC thiC pqqE-2 pqqE-2 bioB bioB AEA71730.1 AEA71730.1 AEA71830.1 AEA71830.1 queG queG AEA66703.1 AEA66703.1 AEA66764.1 AEA66764.1 PSEBR_a84 PSEBR_a84 rlmN rlmN ispG ispG PSEBR_a99 PSEBR_a99 AEA71851.1 AEA71851.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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nfuAFe/S biogenesis protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (194 aa)
AEA67271.1Ferredoxin I; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (107 aa)
rimOConserved hypothetical protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (446 aa)
dinGPutative ATP-dependent helicase, ATP-dependent DNA helicase DinG domain protein; DNA-dependent ATPase and 5'-3' DNA helicase. (714 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (608 aa)
AEA67892.1Putative nitrate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (905 aa)
AEA67894.1Putative nitrite reductase (NAD(P)H), large subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (817 aa)
AEA67927.1Coproporphyrinogen dehydrogenase (oxygen-independent coproporphyrinogen III oxidase); Belongs to the anaerobic coproporphyrinogen-III oxidase family. (460 aa)
AEA67944.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (913 aa)
AEA68048.1Conserved hypothetical protein. (96 aa)
AEA68166.1Putative sulfite reductase (ferredoxin). (552 aa)
pqqECoenzyme PQQ synthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (389 aa)
napANitrate reductase; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (834 aa)
AEA68820.1Putative oxidoreductase, FAD-binding subunit. (726 aa)
AEA68867.1Formate dehydrogenase beta subunit. (519 aa)
AEA68868.1Formate dehydrogenase, alpha subunit. (958 aa)
AEA68931.1Putative Coproporphyrinogen dehydrogenase (oxygen-independent coproporphyrinogen III oxidase). (457 aa)
AEA68932.1Coproporphyrinogen dehydrogenase (oxygen-independent coproporphyrinogen III oxidase); Belongs to the anaerobic coproporphyrinogen-III oxidase family. (462 aa)
AEA66430.1Putative molybdopterin-binding oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (782 aa)
AEA69269.1Putative nitrite reductase, large subunit (nirB); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (853 aa)
AEA69449.1Putative radical-activating enzyme. (228 aa)
moaAPutative molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (330 aa)
AEA69456.1Nitrate reductase, respiratory nitrate reductase 1 alpha chain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1257 aa)
AEA69464.1Conserved hypothetical protein. (296 aa)
AEA69465.1Putative protease. (331 aa)
AEA69489.1Heme d1 biosynthesis protein. (392 aa)
AEA69508.1Conserved hypothetical protein. (78 aa)
AEA69624.1Aconitate hydratase; Belongs to the aconitase/IPM isomerase family. (869 aa)
AEA69681.1Putative hydrogen cyanide synthase HcnA. (108 aa)
AEA66479.1A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (355 aa)
AEA69836.1Conserved hypothetical protein. (102 aa)
nuoBNADH-quinone oxidoreductase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (224 aa)
AEA69925.1NADH-quinone oxidoreductase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (451 aa)
AEA69926.1NADH-quinone oxidoreductase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (904 aa)
nuoINADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (182 aa)
AEA70090.1Glycolate oxidase (iron-sulfur), subunit F. (406 aa)
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (472 aa)
AEA70351.1Aconitate hydratase. (863 aa)
cysHPutative Adenylyl-sulfate reductase (glutathione); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (247 aa)
AEA70420.1Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. (554 aa)
AEA70441.1Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (322 aa)
AEA70504.1Conserved hypothetical protein. (494 aa)
AEA70546.1Succinate dehydrogenase (Succinate dehydrogenase iron-sulfur subunit). (234 aa)
rlmD23S rRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (456 aa)
ttcAtRNA 2-thiocytidine biosynthesis protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (274 aa)
AEA66575.1Glutamate synthase, small subunit. (472 aa)
AEA70791.1Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (341 aa)
nthDNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (212 aa)
AEA70830.1L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (352 aa)
queEPutative radical SAM-superfamily protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (215 aa)
AEA70898.1Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa)
AEA71201.1Conserved hypothetical protein. (259 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (315 aa)
miaB(Dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (442 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (340 aa)
thiCThiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (629 aa)
pqqE-2Coenzyme PQQ synthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (389 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (351 aa)
AEA71730.1Putative L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
AEA71830.1Putative coproporphyrinogen dehydrogenase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (399 aa)
queGConserved hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (359 aa)
AEA66703.1Conserved hypothetical protein. (766 aa)
AEA66764.1Putative precorrin-3B synthase. (449 aa)
PSEBR_a84Conserved hypothetical protein. (387 aa)
rlmNConserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (382 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin); Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (369 aa)
PSEBR_a99Conserved hypothetical protein. (352 aa)
AEA71851.1Putative ferredoxin. (83 aa)
Your Current Organism:
Pseudomonas brassicacearum
NCBI taxonomy Id: 994484
Other names: P. brassicacearum subsp. brassicacearum NFM421, Pseudomonas brassicacearum subsp. brassicacearum CFBP 11874, Pseudomonas brassicacearum subsp. brassicacearum NFM421, Pseudomonas brassicacearum subsp. brassicacearum str. NFM421, Pseudomonas brassicacearum subsp. brassicacearum strain NFM421
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