(27 nodes) Positive regulation of filopodium assembly network (Ochotona princeps)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCR7	C-C motif chemokine receptor 7. (377 aa)
	MYO3A	Myosin IIIA. (1537 aa)
	ENSOPRP00000002303	annotation not available (279 aa)
	PLPPR5	Phospholipid phosphatase related 5. (230 aa)
	NLGN1	Neuroligin 1. (823 aa)
	WASL	WASP like actin nucleation promoting factor. (484 aa)
	CDC42	Cell division cycle 42. (191 aa)
	FNBP1L	Formin binding protein 1 like. (601 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (713 aa)
	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1451 aa)
	CCL21	C-C motif chemokine ligand 21. (134 aa)
	GPM6A	Glycoprotein M6A. (268 aa)
	RHOQ	Ras homolog family member Q. (157 aa)
	NEURL1	Neuralized E3 ubiquitin protein ligase 1. (574 aa)
	AGRN	Agrin. (1960 aa)
	TGFB3	Transforming growth factor beta 3. (294 aa)
	ENSOPRP00000011104	annotation not available (884 aa)
	MYO3B	Myosin IIIB. (1323 aa)
	ENSOPRP00000011658	annotation not available (560 aa)
	NRP1	Neuropilin 1. (922 aa)
	DPYSL3	Dihydropyrimidinase like 3. (681 aa)
	MIEN1	Migration and invasion enhancer 1. (169 aa)
	RIPOR2	RHO family interacting cell polarization regulator 2. (894 aa)
	DNM3	Dynamin 3. (815 aa)
	ENSOPRP00000013831	annotation not available (110 aa)
	TGFBR1	Transforming growth factor beta receptor 1. (470 aa)
	ENSOPRP00000014885	annotation not available (2074 aa)

Your Current Organism:

Ochotona princeps

NCBI taxonomy Id: 9978
Other names: American pika, O. princeps, southern American pika

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARAP1	CDC42	ENSOPRP00000008232	ENSOPRP00000004887	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	Cell division cycle 42.	0.623
ARAP1	ENSOPRP00000013831	ENSOPRP00000008232	ENSOPRP00000013831	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	annotation not available	0.459
ARAP1	RHOQ	ENSOPRP00000008232	ENSOPRP00000009351	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	Ras homolog family member Q.	0.533
CCL21	CCR7	ENSOPRP00000008311	ENSOPRP00000000898	C-C motif chemokine ligand 21.	C-C motif chemokine receptor 7.	0.954
CCR7	CCL21	ENSOPRP00000000898	ENSOPRP00000008311	C-C motif chemokine receptor 7.	C-C motif chemokine ligand 21.	0.954
CDC42	ARAP1	ENSOPRP00000004887	ENSOPRP00000008232	Cell division cycle 42.	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	0.623
CDC42	ENSOPRP00000013831	ENSOPRP00000004887	ENSOPRP00000013831	Cell division cycle 42.	annotation not available	0.648
CDC42	ENSOPRP00000014885	ENSOPRP00000004887	ENSOPRP00000014885	Cell division cycle 42.	annotation not available	0.939
CDC42	FNBP1L	ENSOPRP00000004887	ENSOPRP00000006433	Cell division cycle 42.	Formin binding protein 1 like.	0.892
CDC42	MYO3A	ENSOPRP00000004887	ENSOPRP00000001435	Cell division cycle 42.	Myosin IIIA.	0.704
CDC42	MYO3B	ENSOPRP00000004887	ENSOPRP00000011338	Cell division cycle 42.	Myosin IIIB.	0.709
CDC42	NRP1	ENSOPRP00000004887	ENSOPRP00000011711	Cell division cycle 42.	Neuropilin 1.	0.439
CDC42	PIK3R1	ENSOPRP00000004887	ENSOPRP00000007747	Cell division cycle 42.	Phosphoinositide-3-kinase regulatory subunit 1.	0.945
CDC42	RHOQ	ENSOPRP00000004887	ENSOPRP00000009351	Cell division cycle 42.	Ras homolog family member Q.	0.667
CDC42	TGFBR1	ENSOPRP00000004887	ENSOPRP00000014807	Cell division cycle 42.	Transforming growth factor beta receptor 1.	0.456
CDC42	WASL	ENSOPRP00000004887	ENSOPRP00000003291	Cell division cycle 42.	WASP like actin nucleation promoting factor.	0.994
DNM3	WASL	ENSOPRP00000013552	ENSOPRP00000003291	Dynamin 3.	WASP like actin nucleation promoting factor.	0.699
DPYSL3	NRP1	ENSOPRP00000012037	ENSOPRP00000011711	Dihydropyrimidinase like 3.	Neuropilin 1.	0.542
ENSOPRP00000013831	ARAP1	ENSOPRP00000013831	ENSOPRP00000008232	annotation not available	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	0.459
ENSOPRP00000013831	CDC42	ENSOPRP00000013831	ENSOPRP00000004887	annotation not available	Cell division cycle 42.	0.648