STRINGSTRING
PCYT1A PCYT1A GBA GBA CDS2 CDS2 SPTLC3 SPTLC3 LIPC LIPC CERK CERK GPAT2 GPAT2 GPAT4 GPAT4 LPAR6 LPAR6 LPIN1 LPIN1 AGPAT1 AGPAT1 MOGAT1 MOGAT1 LCLAT1 LCLAT1 GPAM GPAM PNLIPRP1 PNLIPRP1 SMPD2 SMPD2 CHDH CHDH AGPAT5 AGPAT5 LPIN2 LPIN2 ORMDL3 ORMDL3 SGMS2 SGMS2 GPD1 GPD1 GBA2 GBA2 SGMS1 SGMS1 SMPD3 SMPD3 G1T1S8_RABIT G1T1S8_RABIT LPIN3 LPIN3 LPAR2 LPAR2 ACER2 ACER2 LIPF LIPF ORMDL1 ORMDL1 DGKE DGKE CERS5 CERS5 ORMDL2 ORMDL2 PLD1 PLD1 KDSR KDSR MOGAT2 MOGAT2 SMPD1 SMPD1 CEPT1 CEPT1 G1TAW2_RABIT G1TAW2_RABIT PHOSPHO1 PHOSPHO1 MBOAT2 MBOAT2 CDS1 CDS1 ASAH2 ASAH2 SPTSSB SPTSSB G1THC3_RABIT G1THC3_RABIT G1TIK0_RABIT G1TIK0_RABIT CRLS1 CRLS1 G1TLI1_RABIT G1TLI1_RABIT LPAR5 LPAR5 ACER1 ACER1 G1TPL2_RABIT G1TPL2_RABIT PEMT PEMT SPTSSA SPTSSA DGKA DGKA ACER3 ACER3 PISD PISD DEGS1 DEGS1 PLPP2 PLPP2 DGKI DGKI LPAR3 LPAR3 CERS2 CERS2 G1U3X1_RABIT G1U3X1_RABIT CLPS CLPS CERKL CERKL ERICH2 ERICH2 ISM1 ISM1 CERS3 CERS3 PLD3 PLD3 ENSOCUP00000028794 ENSOCUP00000028794 SELENOI SELENOI SMPD4 SMPD4 PCYT1B PCYT1B PLPP4 PLPP4 SPHK1 SPHK1 SPTLC1 SPTLC1 B4GALT6 B4GALT6 ENSOCUP00000032450 ENSOCUP00000032450 ENSOCUP00000032685 ENSOCUP00000032685 PGS1 PGS1 SGPP2 SGPP2 ENSOCUP00000033775 ENSOCUP00000033775 ETNK1 ETNK1 CERS6 CERS6 ETNPPL ETNPPL DEGS2 DEGS2 ENPP2 ENPP2 MGLL MGLL UGCG UGCG ENSOCUP00000036377 ENSOCUP00000036377 PLPP1 PLPP1 ENSOCUP00000037325 ENSOCUP00000037325 LOC100340546 LOC100340546 SPTLC2 SPTLC2 LOC103345697 LOC103345697 SGPP1 SGPP1 LOC100340033 LOC100340033 DGKB DGKB PLPP3 PLPP3 CHKB CHKB MBOAT1 MBOAT1 CERS4 CERS4 SEC14L5 SEC14L5 ASAH1 ASAH1 UGT8 UGT8 DGKH DGKH GPAT3 GPAT3 PNLIPRP2 PNLIPRP2 LPAR1 LPAR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PCYT1APhosphate cytidylyltransferase 1, choline, alpha. (381 aa)
GBAGlucosylceramidase. (536 aa)
CDS2Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (445 aa)
SPTLC3Serine palmitoyltransferase long chain base subunit 3. (551 aa)
LIPCHepatic triacylglycerol lipase; Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin (By similarity). (544 aa)
CERKCeramide kinase. (525 aa)
GPAT2Glycerol-3-phosphate acyltransferase 2, mitochondrial. (754 aa)
GPAT4Glycerol-3-phosphate acyltransferase 4. (456 aa)
LPAR6Lysophosphatidic acid receptor 6; Belongs to the G-protein coupled receptor 1 family. (353 aa)
LPIN1Lipin 1. (1106 aa)
AGPAT11-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (287 aa)
MOGAT1Monoacylglycerol O-acyltransferase 1. (369 aa)
LCLAT1Lysocardiolipin acyltransferase 1. (404 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (844 aa)
PNLIPRP1Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (473 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (423 aa)
CHDHCholine dehydrogenase. (595 aa)
AGPAT5Acyltransf_C domain-containing protein. (197 aa)
LPIN2Lipin 2. (935 aa)
ORMDL3ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
SGMS2Sphingomyelin synthase 2. (365 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic. (117 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (911 aa)
SGMS1Sphingomyelin synthase 1. (419 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (657 aa)
G1T1S8_RABITFA_desaturase domain-containing protein. (316 aa)
LPIN3Lipin 3. (871 aa)
LPAR2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (319 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (292 aa)
LIPFLipase; Belongs to the AB hydrolase superfamily. Lipase family. (401 aa)
ORMDL1Uncharacterized protein. (308 aa)
DGKEDiacylglycerol kinase. (567 aa)
CERS5Ceramide synthase 5. (326 aa)
ORMDL2ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
PLD1Phospholipase. (1031 aa)
KDSR3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (332 aa)
MOGAT2Monoacylglycerol O-acyltransferase 2. (334 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
CEPT1Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (416 aa)
G1TAW2_RABITUncharacterized protein. (310 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (267 aa)
MBOAT2Membrane bound O-acyltransferase domain containing 2; Belongs to the membrane-bound acyltransferase family. (500 aa)
CDS1Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (480 aa)
ASAH2Neutral ceramidase. (759 aa)
SPTSSBSerine palmitoyltransferase small subunit B. (76 aa)
G1THC3_RABITPNPLA domain-containing protein. (443 aa)
G1TIK0_RABITUncharacterized protein. (422 aa)
CRLS1Cardiolipin synthase 1. (213 aa)
G1TLI1_RABITLipid_DES domain-containing protein. (440 aa)
LPAR5Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (369 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (253 aa)
G1TPL2_RABITUncharacterized protein. (276 aa)
PEMTPhosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. (199 aa)
SPTSSAUncharacterized protein. (89 aa)
DGKADiacylglycerol kinase. (734 aa)
ACER3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa)
PISDPhosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. (525 aa)
DEGS1FA_desaturase domain-containing protein. (287 aa)
PLPP2Phospholipid phosphatase 2. (269 aa)
DGKIDiacylglycerol kinase. (914 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (401 aa)
CERS2Ceramide synthase 2. (380 aa)
G1U3X1_RABITUncharacterized protein. (404 aa)
CLPSColipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. (109 aa)
CERKLCeramide kinase like. (542 aa)
ERICH2Uncharacterized protein. (251 aa)
ISM1Isthmin 1. (484 aa)
CERS3Ceramide synthase 3. (411 aa)
PLD3Phospholipase D family member 3. (610 aa)
ENSOCUP00000028794Uncharacterized protein. (124 aa)
SELENOIUncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (474 aa)
SMPD4Sphingomyelin phosphodiesterase 4. (1036 aa)
PCYT1BPhosphate cytidylyltransferase 1, choline, beta. (436 aa)
PLPP4acidPPc domain-containing protein. (457 aa)
SPHK1Sphingosine kinase 1. (455 aa)
SPTLC1Serine palmitoyltransferase long chain base subunit 1. (564 aa)
B4GALT6Beta-1,4-galactosyltransferase 6. (382 aa)
ENSOCUP00000032450Uncharacterized protein. (253 aa)
ENSOCUP00000032685Uncharacterized protein. (308 aa)
PGS1CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. (685 aa)
SGPP2Sphingosine-1-phosphate phosphatase 2. (428 aa)
ENSOCUP00000033775EF-hand domain-containing protein. (521 aa)
ETNK1Ethanolamine kinase 1. (626 aa)
CERS6Ceramide synthase 6. (392 aa)
ETNPPLEthanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (526 aa)
DEGS2Lipid_DES domain-containing protein. (565 aa)
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (939 aa)
MGLLUncharacterized protein. (190 aa)
UGCGUDP-glucose ceramide glucosyltransferase. (406 aa)
ENSOCUP00000036377Uncharacterized protein. (368 aa)
PLPP1Phospholipid phosphatase 1. (286 aa)
ENSOCUP00000037325Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (156 aa)
LOC100340546Uncharacterized protein. (448 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (590 aa)
LOC103345697Uncharacterized protein. (361 aa)
SGPP1acidPPc domain-containing protein. (558 aa)
LOC100340033Uncharacterized protein. (372 aa)
DGKBDiacylglycerol kinase. (803 aa)
PLPP3acidPPc domain-containing protein. (331 aa)
CHKBCholine kinase beta. (342 aa)
MBOAT1Membrane bound O-acyltransferase domain containing 1; Belongs to the membrane-bound acyltransferase family. (511 aa)
CERS4Ceramide synthase 4. (441 aa)
SEC14L5SEC14 like lipid binding 5. (893 aa)
ASAH1N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (412 aa)
UGT8UDP glycosyltransferase 8; Belongs to the UDP-glycosyltransferase family. (574 aa)
DGKHDiacylglycerol kinase. (1257 aa)
GPAT3Glycerol-3-phosphate acyltransferase 3. (607 aa)
PNLIPRP2Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (547 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (391 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.