18 items (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCN2	Cellular communication network factor 2. (437 aa)
	FGF11	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	DCN	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (360 aa)
	ENG	Endoglin. (758 aa)
	FMOD	Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity); Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. (453 aa)
	LTBP1	Latent transforming growth factor beta binding protein 1. (1705 aa)
	TGFB3	Transforming growth factor beta 3. (458 aa)
	LTBP2	Latent transforming growth factor beta binding protein 2. (1809 aa)
	TGFBR3	Transforming growth factor beta receptor 3. (851 aa)
	G1TC56_RABIT	TGFb_propeptide domain-containing protein. (168 aa)
	TGFBR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
	LOC103345451	TGFb_propeptide domain-containing protein. (203 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (486 aa)
	ENSOCUP00000037329	TGFb_propeptide domain-containing protein. (263 aa)
	FGF14	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
	ENSOCUP00000044284	TGFb_propeptide domain-containing protein. (260 aa)
	ENSOCUP00000045925	TGFb_propeptide domain-containing protein. (272 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCN2	DCN	ENSOCUP00000002454	ENSOCUP00000006027	Cellular communication network factor 2.	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.808
CCN2	ENSOCUP00000037329	ENSOCUP00000002454	ENSOCUP00000037329	Cellular communication network factor 2.	TGFb_propeptide domain-containing protein.	0.858
CCN2	ENSOCUP00000044284	ENSOCUP00000002454	ENSOCUP00000044284	Cellular communication network factor 2.	TGFb_propeptide domain-containing protein.	0.858
CCN2	FGF11	ENSOCUP00000002454	ENSOCUP00000003643	Cellular communication network factor 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.559
CCN2	FGF14	ENSOCUP00000002454	ENSOCUP00000040423	Cellular communication network factor 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.554
CCN2	FMOD	ENSOCUP00000002454	ENSOCUP00000007954	Cellular communication network factor 2.	Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity); Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.	0.400
CCN2	G1TC56_RABIT	ENSOCUP00000002454	ENSOCUP00000014344	Cellular communication network factor 2.	TGFb_propeptide domain-containing protein.	0.841
CCN2	LOC103345451	ENSOCUP00000002454	ENSOCUP00000031740	Cellular communication network factor 2.	TGFb_propeptide domain-containing protein.	0.858
CCN2	LTBP1	ENSOCUP00000002454	ENSOCUP00000008280	Cellular communication network factor 2.	Latent transforming growth factor beta binding protein 1.	0.629
CCN2	TGFB2	ENSOCUP00000002454	ENSOCUP00000004578	Cellular communication network factor 2.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.615
CCN2	TGFB3	ENSOCUP00000002454	ENSOCUP00000009817	Cellular communication network factor 2.	Transforming growth factor beta 3.	0.567
CCN2	TGFBR1	ENSOCUP00000002454	ENSOCUP00000035624	Cellular communication network factor 2.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.488
CCN2	TGFBR2	ENSOCUP00000002454	ENSOCUP00000030537	Cellular communication network factor 2.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.561
DCN	CCN2	ENSOCUP00000006027	ENSOCUP00000002454	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Cellular communication network factor 2.	0.808
DCN	ENG	ENSOCUP00000006027	ENSOCUP00000006169	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Endoglin.	0.418
DCN	ENSOCUP00000037329	ENSOCUP00000006027	ENSOCUP00000037329	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	TGFb_propeptide domain-containing protein.	0.984
DCN	ENSOCUP00000044284	ENSOCUP00000006027	ENSOCUP00000044284	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	TGFb_propeptide domain-containing protein.	0.984
DCN	ENSOCUP00000045925	ENSOCUP00000006027	ENSOCUP00000045925	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	TGFb_propeptide domain-containing protein.	0.429
DCN	FGF11	ENSOCUP00000006027	ENSOCUP00000003643	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.861
DCN	FGF14	ENSOCUP00000006027	ENSOCUP00000040423	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.857