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| IL13 | Interleukin 13. (138 aa) | ||||
| IL4R | Fibronectin type-III domain-containing protein. (862 aa) | ||||
| IL10RB | Interleukin 10 receptor subunit beta. (384 aa) | ||||
| IL22 | Interleukin 22. (187 aa) | ||||
| CSF2 | Uncharacterized protein. (144 aa) | ||||
| IL5 | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa) | ||||
| IL22RA1 | Interleukin 22 receptor subunit alpha 1. (679 aa) | ||||
| IL12RB2 | Interleukin 12 receptor subunit beta 2. (883 aa) | ||||
| IL13RA1 | Interleukin 13 receptor subunit alpha 1. (519 aa) | ||||
| IL13RA2 | Interleukin 13 receptor subunit alpha 2. (361 aa) | ||||
| IL5RA | IL6Ra-bind domain-containing protein. (332 aa) | ||||
| IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa) | ||||
| CSF2RB | Colony stimulating factor 2 receptor beta common subunit. (868 aa) | ||||
| IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (304 aa) | ||||
| IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (144 aa) | ||||
| IL10RA | Interleukin 10 receptor subunit alpha. (540 aa) | ||||
| CSF2RA | Fibronectin type-III domain-containing protein. (443 aa) | ||||
| IL6R | Interleukin 6 receptor. (569 aa) | ||||
| IL3RA | Uncharacterized protein. (394 aa) | ||||