(44 nodes) Mixed, incl. Volume-sensitive anion channel activity, and Teneurin Intracellular Region network (Oryctolagus cuniculus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LRR1	Leucine rich repeat protein 1. (419 aa)
	LRRC55	Leucine rich repeat containing 55. (316 aa)
	LINGO4	Leucine rich repeat and Ig domain containing 4. (629 aa)
	FLRT3	Fibronectin leucine rich transmembrane protein 3. (649 aa)
	LRRC8A	Leucine rich repeat containing 8 VRAC subunit A. (769 aa)
	LRRC7	PDZ domain-containing protein. (822 aa)
	PODN	Podocan. (630 aa)
	G1SJA2_RABIT	Anoctamin. (745 aa)
	TENM4	Teneurin transmembrane protein 4. (2706 aa)
	TENM1	Teneurin transmembrane protein 1. (2732 aa)
	TTYH2	Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (505 aa)
	ECM2	Extracellular matrix protein 2. (691 aa)
	TRAIP	TRAF interacting protein. (582 aa)
	LRRC8B	Leucine rich repeat containing 8 VRAC subunit B. (859 aa)
	LRRC8C	Leucine rich repeat containing 8 VRAC subunit C. (803 aa)
	LRRC57	Uncharacterized protein. (239 aa)
	G1T1S4_RABIT	LRRC37 domain-containing protein. (526 aa)
	LHFPL1	LHFPL tetraspan subfamily member 1. (201 aa)
	LRCH2	Leucine rich repeats and calponin homology domain containing 2. (748 aa)
	LRRC10	Uncharacterized protein. (257 aa)
	LRRC2	Leucine rich repeat containing 2. (371 aa)
	KCP	Kielin cysteine rich BMP regulator. (1203 aa)
	NRROS	Negative regulator of reactive oxygen species. (692 aa)
	LRRN1	Leucine rich repeat neuronal 1. (775 aa)
	ADGRL1	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. (1550 aa)
	BEST3	Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (667 aa)
	LRRC8E	Leucine rich repeat containing 8 VRAC subunit E. (827 aa)
	LRRC8D	Leucine rich repeat containing 8 VRAC subunit D. (811 aa)
	KRT78	Keratin 78; Belongs to the intermediate filament family. (514 aa)
	LRRC69	Uncharacterized protein. (347 aa)
	U3KN95_RABIT	Uncharacterized protein. (205 aa)
	LRRC28	Leucine rich repeat containing 28. (428 aa)
	LRRIQ4	Leucine rich repeats and IQ motif containing 4. (600 aa)
	TTYH3	Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (780 aa)
	CLCN3	H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory (By similarity); Belongs to the chloride channel (TC 2.A.49) family. ClC- 3/CLCN3 subfamily. (866 aa)
	ENSOCUP00000029384	SUZ domain-containing protein. (133 aa)
	ADGRL3	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family. (1450 aa)
	TMEM44	Transmembrane protein 44. (517 aa)
	TENM3	Teneurin transmembrane protein 3. (2574 aa)
	ENSOCUP00000040456	Teneurin N-terminal domain-containing protein. (206 aa)
	ENSOCUP00000040703	Uncharacterized protein. (57 aa)
	LRRN2	Leucine rich repeat neuronal 2. (739 aa)
	LRRC1	Leucine rich repeat containing 1. (458 aa)
	ADGRL2	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family. (1494 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRL1	ECM2	ENSOCUP00000023951	ENSOCUP00000007169	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Extracellular matrix protein 2.	0.743
ADGRL1	ENSOCUP00000029384	ENSOCUP00000023951	ENSOCUP00000029384	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	SUZ domain-containing protein.	0.992
ADGRL1	ENSOCUP00000040456	ENSOCUP00000023951	ENSOCUP00000040456	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Teneurin N-terminal domain-containing protein.	0.992
ADGRL1	FLRT3	ENSOCUP00000023951	ENSOCUP00000001372	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Fibronectin leucine rich transmembrane protein 3.	0.880
ADGRL1	G1T1S4_RABIT	ENSOCUP00000023951	ENSOCUP00000010049	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	LRRC37 domain-containing protein.	0.743
ADGRL1	LINGO4	ENSOCUP00000023951	ENSOCUP00000001193	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat and Ig domain containing 4.	0.743
ADGRL1	LRCH2	ENSOCUP00000023951	ENSOCUP00000013995	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeats and calponin homology domain containing 2.	0.708
ADGRL1	LRR1	ENSOCUP00000023951	ENSOCUP00000000106	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat protein 1.	0.743
ADGRL1	LRRC1	ENSOCUP00000023951	ENSOCUP00000042569	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat containing 1.	0.905
ADGRL1	LRRC10	ENSOCUP00000023951	ENSOCUP00000014788	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein.	0.743
ADGRL1	LRRC2	ENSOCUP00000023951	ENSOCUP00000014807	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat containing 2.	0.743
ADGRL1	LRRC55	ENSOCUP00000023951	ENSOCUP00000000393	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat containing 55.	0.743
ADGRL1	LRRC57	ENSOCUP00000023951	ENSOCUP00000009460	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein.	0.743
ADGRL1	LRRC69	ENSOCUP00000023951	ENSOCUP00000026091	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein.	0.743
ADGRL1	LRRC7	ENSOCUP00000023951	ENSOCUP00000001714	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	PDZ domain-containing protein.	0.758
ADGRL1	LRRC8A	ENSOCUP00000023951	ENSOCUP00000001484	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat containing 8 VRAC subunit A.	0.743
ADGRL1	LRRC8B	ENSOCUP00000023951	ENSOCUP00000009276	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat containing 8 VRAC subunit B.	0.744
ADGRL1	LRRC8C	ENSOCUP00000023951	ENSOCUP00000009277	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat containing 8 VRAC subunit C.	0.743
ADGRL1	LRRC8D	ENSOCUP00000023951	ENSOCUP00000025921	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat containing 8 VRAC subunit D.	0.743
ADGRL1	LRRC8E	ENSOCUP00000023951	ENSOCUP00000025873	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat containing 8 VRAC subunit E.	0.743