(11 nodes) calcineurin-NFAT signaling cascade network (Oryctolagus cuniculus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NFATC1	RHD domain-containing protein. (672 aa)
	NFATC3	Nuclear factor of activated T cells 3. (1070 aa)
	RCAN1	Regulator of calcineurin 1. (197 aa)
	MEF2D	Myocyte enhancer factor 2D. (517 aa)
	MEF2A	Myocyte enhancer factor 2A. (511 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (518 aa)
	G1TTB9_RABIT	Uncharacterized protein. (200 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (574 aa)
	NFATC4	Nuclear factor of activated T cells 4. (933 aa)
	NFATC2	Nuclear factor of activated T cells 2. (900 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (695 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G1TTB9_RABIT	NFATC1	ENSOCUP00000020289	ENSOCUP00000005601	Uncharacterized protein.	RHD domain-containing protein.	0.939
G1TTB9_RABIT	NFATC2	ENSOCUP00000020289	ENSOCUP00000044727	Uncharacterized protein.	Nuclear factor of activated T cells 2.	0.721
G1TTB9_RABIT	NFATC3	ENSOCUP00000020289	ENSOCUP00000008660	Uncharacterized protein.	Nuclear factor of activated T cells 3.	0.784
G1TTB9_RABIT	NFATC4	ENSOCUP00000020289	ENSOCUP00000030284	Uncharacterized protein.	Nuclear factor of activated T cells 4.	0.489
G1TTB9_RABIT	PPP3CA	ENSOCUP00000020289	ENSOCUP00000045121	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.987
G1TTB9_RABIT	PPP3CB	ENSOCUP00000020289	ENSOCUP00000019808	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.972
G1TTB9_RABIT	PPP3CC	ENSOCUP00000020289	ENSOCUP00000028255	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.956
G1TTB9_RABIT	RCAN1	ENSOCUP00000020289	ENSOCUP00000009139	Uncharacterized protein.	Regulator of calcineurin 1.	0.758
MEF2A	MEF2D	ENSOCUP00000018692	ENSOCUP00000010475	Myocyte enhancer factor 2A.	Myocyte enhancer factor 2D.	0.978
MEF2A	NFATC1	ENSOCUP00000018692	ENSOCUP00000005601	Myocyte enhancer factor 2A.	RHD domain-containing protein.	0.917
MEF2A	NFATC2	ENSOCUP00000018692	ENSOCUP00000044727	Myocyte enhancer factor 2A.	Nuclear factor of activated T cells 2.	0.920
MEF2A	NFATC3	ENSOCUP00000018692	ENSOCUP00000008660	Myocyte enhancer factor 2A.	Nuclear factor of activated T cells 3.	0.910
MEF2A	NFATC4	ENSOCUP00000018692	ENSOCUP00000030284	Myocyte enhancer factor 2A.	Nuclear factor of activated T cells 4.	0.928
MEF2D	MEF2A	ENSOCUP00000010475	ENSOCUP00000018692	Myocyte enhancer factor 2D.	Myocyte enhancer factor 2A.	0.978
MEF2D	NFATC1	ENSOCUP00000010475	ENSOCUP00000005601	Myocyte enhancer factor 2D.	RHD domain-containing protein.	0.933
MEF2D	NFATC2	ENSOCUP00000010475	ENSOCUP00000044727	Myocyte enhancer factor 2D.	Nuclear factor of activated T cells 2.	0.930
MEF2D	NFATC3	ENSOCUP00000010475	ENSOCUP00000008660	Myocyte enhancer factor 2D.	Nuclear factor of activated T cells 3.	0.924
MEF2D	NFATC4	ENSOCUP00000010475	ENSOCUP00000030284	Myocyte enhancer factor 2D.	Nuclear factor of activated T cells 4.	0.915
NFATC1	G1TTB9_RABIT	ENSOCUP00000005601	ENSOCUP00000020289	RHD domain-containing protein.	Uncharacterized protein.	0.939
NFATC1	MEF2A	ENSOCUP00000005601	ENSOCUP00000018692	RHD domain-containing protein.	Myocyte enhancer factor 2A.	0.917