(31 nodes) COPII vesicle coat, and DDHD domain network (Oryctolagus cuniculus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SEC23IP	SEC23 interacting protein. (999 aa)
	SAR1A	Secretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	SEC16B	Protein transport protein Sec16B; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes; Belongs to the SEC16 family. (1052 aa)
	PEF1	Penta-EF-hand domain containing 1. (277 aa)
	PREB	Prolactin regulatory element binding. (418 aa)
	LOC100349893	Uncharacterized protein; Belongs to the tropomyosin family. (205 aa)
	MCFD2	Uncharacterized protein. (305 aa)
	SEC24A	SEC24 homolog A, COPII coat complex component. (1091 aa)
	KLHL12	Kelch like family member 12. (851 aa)
	SEC23A	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)
	SEC13	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (468 aa)
	LMAN1L	Lectin, mannose binding 1 like. (526 aa)
	SEC24D	SEC24 homolog D, COPII coat complex component. (979 aa)
	SEC23B	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (767 aa)
	ANKRD40	Ankyrin repeat domain 40. (365 aa)
	PDCD6	Programmed cell death 6. (191 aa)
	FAM222A	Family with sequence similarity 222 member A. (456 aa)
	DDHD2	DDHD domain containing 2. (714 aa)
	LMAN1	Lectin, mannose binding 1. (518 aa)
	TFG	Trafficking from ER to golgi regulator. (401 aa)
	SEC31A	SEC31 homolog A, COPII coat complex component. (1263 aa)
	ENSOCUP00000028080	Uncharacterized protein. (115 aa)
	SEC24B	SEC24 homolog B, COPII coat complex component. (1229 aa)
	GALNT7	Polypeptide N-acetylgalactosaminyltransferase. (633 aa)
	ENSOCUP00000030867	DDHD domain-containing protein. (225 aa)
	DDHD1	DDHD domain-containing protein. (930 aa)
	SAR1B	Secretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (295 aa)
	SEC31B	SEC31 homolog B, COPII coat complex component. (1182 aa)
	ENSOCUP00000045050	DDHD domain-containing protein. (214 aa)
	SEC24C	Uncharacterized protein. (1025 aa)
	F8	Coagulation factor VIII isoform a (Predicted); Belongs to the multicopper oxidase family. (2336 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD40	DDHD1	ENSOCUP00000018024	ENSOCUP00000043189	Ankyrin repeat domain 40.	DDHD domain-containing protein.	0.451
ANKRD40	DDHD2	ENSOCUP00000018024	ENSOCUP00000023596	Ankyrin repeat domain 40.	DDHD domain containing 2.	0.451
ANKRD40	ENSOCUP00000028080	ENSOCUP00000018024	ENSOCUP00000028080	Ankyrin repeat domain 40.	Uncharacterized protein.	0.771
ANKRD40	ENSOCUP00000030867	ENSOCUP00000018024	ENSOCUP00000030867	Ankyrin repeat domain 40.	DDHD domain-containing protein.	0.451
ANKRD40	ENSOCUP00000045050	ENSOCUP00000018024	ENSOCUP00000045050	Ankyrin repeat domain 40.	DDHD domain-containing protein.	0.451
ANKRD40	LMAN1	ENSOCUP00000018024	ENSOCUP00000024695	Ankyrin repeat domain 40.	Lectin, mannose binding 1.	0.565
ANKRD40	LMAN1L	ENSOCUP00000018024	ENSOCUP00000010214	Ankyrin repeat domain 40.	Lectin, mannose binding 1 like.	0.565
ANKRD40	MCFD2	ENSOCUP00000018024	ENSOCUP00000006725	Ankyrin repeat domain 40.	Uncharacterized protein.	0.491
ANKRD40	PREB	ENSOCUP00000018024	ENSOCUP00000005638	Ankyrin repeat domain 40.	Prolactin regulatory element binding.	0.422
ANKRD40	SAR1A	ENSOCUP00000018024	ENSOCUP00000003921	Ankyrin repeat domain 40.	Secretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family.	0.771
ANKRD40	SAR1B	ENSOCUP00000018024	ENSOCUP00000043297	Ankyrin repeat domain 40.	Secretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family.	0.771
ANKRD40	SEC13	ENSOCUP00000018024	ENSOCUP00000009214	Ankyrin repeat domain 40.	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.	0.922
ANKRD40	SEC16B	ENSOCUP00000018024	ENSOCUP00000004518	Ankyrin repeat domain 40.	Protein transport protein Sec16B; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes; Belongs to the SEC16 family.	0.829
ANKRD40	SEC23A	ENSOCUP00000018024	ENSOCUP00000008549	Ankyrin repeat domain 40.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.853
ANKRD40	SEC23B	ENSOCUP00000018024	ENSOCUP00000012963	Ankyrin repeat domain 40.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.853
ANKRD40	SEC23IP	ENSOCUP00000018024	ENSOCUP00000002731	Ankyrin repeat domain 40.	SEC23 interacting protein.	0.451
ANKRD40	SEC24A	ENSOCUP00000018024	ENSOCUP00000007143	Ankyrin repeat domain 40.	SEC24 homolog A, COPII coat complex component.	0.870
ANKRD40	SEC24B	ENSOCUP00000018024	ENSOCUP00000030158	Ankyrin repeat domain 40.	SEC24 homolog B, COPII coat complex component.	0.870
ANKRD40	SEC24C	ENSOCUP00000018024	ENSOCUP00000047804	Ankyrin repeat domain 40.	Uncharacterized protein.	0.735
ANKRD40	SEC24D	ENSOCUP00000018024	ENSOCUP00000011427	Ankyrin repeat domain 40.	SEC24 homolog D, COPII coat complex component.	0.735