(5 nodes) Heavy-metal-associated domain network (Oryctolagus cuniculus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCS	Copper chaperone for superoxide dismutase. (274 aa)
	ATP7A	ATPase copper transporting alpha. (1499 aa)
	MT4	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (62 aa)
	ATP7B	ATPase copper transporting beta. (1465 aa)
	ATOX1	Antioxidant 1 copper chaperone. (68 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATOX1	ATP7A	ENSOCUP00000046347	ENSOCUP00000012171	Antioxidant 1 copper chaperone.	ATPase copper transporting alpha.	0.995
ATOX1	ATP7B	ENSOCUP00000046347	ENSOCUP00000043559	Antioxidant 1 copper chaperone.	ATPase copper transporting beta.	0.992
ATOX1	CCS	ENSOCUP00000046347	ENSOCUP00000011889	Antioxidant 1 copper chaperone.	Copper chaperone for superoxide dismutase.	0.939
ATOX1	MT4	ENSOCUP00000046347	ENSOCUP00000014837	Antioxidant 1 copper chaperone.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.794
ATP7A	ATOX1	ENSOCUP00000012171	ENSOCUP00000046347	ATPase copper transporting alpha.	Antioxidant 1 copper chaperone.	0.995
ATP7A	ATP7B	ENSOCUP00000012171	ENSOCUP00000043559	ATPase copper transporting alpha.	ATPase copper transporting beta.	0.905
ATP7A	CCS	ENSOCUP00000012171	ENSOCUP00000011889	ATPase copper transporting alpha.	Copper chaperone for superoxide dismutase.	0.996
ATP7A	MT4	ENSOCUP00000012171	ENSOCUP00000014837	ATPase copper transporting alpha.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.728
ATP7B	ATOX1	ENSOCUP00000043559	ENSOCUP00000046347	ATPase copper transporting beta.	Antioxidant 1 copper chaperone.	0.992
ATP7B	ATP7A	ENSOCUP00000043559	ENSOCUP00000012171	ATPase copper transporting beta.	ATPase copper transporting alpha.	0.905
ATP7B	CCS	ENSOCUP00000043559	ENSOCUP00000011889	ATPase copper transporting beta.	Copper chaperone for superoxide dismutase.	0.994
ATP7B	MT4	ENSOCUP00000043559	ENSOCUP00000014837	ATPase copper transporting beta.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.741
CCS	ATOX1	ENSOCUP00000011889	ENSOCUP00000046347	Copper chaperone for superoxide dismutase.	Antioxidant 1 copper chaperone.	0.939
CCS	ATP7A	ENSOCUP00000011889	ENSOCUP00000012171	Copper chaperone for superoxide dismutase.	ATPase copper transporting alpha.	0.996
CCS	ATP7B	ENSOCUP00000011889	ENSOCUP00000043559	Copper chaperone for superoxide dismutase.	ATPase copper transporting beta.	0.994
CCS	MT4	ENSOCUP00000011889	ENSOCUP00000014837	Copper chaperone for superoxide dismutase.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.738
MT4	ATOX1	ENSOCUP00000014837	ENSOCUP00000046347	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Antioxidant 1 copper chaperone.	0.794
MT4	ATP7A	ENSOCUP00000014837	ENSOCUP00000012171	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	ATPase copper transporting alpha.	0.728
MT4	ATP7B	ENSOCUP00000014837	ENSOCUP00000043559	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	ATPase copper transporting beta.	0.741
MT4	CCS	ENSOCUP00000014837	ENSOCUP00000011889	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Copper chaperone for superoxide dismutase.	0.738