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HNRNPC | Heterogeneous nuclear ribonucleoprotein C; Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilit [...] (306 aa) | ||||
HNRNPD | Heterogeneous nuclear ribonucleoprotein D. (286 aa) | ||||
HNRNPR | Heterogeneous nuclear ribonucleoprotein R. (635 aa) | ||||
HNRNPK | Heterogeneous nuclear ribonucleoprotein K; One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is co [...] (463 aa) | ||||
HNRNPA1 | Uncharacterized protein. (371 aa) | ||||
HNRNPA2B1 | Heterogeneous nuclear ribonucleoprotein A2/B1. (352 aa) | ||||
HNRNPL | Heterogeneous nuclear ribonucleoprotein L; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa) | ||||
HNRNPF | Uncharacterized protein. (543 aa) | ||||
HNRNPH1 | Heterogeneous nuclear ribonucleoprotein H1. (591 aa) | ||||
HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (844 aa) |