STRINGSTRING
TAF11 TAF11 ERCC3 ERCC3 GTF2E1 GTF2E1 CCNC CCNC MED29 MED29 GTF2H3 GTF2H3 GTF2F2 GTF2F2 TAF12 TAF12 TAF7L TAF7L CCNH CCNH DDX11 DDX11 TAF5 TAF5 TAF10 TAF10 MED13 MED13 MED9 MED9 CDK7 CDK7 PLPPR4 PLPPR4 POLR2G POLR2G MED8 MED8 GTF2A2 GTF2A2 MED30 MED30 POLR2F POLR2F MED4 MED4 MED17 MED17 MED27 MED27 PLPPR1 PLPPR1 TAF7 TAF7 MNAT1 MNAT1 CDK19 CDK19 TAF9B TAF9B POLR2C POLR2C CDK8 CDK8 LOC100338745 LOC100338745 GTF2E2 GTF2E2 POLR2B POLR2B MED31 MED31 POLR2K-2 POLR2K-2 MED20 MED20 GTF2H1 GTF2H1 MED8-2 MED8-2 POLR2J POLR2J PLPPR2 PLPPR2 MED25 MED25 TAF6 TAF6 PRR30 PRR30 LOC100342427 LOC100342427 MED10 MED10 GTF2F1 GTF2F1 POLR2I POLR2I MED1 MED1 EZHIP EZHIP TAF3 TAF3 G1TWQ7_RABIT G1TWQ7_RABIT TBP TBP POLR2D POLR2D GTF2H5 GTF2H5 G1U6U0_RABIT G1U6U0_RABIT MED14 MED14 TAF4B TAF4B MED15 MED15 ERCC2 ERCC2 C11orf88 C11orf88 MED19 MED19 ENSOCUP00000031335 ENSOCUP00000031335 ENSOCUP00000032325 ENSOCUP00000032325 CYP3A6 CYP3A6 MED26 MED26 TAF13 TAF13 ENSOCUP00000037069 ENSOCUP00000037069 ENSOCUP00000038037 ENSOCUP00000038037 MED13L MED13L GTF2H4 GTF2H4 MED12L MED12L FBXW12 FBXW12 MED23 MED23 MED24 MED24 ENSOCUP00000043713 ENSOCUP00000043713 ENSOCUP00000044058 ENSOCUP00000044058 MED6 MED6 TAF2 TAF2 TAF1 TAF1 ENSOCUP00000047029 ENSOCUP00000047029 ENSOCUP00000047065 ENSOCUP00000047065 GTF2A1L GTF2A1L MED21 MED21 MED12 MED12 TAF8 TAF8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TAF11TAFII28 domain-containing protein. (211 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
GTF2E1General transcription factor IIE subunit 1. (438 aa)
CCNCCyclin C; Belongs to the cyclin family. (283 aa)
MED29Mediator complex subunit 29. (194 aa)
GTF2H3General transcription factor IIH subunit 3. (309 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (318 aa)
TAF12TATA-box binding protein associated factor 12. (161 aa)
TAF7LTAFII55_N domain-containing protein. (302 aa)
CCNHCyclin H; Belongs to the cyclin family. (323 aa)
DDX11Helicase ATP-binding domain-containing protein. (330 aa)
TAF5TATA-box binding protein associated factor 5. (799 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
MED13Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2156 aa)
MED9Uncharacterized protein. (75 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
PLPPR4Phospholipid phosphatase related 4. (762 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (124 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
MED30Mediator complex subunit 30. (178 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
MED17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (608 aa)
MED27Mediator complex subunit 27. (409 aa)
PLPPR1Phospholipid phosphatase related 1. (325 aa)
TAF7TATA-box binding protein associated factor 7. (349 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
CDK19Cyclin dependent kinase 19. (502 aa)
TAF9BTATA-box binding protein associated factor 9b. (251 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
CDK8Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
LOC100338745VWFA domain-containing protein. (360 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (257 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
POLR2K-2Uncharacterized protein. (58 aa)
MED20Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (212 aa)
GTF2H1Uncharacterized protein. (545 aa)
MED8-2Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (415 aa)
POLR2JRNA polymerase II subunit J. (117 aa)
PLPPR2Phospholipid phosphatase related 2. (376 aa)
MED25Mediator complex subunit 25. (658 aa)
TAF6TATA-box binding protein associated factor 6. (722 aa)
PRR30Uncharacterized protein. (286 aa)
LOC100342427Uncharacterized protein. (204 aa)
MED10Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (71 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (234 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1580 aa)
EZHIPUncharacterized protein. (594 aa)
TAF3TATA-box binding protein associated factor 3. (930 aa)
G1TWQ7_RABITTAFH domain-containing protein. (562 aa)
TBPTATA-box binding protein. (323 aa)
POLR2DRPOL4c domain-containing protein. (110 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
G1U6U0_RABITBSD domain-containing protein. (165 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1331 aa)
TAF4BTATA-box binding protein associated factor 4b. (837 aa)
MED15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (752 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (805 aa)
C11orf88Chromosome 11 open reading frame 88. (185 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (288 aa)
ENSOCUP00000031335TFIID_20kDa domain-containing protein. (217 aa)
ENSOCUP00000032325RPOL4c domain-containing protein. (146 aa)
CYP3A6Cytochrome P450 3A6; Exhibits progesterone 6 beta-hydroxylase activity. (537 aa)
MED26TFS2N domain-containing protein. (907 aa)
TAF13TATA-box binding protein associated factor 13. (124 aa)
ENSOCUP00000037069Uncharacterized protein. (233 aa)
ENSOCUP00000038037TFIIA_gamma_C domain-containing protein. (80 aa)
MED13LMediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2254 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (503 aa)
MED12LMediator complex subunit 12L. (2151 aa)
FBXW12F-box and WD repeat domain containing 12. (463 aa)
MED23Mediator complex subunit 23. (1552 aa)
MED24Mediator complex subunit 24. (1010 aa)
ENSOCUP00000043713Uncharacterized protein. (329 aa)
ENSOCUP00000044058RPOL9 domain-containing protein. (195 aa)
MED6Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (252 aa)
TAF2TATA-box binding protein associated factor 2. (1261 aa)
TAF1Transcription initiation factor TFIID subunit. (1878 aa)
ENSOCUP00000047029TAFII28 domain-containing protein. (196 aa)
ENSOCUP00000047065Uncharacterized protein. (604 aa)
GTF2A1LUncharacterized protein. (564 aa)
MED21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (144 aa)
MED12Mediator complex subunit 12. (2142 aa)
TAF8TATA-box binding protein associated factor 8. (377 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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