STRINGSTRING
KATNBL1 KATNBL1 WDR73 WDR73 AURKA AURKA WDR62 WDR62 G1TGL8_RABIT G1TGL8_RABIT ANKRD53 ANKRD53 G1TKH4_RABIT G1TKH4_RABIT TUBGCP6 TUBGCP6 TPT1 TPT1 RASSF10 RASSF10 G1TSB1_RABIT G1TSB1_RABIT G1TUF4_RABIT G1TUF4_RABIT BRCC3 BRCC3 SGO2 SGO2 ZW10 ZW10 G1TXH2_RABIT G1TXH2_RABIT RASSF1 RASSF1 MAP10 MAP10 UNC119 UNC119 PLK3 PLK3 PRC1 PRC1 KATNB1 KATNB1 RAE1 RAE1 ENSOCUP00000039364 ENSOCUP00000039364 KIF11 KIF11 KNSTRN KNSTRN CDC14B CDC14B SBDS SBDS AUNIP AUNIP KAT5 KAT5 ENSOCUP00000037603 ENSOCUP00000037603 RMDN3 RMDN3 CEP128 CEP128 ENSOCUP00000036030 ENSOCUP00000036030 ENSOCUP00000035544 ENSOCUP00000035544 ENSOCUP00000035121 ENSOCUP00000035121 FAM110A FAM110A CEP63 CEP63 ODF2 ODF2 ALPK1 ALPK1 UMOD UMOD FRY FRY ENSOCUP00000033468 ENSOCUP00000033468 CTNNB1 CTNNB1 HSF1 HSF1 MAD1L1 MAD1L1 CUL3 CUL3 TUBGCP3 TUBGCP3 NEK6 NEK6 UBXN2B UBXN2B AURKB AURKB TTC28 TTC28 ENSOCUP00000029906 ENSOCUP00000029906 NDE1 NDE1 TBCCD1 TBCCD1 ENSOCUP00000027926 ENSOCUP00000027926 RAB11B RAB11B RMDN1 RMDN1 MAPRE1 MAPRE1 G1U6R3_RABIT G1U6R3_RABIT NUMA1 NUMA1 ENSOCUP00000049983 ENSOCUP00000049983 MTCL1 MTCL1 LATS1 LATS1 LOC100353956 LOC100353956 DCTN4 DCTN4 CEP89 CEP89 LATS2 LATS2 CALM2 CALM2 SPOUT1 SPOUT1 ENSOCUP00000047190 ENSOCUP00000047190 ENSOCUP00000046174 ENSOCUP00000046174 SPDL1 SPDL1 ENSOCUP00000045898 ENSOCUP00000045898 VPS4A VPS4A ENSOCUP00000045093 ENSOCUP00000045093 CTDP1 CTDP1 CEP44 CEP44 HNRNPU HNRNPU LOC100357892 LOC100357892 KATNAL2 KATNAL2 ALMS1 ALMS1 CDC14A CDC14A ENSOCUP00000041847 ENSOCUP00000041847 SMC1A SMC1A DYNC1LI1 DYNC1LI1 RMDN2 RMDN2 EFCAB13 EFCAB13 FAM110C FAM110C FAM161A FAM161A TUBGCP2 TUBGCP2 CEP104 CEP104 EFCAB3 EFCAB3 POC1A POC1A KIF20B KIF20B DLGAP5 DLGAP5 TPX2 TPX2 KATNAL1 KATNAL1 GPSM2 GPSM2 TMEM201 TMEM201 ABRAXAS2 ABRAXAS2 CDC6 CDC6 PLK4 PLK4 TOPORS TOPORS NUDCD2 NUDCD2 SGO1 SGO1 DDX11 DDX11 BIRC6 BIRC6 PLK2 PLK2 POC1B POC1B MAD2L1 MAD2L1 PLK1 PLK1 BCCIP BCCIP BOD1L1 BOD1L1 NEK2 NEK2 STAG2 STAG2 RALBP1 RALBP1 UXT UXT TUBGCP5 TUBGCP5 KATNA1 KATNA1 NEDD1 NEDD1 CCDC155 CCDC155 SMC3 SMC3 AAAS AAAS AURKC AURKC NEK7 NEK7 CALM1 CALM1 MAPKBP1 MAPKBP1 EFHC1 EFHC1 DYNC1I1 DYNC1I1 CALML5 CALML5 STAG1 STAG1 CEP95 CEP95 TOPBP1 TOPBP1 RGS14 RGS14 ABRAXAS1 ABRAXAS1 PKP4 PKP4 YPEL5 YPEL5 G1T5U0_RABIT G1T5U0_RABIT CDC25B CDC25B SPAG5 SPAG5 KNTC1 KNTC1 BOD1 BOD1 ASPM ASPM DCTN1 DCTN1 NEDD9 NEDD9 NIN NIN PSRC1 PSRC1 CSPP1 CSPP1 PPP2CA PPP2CA LRMP LRMP G1TAZ6_RABIT G1TAZ6_RABIT CKAP5 CKAP5 GIT1 GIT1 CEP85 CEP85 CEP19 CEP19 SMC6 SMC6 TUBGCP4 TUBGCP4 HAUS1 HAUS1 TNKS TNKS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KATNBL1Katanin regulatory subunit B1 like 1. (304 aa)
WDR73WD repeat domain 73. (372 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (402 aa)
WDR62WD repeat domain 62. (1534 aa)
G1TGL8_RABITTCTP domain-containing protein; Belongs to the TCTP family. (170 aa)
ANKRD53Ankyrin repeat domain 53. (468 aa)
G1TKH4_RABITUncharacterized protein. (333 aa)
TUBGCP6Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (662 aa)
TPT1Translationally-controlled tumor protein; Involved in calcium binding and microtubule stabilization. Belongs to the TCTP family. (191 aa)
RASSF10Ras association domain family member 10. (426 aa)
G1TSB1_RABITSerine/threonine-protein phosphatase. (282 aa)
G1TUF4_RABITSER_THR_PHOSPHATASE domain-containing protein. (215 aa)
BRCC3BRCA1/BRCA2-containing complex subunit 3. (291 aa)
SGO2Uncharacterized protein. (341 aa)
ZW10Zw10 kinetochore protein. (864 aa)
G1TXH2_RABITUncharacterized protein. (569 aa)
RASSF1Uncharacterized protein. (189 aa)
MAP10Microtubule associated protein 10. (832 aa)
UNC119Unc-119 lipid binding chaperone. (145 aa)
PLK3Serine/threonine-protein kinase PLK. (647 aa)
PRC1Protein regulator of cytokinesis 1. (612 aa)
KATNB1Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] (655 aa)
RAE1Ribonucleic acid export 1. (400 aa)
ENSOCUP00000039364Protein kinase domain-containing protein. (328 aa)
KIF11Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1092 aa)
KNSTRNKinetochore localized astrin (SPAG5) binding protein. (227 aa)
CDC14BUncharacterized protein. (560 aa)
SBDSSBDS ribosome maturation factor. (263 aa)
AUNIPAurora kinase A and ninein interacting protein. (400 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (620 aa)
ENSOCUP00000037603annotation not available (172 aa)
RMDN3Regulator of microtubule dynamics 3. (493 aa)
CEP128Centrosomal protein 128. (1143 aa)
ENSOCUP00000036030TCTP domain-containing protein; Belongs to the TCTP family. (236 aa)
ENSOCUP00000035544Uncharacterized protein; Belongs to the AAA ATPase family. (399 aa)
ENSOCUP00000035121Serine/threonine-protein phosphatase. (279 aa)
FAM110AFamily with sequence similarity 110 member A. (380 aa)
CEP63Centrosomal protein 63. (708 aa)
ODF2Outer dense fiber of sperm tails 2. (884 aa)
ALPK1Alpha kinase 1. (1246 aa)
UMODUromodulin. (794 aa)
FRYFRY microtubule binding protein. (3057 aa)
ENSOCUP00000033468Uncharacterized protein. (117 aa)
CTNNB1Catenin beta 1. (741 aa)
HSF1Heat shock transcription factor 1. (680 aa)
MAD1L1Uncharacterized protein. (434 aa)
CUL3Cullin 3; Belongs to the cullin family. (771 aa)
TUBGCP3Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (859 aa)
NEK6Protein kinase domain-containing protein. (547 aa)
UBXN2BUBX domain protein 2B. (391 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (404 aa)
TTC28Tetratricopeptide repeat domain 28. (2364 aa)
ENSOCUP00000029906SMC hinge domain-containing protein. (685 aa)
NDE1NudE neurodevelopment protein 1. (396 aa)
TBCCD1TBCC domain containing 1. (591 aa)
ENSOCUP00000027926Uncharacterized protein. (94 aa)
RAB11BRas-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] (312 aa)
RMDN1Regulator of microtubule dynamics 1. (327 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (268 aa)
G1U6R3_RABITUncharacterized protein. (670 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2116 aa)
ENSOCUP00000049983Uncharacterized protein. (319 aa)
MTCL1Microtubule crosslinking factor 1. (1660 aa)
LATS1Large tumor suppressor kinase 1. (1124 aa)
LOC100353956TCTP domain-containing protein; Belongs to the TCTP family. (162 aa)
DCTN4Dynactin subunit 4. (467 aa)
CEP89Centrosomal protein 89. (778 aa)
LATS2Large tumor suppressor kinase 2. (1142 aa)
CALM2Uncharacterized protein; Belongs to the calmodulin family. (153 aa)
SPOUT1Uncharacterized protein. (389 aa)
ENSOCUP00000047190TCTP domain-containing protein; Belongs to the TCTP family. (236 aa)
ENSOCUP00000046174Uncharacterized protein. (116 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (621 aa)
ENSOCUP00000045898Protein kinase domain-containing protein. (192 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (747 aa)
ENSOCUP00000045093BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (315 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (846 aa)
CEP44Centrosomal protein 44. (441 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (844 aa)
LOC100357892TCTP domain-containing protein; Belongs to the TCTP family. (178 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (594 aa)
ALMS1ALMS1 centrosome and basal body associated protein. (4165 aa)
CDC14ACell division cycle 14A. (625 aa)
ENSOCUP00000041847Uncharacterized protein; Belongs to the calmodulin family. (77 aa)
SMC1ASMC hinge domain-containing protein. (1158 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (586 aa)
RMDN2Uncharacterized protein. (547 aa)
EFCAB13EF-hand calcium binding domain 13. (788 aa)
FAM110CFamily with sequence similarity 110 member C. (303 aa)
FAM161AUncharacterized protein. (601 aa)
TUBGCP2Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (905 aa)
CEP104Centrosomal protein 104. (683 aa)
EFCAB3EF-hand calcium binding domain 3. (473 aa)
POC1APOC1 centriolar protein A. (406 aa)
KIF20BKinesin family member 20B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1758 aa)
DLGAP5DLG associated protein 5. (826 aa)
TPX2TPX2 microtubule nucleation factor. (819 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity). Has microtubule- severing activity in vitro (By similarity). Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily. (497 aa)
GPSM2Uncharacterized protein. (684 aa)
TMEM201Transmembrane protein 201. (667 aa)
ABRAXAS2Abraxas 2, BRISC complex subunit. (440 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (560 aa)
PLK4Polo like kinase 4. (969 aa)
TOPORSTOP1 binding arginine/serine rich protein. (1103 aa)
NUDCD2NudC domain containing 2. (157 aa)
SGO1Shugoshin 1. (540 aa)
DDX11Helicase ATP-binding domain-containing protein. (330 aa)
BIRC6Baculoviral IAP repeat containing 6. (4863 aa)
PLK2Serine/threonine-protein kinase PLK. (666 aa)
POC1BPOC1 centriolar protein B. (477 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
BCCIPBRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (315 aa)
BOD1L1Biorientation of chromosomes in cell division 1 like 1. (2960 aa)
NEK2NIMA related kinase 2. (451 aa)
STAG2Stromal antigen 2 isoform a (Predicted). (1268 aa)
RALBP1RalA binding protein 1. (643 aa)
UXTUbiquitously expressed prefoldin like chaperone. (157 aa)
TUBGCP5Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (1026 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (506 aa)
NEDD1NEDD1 gamma-tubulin ring complex targeting factor. (667 aa)
CCDC155Uncharacterized protein. (332 aa)
SMC3Structural maintenance of chromosomes protein. (1244 aa)
AAASAladin WD repeat nucleoporin. (546 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (292 aa)
NEK7Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (326 aa)
CALM1Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). (149 aa)
MAPKBP1Mitogen-activated protein kinase binding protein 1. (1231 aa)
EFHC1EF-hand domain containing 1. (624 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (653 aa)
CALML5Calmodulin like 5. (149 aa)
STAG1Stromal antigen 1. (1258 aa)
CEP95Centrosomal protein 95. (870 aa)
TOPBP1DNA topoisomerase II binding protein 1. (1546 aa)
RGS14Regulator of G protein signaling 14. (552 aa)
ABRAXAS1Abraxas 1, BRCA1 A complex subunit. (409 aa)
PKP4Plakophilin 4. (1191 aa)
YPEL5Protein yippee-like; Belongs to the yippee family. (121 aa)
G1T5U0_RABITUncharacterized protein. (944 aa)
CDC25BCell division cycle 25B. (413 aa)
SPAG5Sperm associated antigen 5. (1177 aa)
KNTC1Kinetochore associated 1. (2195 aa)
BOD1Uncharacterized protein. (281 aa)
ASPMUncharacterized protein. (1883 aa)
DCTN1CAP-Gly domain-containing protein. (1265 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (828 aa)
NINNinein. (2216 aa)
PSRC1Proline and serine rich coiled-coil 1. (363 aa)
CSPP1Centrosome and spindle pole associated protein 1. (1216 aa)
PPP2CASerine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). (309 aa)
LRMPLymphoid restricted membrane protein. (500 aa)
G1TAZ6_RABITUncharacterized protein. (396 aa)
CKAP5Cytoskeleton associated protein 5. (2034 aa)
GIT1GIT ArfGAP 1. (753 aa)
CEP85Centrosomal protein 85. (711 aa)
CEP19Centrosomal protein 19. (163 aa)
SMC6Uncharacterized protein. (927 aa)
TUBGCP4Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (667 aa)
HAUS1HAUS augmin like complex subunit 1. (300 aa)
TNKSPoly [ADP-ribose] polymerase. (1326 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (18%) [HD]