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CA9 | Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. (435 aa) | ||||
ADA | Adenosine deaminase. (363 aa) | ||||
LMNA | Lamin A/C; Belongs to the intermediate filament family. (704 aa) | ||||
NOL3 | Nucleolar protein 3. (212 aa) | ||||
AK4 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa) | ||||
ADM | Adrenomedullin. (187 aa) | ||||
PPARA | Peroxisome proliferator activated receptor alpha. (503 aa) | ||||
ALKBH5 | AlkB homolog 5, RNA demethylase. (393 aa) | ||||
SCFD1 | Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (619 aa) | ||||
SLC11A2 | Solute carrier family 11 member 2. (589 aa) | ||||
G1SSI4_RABIT | GLOBIN domain-containing protein; Belongs to the globin family. (482 aa) | ||||
ENG | Endoglin. (758 aa) | ||||
ADAM15 | ADAM metallopeptidase domain 15. (881 aa) | ||||
BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (1212 aa) | ||||
PINK1 | PTEN induced kinase 1. (569 aa) | ||||
WDR83 | WD repeat domain 83. (315 aa) | ||||
STC1 | Stanniocalcin 1. (247 aa) | ||||
EPO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (195 aa) | ||||
PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) | ||||
TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) | ||||
IL18 | Uncharacterized protein. (408 aa) | ||||
NKX3-1 | NK3 homeobox 1. (159 aa) | ||||
HYOU1 | Hypoxia up-regulated 1. (999 aa) | ||||
KCND2 | Potassium voltage-gated channel subfamily D member 2; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in rodent heart. Mediates the major part of the dendritic A-type current I(SA) in brain neurons (By similarity). This current is activated at membrane potentials that are below the threshold for action potentials. It regulates neuronal excitability, prolongs the latency before the first spike in a series of action potentials, regulates the frequency of repetitive action potential firing, shortens t [...] (630 aa) | ||||
SMAD4 | Mothers against decapentaplegic homolog. (552 aa) | ||||
AGTRAP | Angiotensin II receptor associated protein. (159 aa) | ||||
SLC29A1 | Solute carrier family 29 member 1 (Augustine blood group). (456 aa) | ||||
SCAP | SREBF chaperone. (1279 aa) | ||||
SRF | Serum response factor. (685 aa) | ||||
STOX1 | Storkhead box 1. (977 aa) | ||||
FAM162A | Family with sequence similarity 162 member A. (155 aa) | ||||
CHRNA7 | Uncharacterized protein. (513 aa) | ||||
BNIP3 | BCL2 interacting protein 3. (218 aa) | ||||
RYR2 | Ryanodine receptor 2; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. Required for cellular calcium ion homeostasis. Required for embryonic heart development (By similarity). The calcium channel activity is modulated by formation of heterotetramers with RYR3; Belongs to t [...] (4965 aa) | ||||
PML | Promyelocytic leukemia. (860 aa) | ||||
NDNF | Neuron derived neurotrophic factor. (643 aa) | ||||
TIGAR | TP53 induced glycolysis regulatory phosphatase. (265 aa) | ||||
CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (366 aa) | ||||
NOS2 | Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1146 aa) | ||||
TBL2 | Transducin beta like 2. (446 aa) | ||||
REST | RE1 silencing transcription factor. (930 aa) | ||||
PAM | Peptidylglycine alpha-amidating monooxygenase. (975 aa) | ||||
PLOD2 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (762 aa) | ||||
EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (391 aa) | ||||
LOC100347410 | Uncharacterized protein. (155 aa) | ||||
OPRD1 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (373 aa) | ||||
PRKAA1 | Non-specific serine/threonine protein kinase. (656 aa) | ||||
PDK1 | Protein-serine/threonine kinase. (396 aa) | ||||
G1SCK7_RABIT | Uncharacterized protein; Belongs to the cytochrome P450 family. (765 aa) | ||||
MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (491 aa) | ||||
NF1 | Neurofibromin 1. (2841 aa) | ||||
EGLN3 | Fe2OG dioxygenase domain-containing protein. (456 aa) | ||||
G1SV95_RABIT | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) | ||||
EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (700 aa) | ||||
G1SV48_RABIT | Uncharacterized protein. (80 aa) | ||||
SLC2A8 | Solute carrier family 2 member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (477 aa) | ||||
CAMK2G | Protein kinase domain-containing protein. (592 aa) | ||||
ENSOCUP00000048569 | Uncharacterized protein. (108 aa) | ||||
MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (485 aa) | ||||
CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (249 aa) | ||||
CPEB2 | Cytoplasmic polyadenylation element binding protein 2. (698 aa) | ||||
ABAT | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (549 aa) | ||||
LOC100341256 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (85 aa) | ||||
PIN1 | Peptidyl-prolyl cis-trans isomerase. (224 aa) | ||||
PDK3 | Protein-serine/threonine kinase. (439 aa) | ||||
SLC8A3 | Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (958 aa) | ||||
ENSOCUP00000045925 | TGFb_propeptide domain-containing protein. (272 aa) | ||||
ADAM8 | ADAM metallopeptidase domain 8. (978 aa) | ||||
ENSOCUP00000045399 | Uncharacterized protein. (182 aa) | ||||
NDRG1 | N-myc downstream regulated 1. (438 aa) | ||||
BACH1 | BTB domain and CNC homolog 1. (719 aa) | ||||
ENSOCUP00000044284 | TGFb_propeptide domain-containing protein. (260 aa) | ||||
USF1 | Upstream stimulatory factor 1; Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters. Regulates the expression of the surfactant protein- A (SP-A) gene. (326 aa) | ||||
MPL | MPL proto-oncogene, thrombopoietin receptor. (635 aa) | ||||
FABP1 | FABP domain-containing protein. (194 aa) | ||||
ENSOCUP00000043082 | Uncharacterized protein. (319 aa) | ||||
LOXL3 | Lysyl oxidase like 3. (935 aa) | ||||
XRCC1 | X-ray repair cross complementing 1. (610 aa) | ||||
PLAT | Uncharacterized protein. (594 aa) | ||||
ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2735 aa) | ||||
ENSOCUP00000041840 | TGFb_propeptide domain-containing protein. (219 aa) | ||||
ENSOCUP00000041723 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (145 aa) | ||||
HIF1A | Uncharacterized protein. (851 aa) | ||||
NR4A2 | Nuclear receptor subfamily 4 group A member 2. (609 aa) | ||||
ENSOCUP00000040050 | LAG1_DNAbind domain-containing protein. (92 aa) | ||||
SIRT2 | Sirtuin 2. (509 aa) | ||||
EGLN2 | Egl-9 family hypoxia inducible factor 2. (501 aa) | ||||
GHRHR | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (524 aa) | ||||
ENSOCUP00000038975 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (85 aa) | ||||
HP1BP3 | Heterochromatin protein 1 binding protein 3. (570 aa) | ||||
PSEN2 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (539 aa) | ||||
HK2 | Hexokinase 2. (957 aa) | ||||
ENSOCUP00000037329 | TGFb_propeptide domain-containing protein. (263 aa) | ||||
LOXL4 | Lysyl oxidase like 4. (803 aa) | ||||
TXN2 | Thioredoxin 2. (166 aa) | ||||
HIF1AN | Hypoxia inducible factor 1 subunit alpha inhibitor. (371 aa) | ||||
BCL2 | BH4_2 domain-containing protein. (389 aa) | ||||
KCNK2 | Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (469 aa) | ||||
CYBB | FAD-binding FR-type domain-containing protein. (570 aa) | ||||
CHRNA4 | Cholinergic receptor nicotinic alpha 4 subunit. (620 aa) | ||||
ENSOCUP00000034930 | Protein-serine/threonine kinase. (195 aa) | ||||
MIEF1 | Mab-21 domain-containing protein. (600 aa) | ||||
SLC2A4 | MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (574 aa) | ||||
SLC8A1 | J domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa) | ||||
RORA | RAR related orphan receptor A. (512 aa) | ||||
HSF1 | Heat shock transcription factor 1. (680 aa) | ||||
LOC103345451 | TGFb_propeptide domain-containing protein. (203 aa) | ||||
ENSOCUP00000031376 | Uncharacterized protein. (95 aa) | ||||
RBPJ | Recombination signal binding protein for immunoglobulin kappa J region. (499 aa) | ||||
ENSOCUP00000030729 | Uncharacterized protein. (69 aa) | ||||
LIMD1 | LIM domains containing 1. (693 aa) | ||||
ENSOCUP00000030584 | Uncharacterized protein. (513 aa) | ||||
TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) | ||||
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2756 aa) | ||||
IRAK1 | Interleukin 1 receptor associated kinase 1. (534 aa) | ||||
ENSOCUP00000029917 | Uncharacterized protein. (169 aa) | ||||
ITGA2 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1202 aa) | ||||
ENSOCUP00000029165 | SWIB domain-containing protein. (260 aa) | ||||
CPEB1 | RRM domain-containing protein. (653 aa) | ||||
ENSOCUP00000028473 | Mab-21 domain-containing protein. (169 aa) | ||||
P2RX3 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (410 aa) | ||||
PPARD | Uncharacterized protein. (420 aa) | ||||
UCP3 | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa) | ||||
VHL | Uncharacterized protein. (191 aa) | ||||
MST1 | Macrophage stimulating 1; Belongs to the peptidase S1 family. (773 aa) | ||||
ACAA2 | Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa) | ||||
SMAD3 | SMAD family member 3. (230 aa) | ||||
FUNDC1 | Uncharacterized protein. (155 aa) | ||||
NFE2L2 | Nuclear factor, erythroid 2 like 2. (677 aa) | ||||
G1U9D6_RABIT | Uncharacterized protein. (105 aa) | ||||
G1U940_RABIT | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (178 aa) | ||||
SCN2A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2006 aa) | ||||
RYR1 | Ryanodine receptor 1; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high- level exercise increases the open probability of the channel and leads to Ca(2+) leaking into the cytoplasm (By similarity). Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. [...] (4598 aa) | ||||
DNMT3A | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (843 aa) | ||||
NARF | Nuclear prelamin A recognition factor; Belongs to the NARF family. (409 aa) | ||||
MYOCD | Myocardin. (989 aa) | ||||
NPEPPS | Aminopeptidase. (921 aa) | ||||
PHB2 | Prohibitin. (299 aa) | ||||
G1U2E4_RABIT | Uncharacterized protein. (147 aa) | ||||
ARNT2 | Aryl hydrocarbon receptor nuclear translocator 2. (668 aa) | ||||
PLAU | Urokinase-type plasminogen activator short chain A; Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin; Belongs to the peptidase S1 family. (433 aa) | ||||
SIRT1 | Sirtuin 1. (748 aa) | ||||
ANGPT4 | Angiopoietin 4. (487 aa) | ||||
CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) | ||||
EPAS1 | Endothelial PAS domain protein 1. (902 aa) | ||||
FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) | ||||
ADIPOQ | C1q domain-containing protein. (244 aa) | ||||
LOC100346169 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa) | ||||
PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa) | ||||
DIO3 | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (342 aa) | ||||
KCNK3 | Potassium channel subfamily K member. (347 aa) | ||||
PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (996 aa) | ||||
G1TLX8_RABIT | RING-type domain-containing protein. (248 aa) | ||||
G1TLX0_RABIT | Protein-serine/threonine kinase. (145 aa) | ||||
MGARP | Mitochondria localized glutamic acid rich protein. (312 aa) | ||||
AGER | Advanced glycosylation end-product specific receptor. (401 aa) | ||||
PLOD1 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (727 aa) | ||||
ADO | 2-aminoethanethiol dioxygenase. (247 aa) | ||||
ACVRL1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (327 aa) | ||||
AJUBA | Uncharacterized protein. (122 aa) | ||||
VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa) | ||||
AQP3 | Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa) | ||||
VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) | ||||
P2RX2 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (511 aa) | ||||
TFRC | Transferrin receptor. (763 aa) | ||||
GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) | ||||
PTGS2 | Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...] (604 aa) | ||||
DDIT4 | DNA damage inducible transcript 4. (229 aa) | ||||
ANGPTL4 | Angiopoietin like 4. (411 aa) | ||||
HSP90B1 | Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. (802 aa) | ||||
TGFBR3 | Transforming growth factor beta receptor 3. (851 aa) | ||||
ANGPT2 | Angiopoietin 2. (496 aa) | ||||
SUV39H2 | Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (410 aa) | ||||
FNDC1 | Fibronectin type III domain containing 1. (1636 aa) | ||||
PKLR | Pyruvate kinase; Belongs to the pyruvate kinase family. (574 aa) | ||||
G1T8C0_RABIT | Uncharacterized protein. (311 aa) | ||||
ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) | ||||
CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) | ||||
NPPC | Uncharacterized protein. (351 aa) | ||||
ATP7A | ATPase copper transporting alpha. (1499 aa) | ||||
CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) | ||||
PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (744 aa) | ||||
UCN3 | Urocortin 3. (167 aa) | ||||
PDLIM1 | PDZ and LIM domain 1. (330 aa) | ||||
ALAS2 | 5-aminolevulinate synthase. (613 aa) | ||||
TM9SF4 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (654 aa) | ||||
EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (202 aa) | ||||
EGLN1 | Uncharacterized protein. (457 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2547 aa) | ||||
CRYAB | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions; Belongs to the small heat shock protein (HSP20) family. (175 aa) | ||||
ERO1A | Endoplasmic reticulum oxidoreductase 1 alpha. (492 aa) | ||||
UCP2 | Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa) | ||||
ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (498 aa) | ||||
RTN4 | Reticulon. (1110 aa) | ||||
APAF1 | Apoptotic peptidase activating factor 1. (1183 aa) | ||||
HILPDA | Hypoxia inducible lipid droplet associated. (64 aa) | ||||
DRD2 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa) | ||||
DDR2 | Discoidin domain receptor tyrosine kinase 2. (848 aa) | ||||
EP300 | E1A binding protein p300. (2418 aa) | ||||
TGFB3 | Transforming growth factor beta 3. (458 aa) | ||||
SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (331 aa) | ||||
FAM167A | Family with sequence similarity 167 member A. (217 aa) | ||||
HMOX1 | Heme oxygenase 1. (288 aa) | ||||
BNIP3L | BCL2 interacting protein 3 like. (219 aa) | ||||
ADAM17 | ADAM metallopeptidase domain 17. (827 aa) |