STRINGSTRING
EXT2 EXT2 MEF2C MEF2C AXIN2 AXIN2 ENSOCUP00000045925 ENSOCUP00000045925 SNX19 SNX19 ENSOCUP00000044284 ENSOCUP00000044284 BMPR1B BMPR1B RARG RARG ENSOCUP00000041840 ENSOCUP00000041840 PTH1R PTH1R HIF1A HIF1A RB1 RB1 WNT5B WNT5B SOX5 SOX5 CREB3L2 CREB3L2 CYTL1 CYTL1 MUSTN1 MUSTN1 ADAMTS7 ADAMTS7 ENSOCUP00000037873 ENSOCUP00000037873 ENSOCUP00000037329 ENSOCUP00000037329 BMPR2 BMPR2 TRIP11 TRIP11 FGF18 FGF18 GPLD1 GPLD1 NFIB NFIB ENSOCUP00000032595 ENSOCUP00000032595 COL11A1 COL11A1 ENSOCUP00000032400 ENSOCUP00000032400 LOC103345451 LOC103345451 SOX6 SOX6 ENSOCUP00000031395 ENSOCUP00000031395 TGFBR2 TGFBR2 IMPAD1 IMPAD1 ENSOCUP00000028861 ENSOCUP00000028861 SHOX2 SHOX2 CHSY1 CHSY1 IHH IHH SULF2 SULF2 SIX2 SIX2 SERPINH1 SERPINH1 OSR2 OSR2 SCUBE2 SCUBE2 WNT2B WNT2B TWSG1 TWSG1 BMPR1A BMPR1A SFRP2 SFRP2 COL11A2 COL11A2 G1TBJ9_RABIT G1TBJ9_RABIT EXT1 EXT1 COL3A1 COL3A1 IFT80 IFT80 NPPC NPPC RUNX1 RUNX1 COL2A1 COL2A1 MEX3C MEX3C EIF2AK3 EIF2AK3 MEF2D MEF2D ATF2 ATF2 ARID5A ARID5A ECM1 ECM1 RUNX2 RUNX2 BMP2 BMP2 SMPD3 SMPD3 BMP4 BMP4 CCN3 CCN3 GDF5 GDF5 WNT10B WNT10B G1SV95_RABIT G1SV95_RABIT MATN1 MATN1 GLI3 GLI3 ADAMTS12 ADAMTS12 OSR1 OSR1 ANXA6 ANXA6 COL27A1 COL27A1 SULF1 SULF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EXT2Exostosin glycosyltransferase 2. (1147 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
AXIN2Axin 2. (816 aa)
ENSOCUP00000045925TGFb_propeptide domain-containing protein. (272 aa)
SNX19Sorting nexin 19. (997 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
RARGUncharacterized protein. (415 aa)
ENSOCUP00000041840TGFb_propeptide domain-containing protein. (219 aa)
PTH1RUncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (619 aa)
HIF1AUncharacterized protein. (851 aa)
RB1RB transcriptional corepressor 1. (943 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (469 aa)
SOX5SRY-box transcription factor 5. (779 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (584 aa)
CYTL1Uncharacterized protein. (195 aa)
MUSTN1Uncharacterized protein. (82 aa)
ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif 7. (1654 aa)
ENSOCUP00000037873Uncharacterized protein. (411 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1060 aa)
TRIP11Thyroid hormone receptor interactor 11. (1982 aa)
FGF18Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (231 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (852 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (586 aa)
ENSOCUP00000032595Runt domain-containing protein. (357 aa)
COL11A1Collagen type XI alpha 1 chain. (1857 aa)
ENSOCUP00000032400Uncharacterized protein. (531 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
SOX6SRY-box transcription factor 6. (855 aa)
ENSOCUP00000031395Uncharacterized protein; Belongs to the serpin family. (216 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
IMPAD1Inositol monophosphatase domain containing 1. (368 aa)
ENSOCUP00000028861SERPIN domain-containing protein; Belongs to the serpin family. (321 aa)
SHOX2Short stature homeobox 2. (211 aa)
CHSY1Hexosyltransferase. (751 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
SULF2Sulfatase 2. (785 aa)
SIX2SIX homeobox 2. (295 aa)
SERPINH1SERPIN domain-containing protein; Belongs to the serpin family. (201 aa)
OSR2Odd-skipped related transciption factor 2. (312 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (1024 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (397 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (202 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
COL11A2Collagen type XI alpha 2 chain. (1656 aa)
G1TBJ9_RABITUncharacterized protein. (276 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
COL3A1Collagen type III alpha 1 chain. (1462 aa)
IFT80Intraflagellar transport 80. (777 aa)
NPPCUncharacterized protein. (351 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (466 aa)
COL2A1Fibrillar collagen NC1 domain-containing protein. (1487 aa)
MEX3CMex-3 RNA binding family member C. (494 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1033 aa)
MEF2DMyocyte enhancer factor 2D. (517 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (498 aa)
ARID5AAT-rich interaction domain 5A. (555 aa)
ECM1Extracellular matrix protein 1. (563 aa)
RUNX2RUNX family transcription factor 2. (343 aa)
BMP2Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4. (271 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (657 aa)
BMP4Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). (409 aa)
CCN3Cellular communication network factor 3. (357 aa)
GDF5Growth differentiation factor 5 preproprotein (Predicted). (500 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
MATN1Matrilin 1. (724 aa)
GLI3GLI family zinc finger 3. (1575 aa)
ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif 12. (1598 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
ANXA6Annexin. (913 aa)
COL27A1LAM_G_DOMAIN domain-containing protein. (1333 aa)
SULF1Sulfatase 1. (846 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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