STRINGSTRING
TREX1 TREX1 KCP KCP FLT1 FLT1 HOXB3 HOXB3 ORYCUNV1R1524 ORYCUNV1R1524 GATA3 GATA3 SLC37A4 SLC37A4 ZFAT ZFAT BVES BVES SHH SHH PRRC2C PRRC2C LIG4 LIG4 EXT1 EXT1 PSEN1 PSEN1 RRS1 RRS1 PTPRZ1 PTPRZ1 ZBTB24 ZBTB24 ATF2 ATF2 RBM47 RBM47 PTPRC PTPRC PYGO1 PYGO1 SMPD3 SMPD3 FLT4 FLT4 BMP4 BMP4 DACT2 DACT2 ESCO2 ESCO2 TENT2 TENT2 AGPAT5 AGPAT5 SIPA1L3 SIPA1L3 DHTKD1 DHTKD1 SLC7A6OS SLC7A6OS G1SV95_RABIT G1SV95_RABIT MLLT3 MLLT3 XRCC5 XRCC5 HYAL2 HYAL2 KDR KDR FLT3 FLT3 FST FST SP7 SP7 ZFP36 ZFP36 LYN LYN WDR38 WDR38 MEOX1 MEOX1 SRF SRF SH2B3 SH2B3 HEATR9 HEATR9 TOP2A TOP2A WDR7 WDR7 UFL1 UFL1 REST REST MMP21 MMP21 TP53 TP53 INHBA INHBA ACP6 ACP6 PDGFRA PDGFRA SP3 SP3 ADAR ADAR ENSOCUP00000048311 ENSOCUP00000048311 CITED2 CITED2 ENSOCUP00000047273 ENSOCUP00000047273 ENSOCUP00000045944 ENSOCUP00000045944 SLC8A3 SLC8A3 ENSOCUP00000045925 ENSOCUP00000045925 AP3B1 AP3B1 LMBR1L LMBR1L ENSOCUP00000044284 ENSOCUP00000044284 XRCC4 XRCC4 JAM3 JAM3 ENSOCUP00000042043 ENSOCUP00000042043 ENSOCUP00000041840 ENSOCUP00000041840 CDK6 CDK6 ENSOCUP00000039002 ENSOCUP00000039002 SBDS SBDS PLEK PLEK ENSOCUP00000037329 ENSOCUP00000037329 CHD2 CHD2 BCL2 BCL2 KIT KIT CSF1R CSF1R SIN3A SIN3A KITLG KITLG TMEM143 TMEM143 EML1 EML1 LOC103345451 LOC103345451 BRAF BRAF ANLN ANLN ENSOCUP00000029917 ENSOCUP00000029917 ERCC2 ERCC2 MLF1 MLF1 LOC100358984 LOC100358984 HERC6 HERC6 PTPRQ PTPRQ G1U940_RABIT G1U940_RABIT SERPINB12 SERPINB12 ARMC6 ARMC6 NARF NARF SAMD9 SAMD9 WDR78 WDR78 ARL11 ARL11 C12orf29 C12orf29 TNFRSF13B TNFRSF13B MED1 MED1 SAMD9L SAMD9L BATF BATF MIXL1 MIXL1 G1TT13_RABIT G1TT13_RABIT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TREX1Three prime repair exonuclease 1. (314 aa)
KCPKielin cysteine rich BMP regulator. (1203 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1479 aa)
HOXB3Homeobox B3. (434 aa)
ORYCUNV1R1524Vomeronasal type-1 receptor. (311 aa)
GATA3GATA binding protein 3. (444 aa)
SLC37A4Solute carrier family 37 member 4. (451 aa)
ZFATZinc finger and AT-hook domain containing. (1185 aa)
BVESBlood vessel epicardial substance. (361 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (451 aa)
PRRC2CProline rich coiled-coil 2C. (2778 aa)
LIG4DNA ligase. (911 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (557 aa)
RRS1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (345 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2272 aa)
ZBTB24Zinc finger and BTB domain containing 24. (700 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (498 aa)
RBM47RNA binding motif protein 47. (591 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
PYGO1Pygopus family PHD finger 1. (419 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (657 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1390 aa)
BMP4Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). (409 aa)
DACT2Uncharacterized protein. (661 aa)
ESCO2Establishment of sister chromatid cohesion N-acetyltransferase 2. (609 aa)
TENT2Terminal nucleotidyltransferase 2. (484 aa)
AGPAT5Acyltransf_C domain-containing protein. (197 aa)
SIPA1L3Signal induced proliferation associated 1 like 3. (1777 aa)
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (1058 aa)
SLC7A6OSSolute carrier family 7 member 6 opposite strand. (309 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
MLLT3MLLT3 super elongation complex subunit. (572 aa)
XRCC5X-ray repair cross complementing 5. (733 aa)
HYAL2Hyaluronidase. (475 aa)
KDRUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
FSTFollistatin. (310 aa)
SP7Sp7 transcription factor. (431 aa)
ZFP36ZFP36 ring finger protein. (338 aa)
LYNTyrosine-protein kinase. (636 aa)
WDR38WD repeat domain 38. (315 aa)
MEOX1Mesenchyme homeobox 1. (254 aa)
SRFSerum response factor. (685 aa)
SH2B3SH2B adaptor protein 3. (354 aa)
HEATR9HEAT repeat containing 9. (565 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1513 aa)
WDR7WD repeat domain 7. (1494 aa)
UFL1UFM1 specific ligase 1. (793 aa)
RESTRE1 silencing transcription factor. (930 aa)
MMP21Matrix metallopeptidase 21; Belongs to the peptidase M10A family. (567 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (391 aa)
INHBAInhibin subunit beta A. (424 aa)
ACP6Acid phosphatase 6, lysophosphatidic; Belongs to the histidine acid phosphatase family. (430 aa)
PDGFRAProtein kinase domain-containing protein. (773 aa)
SP3Sp3 transcription factor. (715 aa)
ADARAdenosine deaminase RNA specific. (1182 aa)
ENSOCUP00000048311Uncharacterized protein. (121 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (249 aa)
ENSOCUP00000047273Uncharacterized protein. (231 aa)
ENSOCUP00000045944Helicase C-terminal domain-containing protein. (368 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (958 aa)
ENSOCUP00000045925TGFb_propeptide domain-containing protein. (272 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1187 aa)
LMBR1LLimb development membrane protein 1 like; Belongs to the LIMR family. (518 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
XRCC4X-ray repair cross complementing 4. (348 aa)
JAM3Junctional adhesion molecule 3. (405 aa)
ENSOCUP00000042043Ig-like domain-containing protein. (212 aa)
ENSOCUP00000041840TGFb_propeptide domain-containing protein. (219 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (349 aa)
ENSOCUP00000039002Uncharacterized protein. (163 aa)
SBDSSBDS ribosome maturation factor. (263 aa)
PLEKPleckstrin. (350 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
CHD2DUF4208 domain-containing protein. (551 aa)
BCL2BH4_2 domain-containing protein. (389 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (973 aa)
SIN3ASIN3 transcription regulator family member A. (1241 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (276 aa)
TMEM143Transmembrane protein 143. (506 aa)
EML1EMAP like 1. (785 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (767 aa)
ANLNAnillin actin binding protein. (1170 aa)
ENSOCUP00000029917Uncharacterized protein. (169 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (805 aa)
MLF1Myeloid leukemia factor 1. (286 aa)
LOC100358984Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (857 aa)
HERC6HECT and RLD domain containing E3 ubiquitin protein ligase family member 6. (998 aa)
PTPRQProtein tyrosine phosphatase receptor type Q. (2300 aa)
G1U940_RABITCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (178 aa)
SERPINB12SERPIN domain-containing protein; Belongs to the serpin family. (424 aa)
ARMC6Armadillo repeat containing 6. (397 aa)
NARFNuclear prelamin A recognition factor; Belongs to the NARF family. (409 aa)
SAMD9Sterile alpha motif domain containing 9. (1333 aa)
WDR78WD repeat domain 78. (810 aa)
ARL11ADP ribosylation factor like GTPase 11; Belongs to the small GTPase superfamily. Arf family. (182 aa)
C12orf29Chromosome 12 open reading frame 29. (446 aa)
TNFRSF13BTNF receptor superfamily member 13B. (276 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1580 aa)
SAMD9LSterile alpha motif domain containing 9 like. (1584 aa)
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)
MIXL1Mix paired-like homeobox. (234 aa)
G1TT13_RABITBZIP domain-containing protein. (136 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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