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PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (557 aa) | ||||
IL20 | Interleukin 20. (187 aa) | ||||
BATF2 | Basic leucine zipper ATF-like transcription factor 2. (274 aa) | ||||
DHRS7B | Dehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (325 aa) | ||||
GPR68 | G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (375 aa) | ||||
TCTA | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. (106 aa) | ||||
BMP4 | Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). (409 aa) | ||||
EIF2AK1 | Eukaryotic translation initiation factor 2-alpha kinase 1; Inhibits protein synthesis at the translation initiation level, in response to various stress conditions, including oxidative stress, heme deficiency, osmotic shock and heat shock. Exerts its function through the phosphorylation of EIF2S1 at 'Ser-48' and 'Ser- 51', thus preventing its recycling. Binds hemin forming a 1:1 complex through a cysteine thiolate and histidine nitrogenous coordination. This binding occurs with moderate affinity, allowing it to sense the heme concentration within the cell. Thanks to this unique heme-se [...] (618 aa) | ||||
LBR | Lamin B receptor. (627 aa) | ||||
TSPAN2 | Tetraspanin. (220 aa) | ||||
LTBR | Lymphotoxin beta receptor. (414 aa) | ||||
GPC3 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa) | ||||
MITF | Melanocyte inducing transcription factor. (526 aa) | ||||
F2RL1 | F2R like trypsin receptor 1. (397 aa) | ||||
CSF2 | Uncharacterized protein. (144 aa) | ||||
MYH9 | Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1920 aa) | ||||
DCSTAMP | DC_STAMP domain-containing protein. (283 aa) | ||||
SNX10 | Sorting nexin 10. (117 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) | ||||
TNFRSF11A | TNFR-Cys domain-containing protein. (349 aa) | ||||
LOC100348108 | AIG1-type G domain-containing protein. (312 aa) | ||||
CD109 | CD109 molecule. (1318 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) | ||||
G1SSE7_RABIT | Uncharacterized protein; Belongs to the peptidase C14A family. (306 aa) | ||||
FOXP1 | Fork-head domain-containing protein. (714 aa) | ||||
IL31RA | Interleukin 31 receptor A. (730 aa) | ||||
SRP54 | Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (499 aa) | ||||
G1SV95_RABIT | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) | ||||
NF1 | Neurofibromin 1. (2841 aa) | ||||
LRRK1 | Leucine rich repeat kinase 1. (2013 aa) | ||||
IL15 | Interleukin-15; Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (By similarity). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, which results in kinase SYK activation (By similarity). (162 aa) | ||||
FARP2 | FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1013 aa) | ||||
IRF4 | Interferon regulatory factor 4. (451 aa) | ||||
CSF3 | Colony stimulating factor 3. (204 aa) | ||||
IREB2 | Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. (956 aa) | ||||
APP | Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (769 aa) | ||||
G1T067_RABIT | Fam20C domain-containing protein. (543 aa) | ||||
ENSOCUP00000041840 | TGFb_propeptide domain-containing protein. (219 aa) | ||||
GLO1 | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (206 aa) | ||||
ENSOCUP00000044284 | TGFb_propeptide domain-containing protein. (260 aa) | ||||
AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1187 aa) | ||||
ENSOCUP00000045925 | TGFb_propeptide domain-containing protein. (272 aa) | ||||
ENSOCUP00000046340 | RHD domain-containing protein. (343 aa) | ||||
CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (249 aa) | ||||
L3MBTL3 | L3MBTL histone methyl-lysine binding protein 3. (780 aa) | ||||
SP3 | Sp3 transcription factor. (715 aa) | ||||
ENSOCUP00000049280 | SCY domain-containing protein. (136 aa) | ||||
LEF1 | Lymphoid enhancer binding factor 1. (414 aa) | ||||
BAP1 | BRCA1 associated protein 1. (731 aa) | ||||
LOC100348748 | IGv domain-containing protein. (604 aa) | ||||
JUN | BZIP domain-containing protein; Belongs to the bZIP family. (352 aa) | ||||
SH3PXD2A | SH3 and PX domains 2A. (1119 aa) | ||||
CCL19 | C-C motif chemokine. (109 aa) | ||||
ENSOCUP00000037329 | TGFb_propeptide domain-containing protein. (263 aa) | ||||
ENSOCUP00000037059 | Uncharacterized protein. (317 aa) | ||||
NOTCH2 | Notch receptor 2. (2481 aa) | ||||
KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa) | ||||
CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (973 aa) | ||||
ENSOCUP00000034457 | VOC domain-containing protein. (185 aa) | ||||
KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (276 aa) | ||||
PDE1B | Phosphodiesterase. (563 aa) | ||||
CTNNB1 | Catenin beta 1. (741 aa) | ||||
LOC103345451 | TGFb_propeptide domain-containing protein. (203 aa) | ||||
THOC5 | THO complex 5. (748 aa) | ||||
TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) | ||||
IL25 | Interleukin 25. (177 aa) | ||||
GAB3 | PH domain-containing protein. (724 aa) | ||||
ENSOCUP00000029917 | Uncharacterized protein. (169 aa) | ||||
ITGB6 | Integrin beta; Belongs to the integrin beta chain family. (787 aa) | ||||
ENSOCUP00000027264 | Protein kinase domain-containing protein. (77 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (552 aa) | ||||
CSF1 | Colony stimulating factor 1. (535 aa) | ||||
UBD | Ubiquitin D. (182 aa) | ||||
GATA1 | GATA binding protein 1. (413 aa) | ||||
IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (144 aa) | ||||
SIRT1 | Sirtuin 1. (748 aa) | ||||
P2RY8 | P2Y receptor family member 8; Belongs to the G-protein coupled receptor 1 family. (382 aa) | ||||
OSCAR | Ig-like domain-containing protein. (323 aa) | ||||
CEBPA | CCAAT enhancer binding protein alpha. (402 aa) | ||||
G1TXH1_RABIT | BTB domain-containing protein. (421 aa) | ||||
FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) | ||||
MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1580 aa) | ||||
GPR183 | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (327 aa) | ||||
BATF | Basic leucine zipper ATF-like transcription factor. (125 aa) | ||||
CALCR | Calcitonin receptor; This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. Isoform 2 has altered ligand binding and abolished coupling to phospholipase C. (491 aa) | ||||
CASP10 | Caspase-10; Belongs to the peptidase C14A family. (469 aa) | ||||
NRROS | Negative regulator of reactive oxygen species. (692 aa) | ||||
CAMK4 | Protein kinase domain-containing protein. (264 aa) | ||||
CEBPE | CCAAT/enhancer-binding protein. (281 aa) | ||||
G1TLQ5_RABIT | Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family. (245 aa) | ||||
SPIB | ETS domain-containing protein. (158 aa) | ||||
CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa) | ||||
EPHA2 | EPH receptor A2. (1031 aa) | ||||
G1TH84_RABIT | AIG1-type G domain-containing protein. (194 aa) | ||||
OCSTAMP | Osteoclast stimulatory transmembrane protein. (481 aa) | ||||
GAB2 | GRB2 associated binding protein 2. (679 aa) | ||||
TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa) | ||||
GATA3 | GATA binding protein 3. (444 aa) | ||||
PIR | Pirin; Belongs to the pirin family. (473 aa) | ||||
ATP6AP1 | Uncharacterized protein. (470 aa) | ||||
TFRC | Transferrin receptor. (763 aa) | ||||
CCN4 | Cellular communication network factor 4. (337 aa) | ||||
OSTM1 | Uncharacterized protein. (331 aa) |