24 items (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMP4	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). (409 aa)
	GATA4	GATA binding protein 4. (444 aa)
	ROBO1	Roundabout guidance receptor 1. (1651 aa)
	ROBO2	Roundabout guidance receptor 2. (1438 aa)
	EFNA1	Ephrin A1; Belongs to the ephrin family. (205 aa)
	SMAD6	MH2 domain-containing protein. (220 aa)
	NFATC1	RHD domain-containing protein. (672 aa)
	EMILIN1	Elastin microfibril interfacer 1. (982 aa)
	G1SV95_RABIT	Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
	TIE1	Tyrosine kinase with immunoglobulin like and EGF like domains 1. (732 aa)
	HEY1	Hes related family bHLH transcription factor with YRPW motif 1. (452 aa)
	GATA3	GATA binding protein 3. (444 aa)
	NOS3	Nitric oxide synthase; Produces nitric oxide (NO). (1209 aa)
	HEY2	Hes related family bHLH transcription factor with YRPW motif 2. (338 aa)
	SLIT2	Slit guidance ligand 2. (1542 aa)
	TBX20	T-box transcription factor 20. (460 aa)
	LOC103345451	TGFb_propeptide domain-containing protein. (203 aa)
	ENSOCUP00000035160	Ig domain-containing protein. (246 aa)
	ENSOCUP00000037329	TGFb_propeptide domain-containing protein. (263 aa)
	RB1	RB transcriptional corepressor 1. (943 aa)
	ENSOCUP00000041840	TGFb_propeptide domain-containing protein. (219 aa)
	ENSOCUP00000044284	TGFb_propeptide domain-containing protein. (260 aa)
	ENSOCUP00000045925	TGFb_propeptide domain-containing protein. (272 aa)
	SLIT3	Slit guidance ligand 3. (1530 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	ENSOCUP00000037329	ENSOCUP00000009545	ENSOCUP00000037329	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	TGFb_propeptide domain-containing protein.	0.612
BMP4	ENSOCUP00000044284	ENSOCUP00000009545	ENSOCUP00000044284	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	TGFb_propeptide domain-containing protein.	0.612
BMP4	GATA3	ENSOCUP00000009545	ENSOCUP00000015302	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	GATA binding protein 3.	0.505
BMP4	GATA4	ENSOCUP00000009545	ENSOCUP00000001897	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	GATA binding protein 4.	0.846
BMP4	HEY1	ENSOCUP00000009545	ENSOCUP00000014239	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	Hes related family bHLH transcription factor with YRPW motif 1.	0.544
BMP4	HEY2	ENSOCUP00000009545	ENSOCUP00000027193	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	Hes related family bHLH transcription factor with YRPW motif 2.	0.423
BMP4	LOC103345451	ENSOCUP00000009545	ENSOCUP00000031740	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	TGFb_propeptide domain-containing protein.	0.612
BMP4	SMAD6	ENSOCUP00000009545	ENSOCUP00000005315	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	MH2 domain-containing protein.	0.861
BMP4	TBX20	ENSOCUP00000009545	ENSOCUP00000030383	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	T-box transcription factor 20.	0.468
ENSOCUP00000035160	NOS3	ENSOCUP00000035160	ENSOCUP00000025713	Ig domain-containing protein.	Nitric oxide synthase; Produces nitric oxide (NO).	0.574
ENSOCUP00000035160	TIE1	ENSOCUP00000035160	ENSOCUP00000007755	Ig domain-containing protein.	Tyrosine kinase with immunoglobulin like and EGF like domains 1.	0.924
ENSOCUP00000037329	BMP4	ENSOCUP00000037329	ENSOCUP00000009545	TGFb_propeptide domain-containing protein.	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	0.612
ENSOCUP00000037329	ENSOCUP00000044284	ENSOCUP00000037329	ENSOCUP00000044284	TGFb_propeptide domain-containing protein.	TGFb_propeptide domain-containing protein.	0.412
ENSOCUP00000037329	LOC103345451	ENSOCUP00000037329	ENSOCUP00000031740	TGFb_propeptide domain-containing protein.	TGFb_propeptide domain-containing protein.	0.419
ENSOCUP00000037329	SMAD6	ENSOCUP00000037329	ENSOCUP00000005315	TGFb_propeptide domain-containing protein.	MH2 domain-containing protein.	0.548
ENSOCUP00000041840	SMAD6	ENSOCUP00000041840	ENSOCUP00000005315	TGFb_propeptide domain-containing protein.	MH2 domain-containing protein.	0.449
ENSOCUP00000044284	BMP4	ENSOCUP00000044284	ENSOCUP00000009545	TGFb_propeptide domain-containing protein.	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	0.612
ENSOCUP00000044284	ENSOCUP00000037329	ENSOCUP00000044284	ENSOCUP00000037329	TGFb_propeptide domain-containing protein.	TGFb_propeptide domain-containing protein.	0.412
ENSOCUP00000044284	SMAD6	ENSOCUP00000044284	ENSOCUP00000005315	TGFb_propeptide domain-containing protein.	MH2 domain-containing protein.	0.548
ENSOCUP00000045925	SMAD6	ENSOCUP00000045925	ENSOCUP00000005315	TGFb_propeptide domain-containing protein.	MH2 domain-containing protein.	0.449