STRINGSTRING
MYO1B MYO1B IQGAP1 IQGAP1 FBXL20 FBXL20 MYO1G MYO1G IQCF5 IQCF5 NOS3 NOS3 RYR1 RYR1 MYO1F MYO1F MYO10 MYO10 LOC100338257 LOC100338257 MYH11 MYH11 PHKA1 PHKA1 MYH13 MYH13 STRN4 STRN4 CACNA1S CACNA1S MYO6 MYO6 SLC9A1 SLC9A1 MYLK MYLK MYO5B MYO5B AKAP5 AKAP5 CAMSAP3 CAMSAP3 SMTNL1 SMTNL1 MYH7 MYH7 ADD1 ADD1 PPP3CB PPP3CB CAMK4 CAMK4 G1TP34_RABIT G1TP34_RABIT MYO7A MYO7A ITPKA ITPKA MYH1 MYH1 MIP MIP IQGAP2 IQGAP2 ORAI1 ORAI1 CAMK1 CAMK1 SNTB2 SNTB2 SYT7 SYT7 ATP5IF1 ATP5IF1 CAMK2A CAMK2A MYO3A MYO3A ZNF365 ZNF365 G1U9S3_RABIT G1U9S3_RABIT PDE1A PDE1A SNTB1 SNTB1 MYO1E MYO1E SLC24A4 SLC24A4 ADCY3 ADCY3 AEBP1 AEBP1 KCNN2 KCNN2 MYO9B MYO9B ASPM ASPM SPATA17 SPATA17 ADD2 ADD2 PHKG2 PHKG2 PHKG1 PHKG1 SPTAN1 SPTAN1 TRPV1 TRPV1 KCNQ3 KCNQ3 MAP6D1 MAP6D1 STRN3 STRN3 MYH8 MYH8 VAMP2 VAMP2 CFAP221 CFAP221 CNGA2 CNGA2 IQCB1 IQCB1 MARCKSL1 MARCKSL1 KCNH5 KCNH5 CAMKV CAMKV LOC100342707 LOC100342707 ATP2B3 ATP2B3 ARPP21 ARPP21 ENSOCUP00000049447 ENSOCUP00000049447 CAMK2G CAMK2G ENKUR ENKUR ATP2B1 ATP2B1 UNC13B UNC13B CASK CASK DAPK1 DAPK1 ENSOCUP00000046835 ENSOCUP00000046835 SLC8A3 SLC8A3 LOC100356734 LOC100356734 MYO1C MYO1C PPP3CA PPP3CA RYR3 RYR3 FBXL2 FBXL2 LOC100357816 LOC100357816 CAMK1G CAMK1G MKNK1 MKNK1 PHKA2 PHKA2 LOC100344065 LOC100344065 ENSOCUP00000041637 ENSOCUP00000041637 AKAP12 AKAP12 CALD1 CALD1 MYLK2 MYLK2 KCNQ1 KCNQ1 CEP97 CEP97 ENSOCUP00000039758 ENSOCUP00000039758 PDE1C PDE1C CACNA1C CACNA1C GAP43 GAP43 MYH10 MYH10 CAMK1D CAMK1D PHKB PHKB PCYT1A PCYT1A UBR4 UBR4 KCNH1 KCNH1 LOC100339409 LOC100339409 IQCG IQCG MYO1A MYO1A NOS2 NOS2 NDUFAF4 NDUFAF4 RYR2 RYR2 NRGN NRGN CAMKK2 CAMKK2 RIT1 RIT1 ATP2B4 ATP2B4 EPB41 EPB41 MARCKS MARCKS STRN STRN ADCY8 ADCY8 REM1 REM1 G1SJF5_RABIT G1SJF5_RABIT IQGAP3 IQGAP3 MYH4 MYH4 LOC100008687 LOC100008687 RIT2 RIT2 MYH9 MYH9 INVS INVS TRPV4 TRPV4 PCNT PCNT MAPKAPK3 MAPKAPK3 G1SP45_RABIT G1SP45_RABIT PLA2G6 PLA2G6 KCNN4 KCNN4 CTH CTH TRPV6 TRPV6 TRPV5 TRPV5 NGFR NGFR MYO5A MYO5A LOC100345702 LOC100345702 CAMSAP2 CAMSAP2 ITPKC ITPKC SCN5A SCN5A EEF2K EEF2K MYO1D MYO1D MAP2 MAP2 UNC13C UNC13C ENSOCUP00000031759 ENSOCUP00000031759 ENSOCUP00000032183 ENSOCUP00000032183 CAMK2D CAMK2D MAPKAPK5 MAPKAPK5 ALG14 ALG14 KCNQ5 KCNQ5 PDE1B PDE1B SLC8A1 SLC8A1 FAS FAS ENSOCUP00000034231 ENSOCUP00000034231 PNCK PNCK ITPKB ITPKB PLCB1 PLCB1 CAMKK1 CAMKK1 PCP4 PCP4 SPHK1 SPHK1 ENSOCUP00000029750 ENSOCUP00000029750 KCNN3 KCNN3 RRAD RRAD PPP3CC PPP3CC SNTA1 SNTA1 ENSOCUP00000027264 ENSOCUP00000027264 U3KNR5_RABIT U3KNR5_RABIT IQCF3 IQCF3 ADD3 ADD3 IQCF6 IQCF6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYO1BMyosin IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1128 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1727 aa)
FBXL20F-box and leucine rich repeat protein 20. (438 aa)
MYO1GUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (509 aa)
IQCF5IQ motif containing F5. (150 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1209 aa)
RYR1Ryanodine receptor 1; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high- level exercise increases the open probability of the channel and leads to Ca(2+) leaking into the cytoplasm (By similarity). Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. [...] (4598 aa)
MYO1FMyosin IF; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1098 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2067 aa)
LOC100338257Uncharacterized protein. (1064 aa)
MYH11Myosin-11; Muscle contraction. (1944 aa)
PHKA1Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin. (1237 aa)
MYH13Skeletal muscle myosin heavy chain MyHC-EO/IIL; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
STRN4Striatin 4. (598 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha-1S; Pore-forming, alpha-1S subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle via their interaction with RYR1, which triggers Ca(2+) release from the sarcplasmic reticulum and ultimately results in muscle contraction. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. (1828 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1285 aa)
SLC9A1Sodium/hydrogen exchanger 1; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
MYLKMyosin light chain kinase, smooth muscle, deglutamylated form; Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscle contraction that is necessa [...] (1063 aa)
MYO5BUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1848 aa)
AKAP5A-kinase anchoring protein 5. (403 aa)
CAMSAP3Calmodulin regulated spectrin associated protein family member 3. (1071 aa)
SMTNL1Smoothelin like 1. (459 aa)
MYH7Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
ADD1Adducin 1. (622 aa)
PPP3CBSerine/threonine-protein phosphatase. (518 aa)
CAMK4Protein kinase domain-containing protein. (264 aa)
G1TP34_RABITProtein kinase domain-containing protein. (360 aa)
MYO7AMyosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2148 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (443 aa)
MYH1Myosin-4; Muscle contraction. (1938 aa)
MIPLens fiber major intrinsic protein; Water channel. Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core. Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (By similarity). Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1538 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (302 aa)
CAMK1Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (371 aa)
SNTB2Syntrophin beta 2. (515 aa)
SYT7Synaptotagmin 7. (523 aa)
ATP5IF1Uncharacterized protein. (148 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (469 aa)
MYO3AMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1582 aa)
ZNF365Zinc finger protein 365. (407 aa)
G1U9S3_RABITUncharacterized protein. (438 aa)
PDE1APhosphodiesterase. (593 aa)
SNTB1Syntrophin beta 1. (540 aa)
MYO1EMyosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1107 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (613 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1138 aa)
AEBP1AE binding protein 1. (1134 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (556 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1613 aa)
ASPMUncharacterized protein. (1883 aa)
SPATA17Spermatogenesis associated 17. (362 aa)
ADD2Adducin 2. (724 aa)
PHKG2Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily. (406 aa)
PHKG1Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (387 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2541 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Can be activated by endogenous compounds, including 12-hydroperoxytetraenoic acid and bradykinin. Ac [...] (842 aa)
KCNQ3Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (809 aa)
MAP6D1MAP6 domain containing 1. (193 aa)
STRN3Striatin 3. (713 aa)
MYH8Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (226 aa)
CFAP221Cilia and flagella associated protein 221. (839 aa)
CNGA2Cyclic nucleotide-gated olfactory channel; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons; Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA2 subfamily. (696 aa)
IQCB1IQ motif containing B1. (598 aa)
MARCKSL1MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable). (189 aa)
KCNH5Potassium voltage-gated channel subfamily H member 5. (988 aa)
CAMKVCaM kinase like vesicle associated. (498 aa)
LOC100342707Uncharacterized protein. (191 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1245 aa)
ARPP21cAMP regulated phosphoprotein 21. (845 aa)
ENSOCUP00000049447Uncharacterized protein. (168 aa)
CAMK2GProtein kinase domain-containing protein. (592 aa)
ENKUREnkurin, TRPC channel interacting protein. (262 aa)
ATP2B1Plasma membrane calcium-transporting ATPase 1; Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-ind [...] (1249 aa)
UNC13BUncharacterized protein. (4294 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (1000 aa)
DAPK1Death associated protein kinase 1. (1493 aa)
ENSOCUP00000046835Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (564 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (958 aa)
LOC100356734Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1283 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1000 aa)
PPP3CASerine/threonine-protein phosphatase. (695 aa)
RYR3Ryanodine receptor 3; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction. May regulate Ca(2+) release by other calcium channels. Calcium channel that mediates Ca(2+)-induced Ca(2+) release from the endoplasmic reticulum in non-muscle cells. Plays a role in cellular calcium signaling. Contributes to cellular calcium ion homeostasis. Isoform 2 lacks a predicted transmembrane segment and does not form functional calcium channels by itself; however, it can form tetramers [...] (4876 aa)
FBXL2F-box and leucine rich repeat protein 2. (379 aa)
LOC100357816Uncharacterized protein. (198 aa)
CAMK1GCalcium/calmodulin dependent protein kinase IG. (574 aa)
MKNK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (427 aa)
PHKA2Phosphorylase b kinase regulatory subunit alpha, liver isoform; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin. (1255 aa)
LOC100344065Uncharacterized protein. (161 aa)
ENSOCUP00000041637Uncharacterized protein. (83 aa)
AKAP12A-kinase anchoring protein 12. (1740 aa)
CALD1Uncharacterized protein. (557 aa)
MYLK2Myosin light chain kinase 2, skeletal/cardiac muscle; Implicated in the level of global muscle contraction and cardiac function (By similarity). Phosphorylates a specific serine in the N-terminus of a myosin light chain. (608 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] (695 aa)
CEP97Centrosomal protein 97. (860 aa)
ENSOCUP00000039758Myosin_tail_1 domain-containing protein. (230 aa)
PDE1CPhosphodiesterase. (767 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha-1C; Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm. Plays an important role in excitation-contraction coupling in the heart. Required for normal heart development and normal regulation of heart rhythm (By similarity). Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. Essential for normal blood pressure regulation via [...] (2141 aa)
GAP43Uncharacterized protein. (410 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
CAMK1DCalcium/calmodulin dependent protein kinase ID. (355 aa)
PHKBPhosphorylase b kinase regulatory subunit beta; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation. (1121 aa)
PCYT1APhosphate cytidylyltransferase 1, choline, alpha. (381 aa)
UBR4Ubiquitin protein ligase E3 component n-recognin 4. (5180 aa)
KCNH1Uncharacterized protein. (989 aa)
LOC100339409Uncharacterized protein. (106 aa)
IQCGIQ motif containing G. (429 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
NOS2Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1146 aa)
NDUFAF4Uncharacterized protein. (175 aa)
RYR2Ryanodine receptor 2; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. Required for cellular calcium ion homeostasis. Required for embryonic heart development (By similarity). The calcium channel activity is modulated by formation of heterotetramers with RYR3; Belongs to t [...] (4965 aa)
NRGNNeurogranin. (78 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (693 aa)
RIT1Ras like without CAAX 1. (220 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
EPB41Erythrocyte membrane protein band 4.1. (860 aa)
MARCKSMyristoylated alanine rich protein kinase C substrate. (333 aa)
STRNStriatin. (702 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
G1SJF5_RABITUncharacterized protein. (530 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1720 aa)
MYH4Myosin-4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
LOC100008687Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa)
RIT2Ras-like GTP binding protein. (217 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1920 aa)
INVSInversin. (1115 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (679 aa)
PCNTPericentrin. (3295 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
G1SP45_RABITCalponin-homology (CH) domain-containing protein. (243 aa)
PLA2G6Uncharacterized protein. (485 aa)
KCNN4Potassium calcium-activated channel subfamily N member 4. (404 aa)
CTHCystathionine gamma-lyase. (411 aa)
TRPV6ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (699 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules (By similarity). The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric con [...] (730 aa)
NGFRNerve growth factor receptor. (407 aa)
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2013 aa)
LOC100345702Uncharacterized protein. (1089 aa)
CAMSAP2Calmodulin regulated spectrin associated protein family member 2. (1495 aa)
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (636 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1847 aa)
EEF2KEukaryotic elongation factor 2 kinase. (725 aa)
MYO1DMyosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1021 aa)
MAP2Microtubule-associated protein. (1921 aa)
UNC13CUnc-13 homolog C. (2216 aa)
ENSOCUP00000031759Guanylate cyclase domain-containing protein. (312 aa)
ENSOCUP00000032183Uncharacterized protein. (349 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta; Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca(2+) influx into the myocyte, Ca(2+) release from the sarcoplasmic reticulum (SR), SR Ca(2+) uptake and Na(+) and K(+) channel transport. Targets also transcription factors and signaling molecules to regulate heart function. In its activated form, is involved in the pathogenesis of dilated cardiomyopath [...] (505 aa)
MAPKAPK5MAPK activated protein kinase 5. (537 aa)
ALG14Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (526 aa)
KCNQ5Potassium voltage-gated channel subfamily Q member 5. (951 aa)
PDE1BPhosphodiesterase. (563 aa)
SLC8A1J domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
FASUncharacterized protein. (484 aa)
ENSOCUP00000034231Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (213 aa)
PNCKPregnancy up-regulated nonubiquitous CaM kinase. (439 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (924 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1215 aa)
CAMKK1Calcium/calmodulin dependent protein kinase kinase 1. (720 aa)
PCP4Purkinje cell protein 4. (71 aa)
SPHK1Sphingosine kinase 1. (455 aa)
ENSOCUP00000029750Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (907 aa)
KCNN3Potassium calcium-activated channel subfamily N member 3. (740 aa)
RRADRRAD, Ras related glycolysis inhibitor and calcium channel regulator. (349 aa)
PPP3CCSerine/threonine-protein phosphatase. (574 aa)
SNTA1Alpha-1-syntrophin; Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate (By similarity). (548 aa)
ENSOCUP00000027264Protein kinase domain-containing protein. (77 aa)
U3KNR5_RABITUncharacterized protein. (193 aa)
IQCF3Uncharacterized protein. (154 aa)
ADD3Adducin 3. (705 aa)
IQCF6IQ motif containing F6. (127 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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