STRINGSTRING
GAREM1 GAREM1 PLCE1 PLCE1 PDPK1 PDPK1 GAB1 GAB1 SLC30A10 SLC30A10 FAM83B FAM83B PTPN11 PTPN11 CAMLG CAMLG G1SV95_RABIT G1SV95_RABIT ABL2 ABL2 ADAM17 ADAM17 EGFR EGFR ERBB2 ERBB2 PIGR PIGR EFEMP1 EFEMP1 FAM83A FAM83A SHC1 SHC1 EREG EREG AREG AREG EGF EGF RASSF2 RASSF2 GAREM2 GAREM2 PTK2B PTK2B VIL1 VIL1 SOS1 SOS1 PLCG1 PLCG1 IQGAP1 IQGAP1 PTK2 PTK2 EPGN EPGN BRAF BRAF LOC103345451 LOC103345451 ERBB4 ERBB4 ENSOCUP00000037329 ENSOCUP00000037329 BCAR1 BCAR1 PTK2-2 PTK2-2 ABL1 ABL1 BTC BTC ENSOCUP00000041840 ENSOCUP00000041840 GRB2 GRB2 ENSOCUP00000044284 ENSOCUP00000044284 ENSOCUP00000045925 ENSOCUP00000045925 KIF16B KIF16B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GAREM1GRB2 associated regulator of MAPK1 subtype 1. (923 aa)
PLCE1Phosphoinositide phospholipase C. (2300 aa)
PDPK13-phosphoinositide dependent protein kinase 1; Belongs to the protein kinase superfamily. (325 aa)
GAB1GRB2 associated binding protein 1. (750 aa)
SLC30A10Solute carrier family 30 member 10. (479 aa)
FAM83BFamily with sequence similarity 83 member B. (993 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (292 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
ABL2Tyrosine-protein kinase. (1146 aa)
ADAM17ADAM metallopeptidase domain 17. (827 aa)
EGFRReceptor protein-tyrosine kinase. (1193 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
PIGRPolymeric immunoglobulin receptor; This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. (774 aa)
EFEMP1EGF containing fibulin extracellular matrix protein 1. (494 aa)
FAM83AFamily with sequence similarity 83 member A. (430 aa)
SHC1SHC adaptor protein 1. (474 aa)
EREGEpiregulin. (169 aa)
AREGAmphiregulin. (275 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1198 aa)
RASSF2Ras association domain family member 2. (325 aa)
GAREM2GRB2 associated regulator of MAPK1 subtype 2. (648 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (996 aa)
VIL1Villin 1. (813 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1304 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1727 aa)
PTK2Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1041 aa)
EPGNEpithelial mitogen. (188 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (767 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (869 aa)
PTK2-2FERM_N_2 domain-containing protein. (121 aa)
ABL1Tyrosine-protein kinase. (1118 aa)
BTCBetacellulin. (212 aa)
ENSOCUP00000041840TGFb_propeptide domain-containing protein. (219 aa)
GRB2Growth factor receptor bound protein 2. (278 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
ENSOCUP00000045925TGFb_propeptide domain-containing protein. (272 aa)
KIF16BKinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1860 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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