STRINGSTRING
TXN2 TXN2 KAT5 KAT5 RAB11FIP5 RAB11FIP5 KHK KHK ENSOCUP00000040784 ENSOCUP00000040784 HIF1A HIF1A ENSOCUP00000041421 ENSOCUP00000041421 ENSOCUP00000041840 ENSOCUP00000041840 NOX4 NOX4 ENSOCUP00000043221 ENSOCUP00000043221 TXNIP TXNIP SERPINF1 SERPINF1 LOC100357100 LOC100357100 COL6A2 COL6A2 PRKAA1 PRKAA1 GATA4 GATA4 ADCY8 ADCY8 TWNK TWNK PCK2 PCK2 SRF SRF RACK1 RACK1 SLC29A1 SLC29A1 THBS1 THBS1 SMAD4 SMAD4 GIP GIP EIF2B5 EIF2B5 RBM4 RBM4 PRKAA2 PRKAA2 SLC12A6 SLC12A6 NR0B2 NR0B2 HNF4A HNF4A TJP1 TJP1 ZNF236 ZNF236 PDK3 PDK3 ENSOCUP00000045925 ENSOCUP00000045925 PPP3CA PPP3CA GCLC GCLC ENSOCUP00000044284 ENSOCUP00000044284 XBP1 XBP1 CCDC186 CCDC186 GPAM GPAM EGR1 EGR1 G1SV95_RABIT G1SV95_RABIT SLC30A8 SLC30A8 GYS2 GYS2 AQP4 AQP4 GLUL GLUL ACVR1C ACVR1C VAMP2 VAMP2 FKBP1B FKBP1B SMAD2 SMAD2 GIPR GIPR PCSK1 PCSK1 CYP7A1 CYP7A1 UCP2 UCP2 PAX2 PAX2 NPTX1 NPTX1 CLTRN CLTRN UCN3 UCN3 GCLM GCLM CDKN1B CDKN1B PFKFB2 PFKFB2 IGF1R IGF1R SESN2 SESN2 PKLR PKLR G1T8W0_RABIT G1T8W0_RABIT ANGPT2 ANGPT2 SLC37A4 SLC37A4 PCK1 PCK1 CPB2 CPB2 G1TI49_RABIT G1TI49_RABIT GPER1 GPER1 AGER AGER KCNB1 KCNB1 RAB11FIP2 RAB11FIP2 GJB6 GJB6 SELENOS SELENOS PTK2B PTK2B PRLH PRLH RMI1 RMI1 SIDT2 SIDT2 SARM1 SARM1 ADIPOQ ADIPOQ ENSOCUP00000023367 ENSOCUP00000023367 PTPRN PTPRN PIK3CA PIK3CA ZBTB20 ZBTB20 ICAM1 ICAM1 SELENOT SELENOT PPARD PPARD TRA2B TRA2B TGFBR2 TGFBR2 LOC103345451 LOC103345451 GRIK5 GRIK5 GCK GCK SLC8A1 SLC8A1 GPLD1 GPLD1 SIN3A SIN3A TCF7L2 TCF7L2 LOC100357982 LOC100357982 ENSOCUP00000037329 ENSOCUP00000037329
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TXN2Thioredoxin 2. (166 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (620 aa)
RAB11FIP5Uncharacterized protein. (1311 aa)
KHKKetohexokinase. (352 aa)
ENSOCUP00000040784Uncharacterized protein. (227 aa)
HIF1AUncharacterized protein. (851 aa)
ENSOCUP00000041421CCHC-type domain-containing protein. (189 aa)
ENSOCUP00000041840TGFb_propeptide domain-containing protein. (219 aa)
NOX4NADPH oxidase 4. (638 aa)
ENSOCUP00000043221Uncharacterized protein. (556 aa)
TXNIPThioredoxin interacting protein. (429 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
LOC100357100CCHC-type domain-containing protein. (209 aa)
COL6A2Uncharacterized protein. (425 aa)
PRKAA1Non-specific serine/threonine protein kinase. (656 aa)
GATA4GATA binding protein 4. (444 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
TWNKTwinkle mtDNA helicase. (684 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
SRFSerum response factor. (685 aa)
RACK1WD_REPEATS_REGION domain-containing protein. (424 aa)
SLC29A1Solute carrier family 29 member 1 (Augustine blood group). (456 aa)
THBS1Thrombospondin 1. (1171 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
GIPGastric inhibitory polypeptide. (153 aa)
EIF2B5Translation initiation factor eIF-2B subunit epsilon; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. (729 aa)
RBM4RNA-binding protein 4; RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation [...] (365 aa)
PRKAA2Non-specific serine/threonine protein kinase. (537 aa)
SLC12A6Solute carrier family 12 member 6. (1197 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (260 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (468 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1815 aa)
ZNF236Zinc finger protein 236. (1806 aa)
PDK3Protein-serine/threonine kinase. (439 aa)
ENSOCUP00000045925TGFb_propeptide domain-containing protein. (272 aa)
PPP3CASerine/threonine-protein phosphatase. (695 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (664 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
XBP1X-box binding protein 1. (208 aa)
CCDC186Coiled-coil domain containing 186. (925 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (844 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (700 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
SLC30A8Solute carrier family 30 member 8. (369 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (705 aa)
AQP4Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
GLULGlutamine synthetase. (373 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (226 aa)
FKBP1BPeptidyl-prolyl cis-trans isomerase FKBP1B; Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). (96 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
GIPRGastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (468 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1. (751 aa)
CYP7A1Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (By similarity). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis (Probable). Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha [...] (712 aa)
UCP2Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
PAX2Paired box 2. (448 aa)
NPTX1Neuronal pentraxin 1. (454 aa)
CLTRNCollectrin domain-containing protein. (251 aa)
UCN3Urocortin 3. (167 aa)
GCLMGlutamate-cysteine ligase modifier subunit. (388 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
PFKFB26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2. (519 aa)
IGF1RTyrosine-protein kinase receptor. (1464 aa)
SESN2Sestrin 2. (480 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
G1T8W0_RABITRESP18 domain-containing protein. (91 aa)
ANGPT2Angiopoietin 2. (496 aa)
SLC37A4Solute carrier family 37 member 4. (451 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
CPB2Carboxypeptidase B2. (424 aa)
G1TI49_RABITWD_REPEATS_REGION domain-containing protein. (223 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (361 aa)
AGERAdvanced glycosylation end-product specific receptor. (401 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in the pancreas and cardiovascular system. Contributes to the regulation of the action potential (AP) repolarization, duration and frequency of repetitive AP firing in neurons, muscle cells and endocrine cells and plays a role in homeostatic attenuation of electrical excitability throughout the brain. Plays also a role in the regulation of exocytosis independently of its electrical function. Forms [...] (858 aa)
RAB11FIP2RAB11 family interacting protein 2. (552 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
SELENOSUncharacterized protein. (317 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (996 aa)
PRLHProlactin releasing hormone. (87 aa)
RMI1RecQ mediated genome instability 1. (621 aa)
SIDT2SID1 transmembrane family member 2. (853 aa)
SARM1Sterile alpha and TIR motif containing 1. (703 aa)
ADIPOQC1q domain-containing protein. (244 aa)
ENSOCUP00000023367annotation not available (209 aa)
PTPRNProtein tyrosine phosphatase receptor type N. (979 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ZBTB20Zinc finger and BTB domain containing 20. (741 aa)
ICAM1Intercellular adhesion molecule 1. (534 aa)
SELENOTSelenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (194 aa)
PPARDUncharacterized protein. (420 aa)
TRA2BTransformer 2 beta homolog. (340 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (922 aa)
GCKPhosphotransferase. (246 aa)
SLC8A1J domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (852 aa)
SIN3ASIN3 transcription regulator family member A. (1241 aa)
TCF7L2Transcription factor 7 like 2. (605 aa)
LOC100357982BZIP domain-containing protein. (301 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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