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| | CCBE1 | Collagen and calcium binding EGF domains 1. (405 aa) |
| | ENSOCUP00000047950 | Uncharacterized protein. (143 aa) |
| | ANGPT1 | Angiopoietin 1. (551 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (483 aa) |
| | ENSOCUP00000046835 | Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (564 aa) |
| | CARD10 | Caspase recruitment domain family member 10. (1058 aa) |
| | ENSOCUP00000045925 | TGFb_propeptide domain-containing protein. (272 aa) |
| | LOC100356734 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1283 aa) |
| | ENSOCUP00000045718 | Uncharacterized protein. (312 aa) |
| | ENSOCUP00000045056 | PDZ domain-containing protein. (145 aa) |
| | ENSOCUP00000044478 | Uncharacterized protein. (599 aa) |
| | ENSOCUP00000044284 | TGFb_propeptide domain-containing protein. (260 aa) |
| | PTPRM | Protein tyrosine phosphatase receptor type M. (1549 aa) |
| | PLPP3 | acidPPc domain-containing protein. (331 aa) |
| | GRN | Granulin precursor. (626 aa) |
| | ENSOCUP00000041840 | TGFb_propeptide domain-containing protein. (219 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (823 aa) |
| | ENSOCUP00000041779 | Uncharacterized protein. (73 aa) |
| | ENSOCUP00000041711 | Uncharacterized protein. (157 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | CLASP1 | Cytoplasmic linker associated protein 1. (1512 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase. (511 aa) |
| | HIF1A | Uncharacterized protein. (851 aa) |
| | BCAS3 | BCAS3 microtubule associated cell migration factor. (923 aa) |
| | SPRED1 | Sprouty related EVH1 domain containing 1. (444 aa) |
| | ENSOCUP00000040382 | Uncharacterized protein. (1384 aa) |
| | JUN | BZIP domain-containing protein; Belongs to the bZIP family. (352 aa) |
| | ENSOCUP00000039880 | Uncharacterized protein. (140 aa) |
| | PTK2-2 | FERM_N_2 domain-containing protein. (121 aa) |
| | SEMA4A | Semaphorin 4A; Belongs to the semaphorin family. (977 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | MAP2K5 | Mitogen-activated protein kinase kinase 5. (551 aa) |
| | BCAR1 | BCAR1 scaffold protein, Cas family member. (869 aa) |
| | RHOB | Ras homolog family member B. (196 aa) |
| | ENSOCUP00000037329 | TGFb_propeptide domain-containing protein. (263 aa) |
| | SP1 | Sp1 transcription factor. (792 aa) |
| | MAP3K3 | Mitogen-activated protein kinase kinase kinase 3. (681 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1060 aa) |
| | MAP4K4 | Mitogen-activated protein kinase kinase kinase kinase 4. (1323 aa) |
| | ENSOCUP00000036131 | Uncharacterized protein. (140 aa) |
| | SASH1 | SAM and SH3 domain containing 1. (1246 aa) |
| | GLIPR2 | GLI pathogenesis related 2; Belongs to the CRISP family. (154 aa) |
| | ENPP2 | Ectonucleotide pyrophosphatase/phosphodiesterase 2. (939 aa) |
| | CD40 | Uncharacterized protein. (494 aa) |
| | SMOC2 | Uncharacterized protein. (1119 aa) |
| | FGF18 | Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (231 aa) |
| | GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (852 aa) |
| | MMRN2 | Multimerin 2. (925 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (873 aa) |
| | CTSH | Uncharacterized protein; Belongs to the peptidase C1 family. (601 aa) |
| | LOC103345451 | TGFb_propeptide domain-containing protein. (203 aa) |
| | PTPRG | Protein tyrosine phosphatase receptor type G. (1444 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | EMP2 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (259 aa) |
| | PTK2 | Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1041 aa) |
| | ENSOCUP00000029750 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (907 aa) |
| | SLIT2 | Slit guidance ligand 2. (1542 aa) |
| | ITGA2 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1202 aa) |
| | IQSEC1 | IQ motif and Sec7 domain 1. (1144 aa) |
| | PTN | Pleiotrophin. (242 aa) |
| | ENSOCUP00000028841 | Uncharacterized protein. (140 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (272 aa) |
| | ENSOCUP00000027724 | WH1 domain-containing protein. (155 aa) |
| | RAB11B | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] (312 aa) |
| | NFE2L2 | Nuclear factor, erythroid 2 like 2. (677 aa) |
| | BMPER | BMP binding endothelial regulator. (685 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1209 aa) |
| | G1U7S6_RABIT | Uncharacterized protein. (209 aa) |
| | G1U7N5_RABIT | PID domain-containing protein. (200 aa) |
| | PRKCA | Protein kinase C alpha type; Calcium-activated, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascades involving MAPK1/3 (ERK1/2) and RAP1GAP. Depending on the cell type, is involved in cell proliferation and cell growth arrest by positive and negative regul [...] (664 aa) |
| | HRG | Histidine-rich glycoprotein; Plasma glycoprotein that binds a number of ligands such as heme, heparin, heparan sulfate, thrombospondin, plasminogen, and divalent metal ions. Inhibits rosette formation. Acts as an adapter protein and implicated in regulating many processes such as immune complex and pathogen clearance, cell adhesion, angiogenesis, coagulation and fibrinolysis. Mediates clearance of necrotic cells through enhancing the phagocytosis of necrotic cells in a heparan sulfate-dependent pathway. This process can be regulated by the presence of certain HRG ligands such as hepari [...] (572 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (144 aa) |
| | MMP9 | Matrix metalloproteinase-9; Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity). (707 aa) |
| | ETS1 | Uncharacterized protein. (533 aa) |
| | ALOX12 | Arachidonate 12-lipoxygenase, 12S type. (663 aa) |
| | SYNJ2BP | PDZ domain-containing protein. (145 aa) |
| | ARSI | Arylsulfatase family member I. (571 aa) |
| | SIRT1 | Sirtuin 1. (748 aa) |
| | ANGPT4 | Angiopoietin 4. (487 aa) |
| | HAS2 | Uncharacterized protein. (556 aa) |
| | ROCK2 | Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1131 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (870 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa) |
| | CORO1C | Coronin; Belongs to the WD repeat coronin family. (525 aa) |
| | CXCL13 | C-X-C motif chemokine ligand 13. (105 aa) |
| | VIL1 | Villin 1. (813 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa) |
| | RREB1 | Ras responsive element binding protein 1. (1551 aa) |
| | MEOX2 | Mesenchyme homeobox 2. (303 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (996 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa) |
| | ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (334 aa) |
| | CIB1 | Uncharacterized protein. (143 aa) |
| | EPHA2 | EPH receptor A2. (1031 aa) |
| | G1TGC0_RABIT | Uncharacterized protein. (214 aa) |
| | ACVRL1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (327 aa) |
| | FGFBP1 | Fibroblast growth factor binding protein 1. (245 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa) |
| | ANXA3 | Annexin. (323 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | TEK | TEK receptor tyrosine kinase. (1025 aa) |
| | FUT1 | Galactoside 2-alpha-L-fucosyltransferase 1; Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Gal-beta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. Belongs to the glycosyltransferase 11 family. (373 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1198 aa) |
| | EPB41L4B | Erythrocyte membrane protein band 4.1 like 4B. (811 aa) |
| | MCC | MCC regulator of WNT signaling pathway. (1105 aa) |
| | RIN2 | Ras and Rab interactor 2. (895 aa) |
| | PDCD10 | Programmed cell death 10. (212 aa) |
| | ANGPT2 | Angiopoietin 2. (496 aa) |
| | G1T8C0_RABIT | Uncharacterized protein. (311 aa) |
| | HDAC9 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1068 aa) |
| | SVBP | Uncharacterized protein. (188 aa) |
| | JCAD | Junctional cadherin 5 associated. (1271 aa) |
| | DOCK5 | Dedicator of cytokinesis 5; Belongs to the DOCK family. (1853 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | TACSTD2 | Tumor associated calcium signal transducer 2. (327 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (744 aa) |
| | DAB2IP | DAB2 interacting protein. (1178 aa) |
| | GDF2 | Growth differentiation factor 2. (434 aa) |
| | ADGRA2 | Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1319 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2547 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | HSPB1 | Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (204 aa) |
| | SPARC | SPARC; Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity); Belongs to the SPARC family. (315 aa) |
| | PTPRR | Protein tyrosine phosphatase receptor type R. (657 aa) |
| | JUP | Junction plakoglobin. (745 aa) |
| | RTN4 | Reticulon. (1110 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (398 aa) |
| | NUS1 | NUS1 dehydrodolichyl diphosphate synthase subunit. (293 aa) |
| | SRPX2 | Sushi repeat containing protein X-linked 2. (465 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1390 aa) |
| | BMP4 | Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). (409 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (580 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa) |
| | HMOX1 | Heme oxygenase 1. (288 aa) |
| | ADAM17 | ADAM metallopeptidase domain 17. (827 aa) |
| | BMP10 | Bone morphogenetic protein 10. (428 aa) |
| | ITGA3 | Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1072 aa) |
| | VASH1 | Vasohibin 1. (369 aa) |
| | GLUL | Glutamine synthetase. (373 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | NF1 | Neurofibromin 1. (2841 aa) |
| | HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1115 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa) |
| | G1SV95_RABIT | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (780 aa) |
| | EPB41L5 | Erythrocyte membrane protein band 4.1 like 5. (731 aa) |
| | DUSP10 | Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | CAPN7 | Calpain 7; Belongs to the peptidase C2 family. (813 aa) |
| | FOXP1 | Fork-head domain-containing protein. (714 aa) |
| | PLK2 | Serine/threonine-protein kinase PLK. (666 aa) |
| | DCN | Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (360 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa) |
| | ATP5F1B | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa) |
| | NR2E1 | Uncharacterized protein. (475 aa) |
| | LGMN | Legumain. (435 aa) |
| | STC1 | Stanniocalcin 1. (247 aa) |
| | HYAL1 | Hyaluronidase. (497 aa) |
| | RHOJ | Ras homolog family member J. (214 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | KDR | Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | AMOT | Angiomotin. (1091 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (950 aa) |
| | KRIT1 | Uncharacterized protein. (736 aa) |
| | EFNA1 | Ephrin A1; Belongs to the ephrin family. (205 aa) |
| | ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa) |
| | THBS1 | Thrombospondin 1. (1171 aa) |
| | MAPRE2 | Microtubule associated protein RP/EB family member 2. (325 aa) |
| | ITGB1BP1 | PID domain-containing protein. (200 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1540 aa) |
| | ATOH8 | Atonal bHLH transcription factor 8. (369 aa) |
| | PTPN23 | Protein tyrosine phosphatase non-receptor type 23. (1630 aa) |
| | PATZ1 | POZ and AT hook containing zinc finger 1 long C isoform (Predicted). (687 aa) |
| | P2RX4 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (387 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1; Belongs to the protein kinase superfamily. (325 aa) |
| | ARF6 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | PPM1F | Protein phosphatase, Mg2+/Mn2+ dependent 1F. (446 aa) |
| | TACR1 | Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa) |
| | AGT | Angiotensinogen; Belongs to the serpin family. (477 aa) |
| | FGF2 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (155 aa) |
| | WNT5A | Protein Wnt-5a; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta- catenin-induced reporter gene expression (By similarity). Suppression of the canonical pathway allows chondrogenesis to occur. Inhibits tumor formation. Stimulates cell migration. Decrease [...] (380 aa) |
| | ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif 9. (2187 aa) |
| | SERPINF1 | Serpin family F member 1; Belongs to the serpin family. (418 aa) |
| | STARD13 | StAR related lipid transfer domain containing 13. (1201 aa) |
| | ARSJ | Sulfatase domain-containing protein. (149 aa) |
| | HDAC6 | Histone deacetylase 6. (1257 aa) |
| | MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (485 aa) |
