Your Input: | |
| | SRPX2 | Sushi repeat containing protein X-linked 2. (465 aa) |
| | ENSOCUP00000040382 | Uncharacterized protein. (1384 aa) |
| | JUN | BZIP domain-containing protein; Belongs to the bZIP family. (352 aa) |
| | ENSOCUP00000039880 | Uncharacterized protein. (140 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | BCAR1 | BCAR1 scaffold protein, Cas family member. (869 aa) |
| | RHOB | Ras homolog family member B. (196 aa) |
| | ENSOCUP00000037329 | TGFb_propeptide domain-containing protein. (263 aa) |
| | SP1 | Sp1 transcription factor. (792 aa) |
| | MAP3K3 | Mitogen-activated protein kinase kinase kinase 3. (681 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1060 aa) |
| | MAP4K4 | Mitogen-activated protein kinase kinase kinase kinase 4. (1323 aa) |
| | ENSOCUP00000036131 | Uncharacterized protein. (140 aa) |
| | SASH1 | SAM and SH3 domain containing 1. (1246 aa) |
| | GLIPR2 | GLI pathogenesis related 2; Belongs to the CRISP family. (154 aa) |
| | ENPP2 | Ectonucleotide pyrophosphatase/phosphodiesterase 2. (939 aa) |
| | CD40 | Uncharacterized protein. (494 aa) |
| | SMOC2 | Uncharacterized protein. (1119 aa) |
| | FGF18 | Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (231 aa) |
| | GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (852 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (873 aa) |
| | CTSH | Uncharacterized protein; Belongs to the peptidase C1 family. (601 aa) |
| | LOC103345451 | TGFb_propeptide domain-containing protein. (203 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | ITGA2 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1202 aa) |
| | IQSEC1 | IQ motif and Sec7 domain 1. (1144 aa) |
| | ENSOCUP00000028841 | Uncharacterized protein. (140 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (272 aa) |
| | RAB11B | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] (312 aa) |
| | NFE2L2 | Nuclear factor, erythroid 2 like 2. (677 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1209 aa) |
| | G1U7S6_RABIT | Uncharacterized protein. (209 aa) |
| | G1U7N5_RABIT | PID domain-containing protein. (200 aa) |
| | PRKCA | Protein kinase C alpha type; Calcium-activated, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascades involving MAPK1/3 (ERK1/2) and RAP1GAP. Depending on the cell type, is involved in cell proliferation and cell growth arrest by positive and negative regul [...] (664 aa) |
| | MMP9 | Matrix metalloproteinase-9; Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity). (707 aa) |
| | ETS1 | Uncharacterized protein. (533 aa) |
| | ALOX12 | Arachidonate 12-lipoxygenase, 12S type. (663 aa) |
| | SIRT1 | Sirtuin 1. (748 aa) |
| | ANGPT4 | Angiopoietin 4. (487 aa) |
| | HAS2 | Uncharacterized protein. (556 aa) |
| | ROCK2 | Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1131 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (870 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa) |
| | VIL1 | Villin 1. (813 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa) |
| | RREB1 | Ras responsive element binding protein 1. (1551 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (996 aa) |
| | ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (334 aa) |
| | CIB1 | Uncharacterized protein. (143 aa) |
| | FGFBP1 | Fibroblast growth factor binding protein 1. (245 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa) |
| | ANXA3 | Annexin. (323 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | TEK | TEK receptor tyrosine kinase. (1025 aa) |
| | FUT1 | Galactoside 2-alpha-L-fucosyltransferase 1; Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Gal-beta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. Belongs to the glycosyltransferase 11 family. (373 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1198 aa) |
| | EPB41L4B | Erythrocyte membrane protein band 4.1 like 4B. (811 aa) |
| | RIN2 | Ras and Rab interactor 2. (895 aa) |
| | JCAD | Junctional cadherin 5 associated. (1271 aa) |
| | DOCK5 | Dedicator of cytokinesis 5; Belongs to the DOCK family. (1853 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (744 aa) |
| | ADGRA2 | Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1319 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2547 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | HSPB1 | Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (204 aa) |
| | SPARC | SPARC; Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity); Belongs to the SPARC family. (315 aa) |
| | RTN4 | Reticulon. (1110 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (398 aa) |
| | NUS1 | NUS1 dehydrodolichyl diphosphate synthase subunit. (293 aa) |
| | BCAS3 | BCAS3 microtubule associated cell migration factor. (923 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1390 aa) |
| | BMP4 | Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). (409 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (580 aa) |
| | HMOX1 | Heme oxygenase 1. (288 aa) |
| | ADAM17 | ADAM metallopeptidase domain 17. (827 aa) |
| | ITGA3 | Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1072 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa) |
| | G1SV95_RABIT | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) |
| | EPB41L5 | Erythrocyte membrane protein band 4.1 like 5. (731 aa) |
| | CAPN7 | Calpain 7; Belongs to the peptidase C2 family. (813 aa) |
| | FOXP1 | Fork-head domain-containing protein. (714 aa) |
| | PLK2 | Serine/threonine-protein kinase PLK. (666 aa) |
| | ATP5F1B | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa) |
| | LGMN | Legumain. (435 aa) |
| | HYAL1 | Hyaluronidase. (497 aa) |
| | RHOJ | Ras homolog family member J. (214 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | KDR | Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | AMOT | Angiomotin. (1091 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (950 aa) |
| | ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa) |
| | THBS1 | Thrombospondin 1. (1171 aa) |
| | MAPRE2 | Microtubule associated protein RP/EB family member 2. (325 aa) |
| | ITGB1BP1 | PID domain-containing protein. (200 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1540 aa) |
| | ATOH8 | Atonal bHLH transcription factor 8. (369 aa) |
| | P2RX4 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (387 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1; Belongs to the protein kinase superfamily. (325 aa) |
| | ARF6 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | PPM1F | Protein phosphatase, Mg2+/Mn2+ dependent 1F. (446 aa) |
| | TACR1 | Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa) |
| | AGT | Angiotensinogen; Belongs to the serpin family. (477 aa) |
| | FGF2 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (155 aa) |
| | WNT5A | Protein Wnt-5a; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta- catenin-induced reporter gene expression (By similarity). Suppression of the canonical pathway allows chondrogenesis to occur. Inhibits tumor formation. Stimulates cell migration. Decrease [...] (380 aa) |
| | HDAC6 | Histone deacetylase 6. (1257 aa) |
| | CCBE1 | Collagen and calcium binding EGF domains 1. (405 aa) |
| | ENSOCUP00000047950 | Uncharacterized protein. (143 aa) |
| | ANGPT1 | Angiopoietin 1. (551 aa) |
| | ENSOCUP00000045925 | TGFb_propeptide domain-containing protein. (272 aa) |
| | ENSOCUP00000044284 | TGFb_propeptide domain-containing protein. (260 aa) |
| | PLPP3 | acidPPc domain-containing protein. (331 aa) |
| | GRN | Granulin precursor. (626 aa) |
| | ENSOCUP00000041840 | TGFb_propeptide domain-containing protein. (219 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (823 aa) |
| | ENSOCUP00000041779 | Uncharacterized protein. (73 aa) |
| | ENSOCUP00000041711 | Uncharacterized protein. (157 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | CLASP1 | Cytoplasmic linker associated protein 1. (1512 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase. (511 aa) |
| | HIF1A | Uncharacterized protein. (851 aa) |
