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| | SYNGAP1 | Synaptic Ras GTPase activating protein 1. (1337 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (557 aa) |
| | NPPC | Uncharacterized protein. (351 aa) |
| | ABCC8 | Uncharacterized protein. (1086 aa) |
| | TACSTD2 | Tumor associated calcium signal transducer 2. (327 aa) |
| | VAX1 | Ventral anterior homeobox 1. (310 aa) |
| | MELTF | Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family. (698 aa) |
| | ATOH1 | Atonal bHLH transcription factor 1. (359 aa) |
| | DYNLT1 | Dynein light chain Tctex-type 1. (113 aa) |
| | SEMA4D | Semaphorin 4D; Belongs to the semaphorin family. (864 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (138 aa) |
| | RTN4 | Reticulon. (1110 aa) |
| | SEMA3D | Semaphorin 3D; Belongs to the semaphorin family. (777 aa) |
| | SEMA3A | Semaphorin 3A; Belongs to the semaphorin family. (770 aa) |
| | SEMA3F | Semaphorin 3F; Belongs to the semaphorin family. (784 aa) |
| | SORL1 | Sortilin-related receptor; Sorting receptor that directs several proteins to their correct location within the cell. Along with AP-1 complex, involved Golgi apparatus - endosome sorting. Sorting receptor for APP, regulating its intracellular trafficking and processing into amyloidogenic-beta peptides. Retains APP in the trans-Golgi network, hence preventing its transit through late endosomes where amyloid beta peptides Abeta40 and Abeta42 are generated. May also sort newly produced amyloid-beta peptides to lysosomes for catabolism. Does not affect APP trafficking from the endoplasmic r [...] (2213 aa) |
| | FBLN1 | Fibulin 1. (457 aa) |
| | DICER1 | Uncharacterized protein. (821 aa) |
| | FRZB | Frizzled related protein. (318 aa) |
| | RUFY3 | RUN and FYVE domain containing 3. (617 aa) |
| | SYT4 | Synaptotagmin 4. (425 aa) |
| | TMEM98 | Transmembrane protein 98. (226 aa) |
| | RAPGEF2 | Rap guanine nucleotide exchange factor 2. (1659 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | NODAL | Nodal growth differentiation factor. (348 aa) |
| | NF1 | Neurofibromin 1. (2841 aa) |
| | G1SV95_RABIT | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (780 aa) |
| | SEMA3G | Semaphorin 3G; Belongs to the semaphorin family. (777 aa) |
| | LHX2 | LIM homeobox 2. (414 aa) |
| | THY1 | Thy-1 cell surface antigen. (161 aa) |
| | CTNNA1 | Catenin alpha-1; Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and [...] (993 aa) |
| | DUSP10 | Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | DLL3 | Delta like canonical Notch ligand 3. (605 aa) |
| | NPR2 | Guanylate cyclase. (1044 aa) |
| | SEMA5B | Semaphorin 5B. (1077 aa) |
| | LINGO1 | Leucine rich repeat and Ig domain containing 1. (693 aa) |
| | NR2E1 | Uncharacterized protein. (475 aa) |
| | DRAXIN | Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (337 aa) |
| | GORASP1 | Golgi reassembly stacking protein 1. (438 aa) |
| | NF2 | Neurofibromin 2. (626 aa) |
| | SEMA4F | Ssemaphorin 4F; Belongs to the semaphorin family. (721 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (950 aa) |
| | AP1AR | Adaptor related protein complex 1 associated regulatory protein. (302 aa) |
| | SEMA5A | Semaphorin 5A. (978 aa) |
| | TTPAL | Alpha tocopherol transfer protein like. (337 aa) |
| | FBN1 | Fibrillin 1. (2831 aa) |
| | ITGB1BP1 | PID domain-containing protein. (200 aa) |
| | DLX1 | Distal-less homeobox 1. (255 aa) |
| | SLIT1 | Slit guidance ligand 1. (1452 aa) |
| | SEMA4C | Semaphorin 4C; Belongs to the semaphorin family. (832 aa) |
| | SEMA4G | Semaphorin 4G; Belongs to the semaphorin family. (843 aa) |
| | SEMA6C | Sema domain-containing protein; Belongs to the semaphorin family. (948 aa) |
| | SEMA3B | Semaphorin 3B; Belongs to the semaphorin family. (757 aa) |
| | LRP4 | LDL receptor related protein 4. (1899 aa) |
| | DNAJB11 | J domain-containing protein. (373 aa) |
| | REST | RE1 silencing transcription factor. (930 aa) |
| | HOOK3 | Hook microtubule tethering protein 3. (1030 aa) |
| | BRINP1 | BMP/retinoic acid inducible neural specific 1. (761 aa) |
| | BCL11A | BAF chromatin remodeling complex subunit BCL11A. (975 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (391 aa) |
| | ARHGAP4 | Rho GTPase activating protein 4. (924 aa) |
| | RNF10 | Ring finger protein 10. (580 aa) |
| | KIAA0319 | KIAA0319. (1139 aa) |
| | WNT5A | Protein Wnt-5a; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta- catenin-induced reporter gene expression (By similarity). Suppression of the canonical pathway allows chondrogenesis to occur. Inhibits tumor formation. Stimulates cell migration. Decrease [...] (380 aa) |
| | LOC100357100 | CCHC-type domain-containing protein. (209 aa) |
| | PCM1 | Pericentriolar material 1. (2154 aa) |
| | TRIM46 | Tripartite motif containing 46. (907 aa) |
| | ULK2 | Unc-51 like autophagy activating kinase 2. (1066 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (400 aa) |
| | KIFAP3 | Kinesin associated protein 3. (793 aa) |
| | DPYSL5 | Dihydropyrimidinase like 5. (662 aa) |
| | FGF13 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (271 aa) |
| | ENSOCUP00000045925 | TGFb_propeptide domain-containing protein. (272 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (695 aa) |
| | DAB1 | DAB adaptor protein 1. (593 aa) |
| | ENSOCUP00000044284 | TGFb_propeptide domain-containing protein. (260 aa) |
| | RCC2 | Regulator of chromosome condensation 2. (509 aa) |
| | ENSOCUP00000043938 | Uncharacterized protein. (50 aa) |
| | TSPO | Uncharacterized protein. (516 aa) |
| | ENSOCUP00000041840 | TGFb_propeptide domain-containing protein. (219 aa) |
| | LOC100348748 | IGv domain-containing protein. (604 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | ENSOCUP00000041421 | CCHC-type domain-containing protein. (189 aa) |
| | RB1 | RB transcriptional corepressor 1. (943 aa) |
| | ENSOCUP00000040871 | Uncharacterized protein. (164 aa) |
| | SIRT2 | Sirtuin 2. (509 aa) |
| | ENSOCUP00000037873 | Uncharacterized protein. (411 aa) |
| | SEMA4A | Semaphorin 4A; Belongs to the semaphorin family. (977 aa) |
| | ENSOCUP00000037329 | TGFb_propeptide domain-containing protein. (263 aa) |
| | SEMA6A | Semaphorin 6A; Belongs to the semaphorin family. (1038 aa) |
| | YWHAH | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (309 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (666 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | DIP2B | Disco interacting protein 2 homolog B. (1621 aa) |
| | CTNNB1 | Catenin beta 1. (741 aa) |
| | LOC103345451 | TGFb_propeptide domain-containing protein. (203 aa) |
| | CLDN18 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa) |
| | MAP2 | Microtubule-associated protein. (1921 aa) |
| | SEMA7A | Sema domain-containing protein; Belongs to the semaphorin family. (408 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (933 aa) |
| | SHB | SH2 domain-containing protein. (607 aa) |
| | PTN | Pleiotrophin. (242 aa) |
| | CDKL3 | Cyclin dependent kinase like 3. (673 aa) |
| | DAAM2 | Dishevelled associated activator of morphogenesis 2. (1132 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (658 aa) |
| | TBX6 | T-box transcription factor 6. (488 aa) |
| | EFNB3 | Ephrin B3; Belongs to the ephrin family. (486 aa) |
| | GPR37L1 | G protein-coupled receptor 37 like 1. (537 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa) |
| | G1U940_RABIT | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (178 aa) |
| | ULK1 | Unc-51 like autophagy activating kinase 1. (1001 aa) |
| | DRD3 | Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (399 aa) |
| | G1U7N5_RABIT | PID domain-containing protein. (200 aa) |
| | ID1 | Inhibitor of DNA binding 1, HLH protein. (154 aa) |
| | FSTL4 | Follistatin like 4. (807 aa) |
| | WEE2 | Wee1-like protein kinase. (564 aa) |
| | ENSOCUP00000023367 | annotation not available (209 aa) |
| | CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) |
| | CERS2 | Ceramide synthase 2. (380 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) |
| | MAG | Uncharacterized protein. (58 aa) |
| | RFLNB | Refilin B. (214 aa) |
| | BMP7 | TGF_BETA_2 domain-containing protein. (170 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (279 aa) |
| | DMTN | Dematin actin binding protein. (424 aa) |
| | TRIM11 | Tripartite motif containing 11. (375 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (195 aa) |
| | PRTG | Ig-like domain-containing protein. (135 aa) |
| | RYK | Receptor like tyrosine kinase. (553 aa) |
| | MBD1 | Methyl-CpG binding domain protein 1. (631 aa) |
| | NKX6-1 | NK6 homeobox 1. (369 aa) |
| | PAX6 | Uncharacterized protein. (436 aa) |
| | CORO1C | Coronin; Belongs to the WD repeat coronin family. (525 aa) |
| | SPRY4 | Sprouty RTK signaling antagonist 4. (321 aa) |
| | KANK1 | KN motif and ankyrin repeat domains 1. (1387 aa) |
| | NTN1 | Netrin 1. (533 aa) |
| | G1TGC0_RABIT | Uncharacterized protein. (214 aa) |
| | LTF | Lactotransferrin; Belongs to the transferrin family. (708 aa) |
| | SOX11 | Transcription factor SOX. (446 aa) |
| | TNR | Tenascin R. (1359 aa) |
| | EDNRB | Endothelin receptor type B; Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRB sub-subfamily. (441 aa) |
| | SPART | Spartin. (679 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (120 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) |
| | PITX3 | Homeobox protein. (302 aa) |
| | RNF6 | Ring finger protein 6. (683 aa) |
| | S1PR3 | Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (367 aa) |
| | TLX2 | T cell leukemia homeobox 2. (284 aa) |
| | IFRD1 | Interferon related developmental regulator 1. (451 aa) |
| | SEMA4B | Semaphorin 4B; Belongs to the semaphorin family. (832 aa) |
