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| CD109 | CD109 molecule. (1318 aa) | ||||
| IL9 | Interleukin 9. (143 aa) | ||||
| RFFL | Ring finger and FYVE like domain containing E3 ubiquitin protein ligase. (361 aa) | ||||
| SERPINA5 | SERPIN domain-containing protein; Belongs to the serpin family. (572 aa) | ||||
| TIMP2 | Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor; Belongs to the protease inhibitor I35 (TIMP) family. (1218 aa) | ||||
| A2M | Alpha-2-macroglobulin. (1467 aa) | ||||
| ARL6IP1 | ADP ribosylation factor like GTPase 6 interacting protein 1. (203 aa) | ||||
| C5 | Complement C5. (1678 aa) | ||||
| LAMP3 | Uncharacterized protein. (427 aa) | ||||
| DHCR24 | 24-dehydrocholesterol reductase. (516 aa) | ||||
| SERPINB9 | Serpin family B member 9; Belongs to the serpin family. (376 aa) | ||||
| G1SN67_RABIT | SERPIN domain-containing protein; Belongs to the serpin family. (190 aa) | ||||
| SERPINB13 | SERPIN domain-containing protein; Belongs to the serpin family. (404 aa) | ||||
| ITIH6 | Inter-alpha-trypsin inhibitor heavy chain family member 6. (1320 aa) | ||||
| SERPINE2 | Serpin family E member 2; Belongs to the serpin family. (409 aa) | ||||
| PIH1D1 | PIH1 domain containing 1. (291 aa) | ||||
| THBS1 | Thrombospondin 1. (1171 aa) | ||||
| SPOCK3 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3. (344 aa) | ||||
| BIRC7 | Baculoviral IAP repeat containing 7. (278 aa) | ||||
| SERPINC1 | Serpin family C member 1; Belongs to the serpin family. (465 aa) | ||||
| LAMTOR5 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa) | ||||
| PRNP | Major prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (252 aa) | ||||
| CRIM1 | Cysteine rich transmembrane BMP regulator 1. (984 aa) | ||||
| WFDC9 | WAP four-disulfide core domain 9. (93 aa) | ||||
| FETUB | Fetuin B. (417 aa) | ||||
| AGT | Angiotensinogen; Belongs to the serpin family. (477 aa) | ||||
| WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (571 aa) | ||||
| SERPINF1 | Serpin family F member 1; Belongs to the serpin family. (418 aa) | ||||
| SERPINF2 | SERPIN domain-containing protein; Belongs to the serpin family. (533 aa) | ||||
| SERPING1 | Plasma protease C1 inhibitor; Belongs to the serpin family. (521 aa) | ||||
| ENSOCUP00000049392 | Uncharacterized protein. (134 aa) | ||||
| ITIH2 | Uncharacterized protein. (1030 aa) | ||||
| PSMF1 | Proteasome inhibitor subunit 1. (271 aa) | ||||
| G1SDV6_RABIT | Uncharacterized protein. (367 aa) | ||||
| ITIH3 | Inter-alpha-trypsin inhibitor heavy chain H3; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes; Belongs to the ITIH family. (880 aa) | ||||
| ANOS1 | Uncharacterized protein. (342 aa) | ||||
| TNFSF14 | TNF superfamily member 14. (241 aa) | ||||
| AVP | Uncharacterized protein. (285 aa) | ||||
| ENSOCUP00000045505 | Uncharacterized protein. (1102 aa) | ||||
| SERPINB6 | SERPIN domain-containing protein; Belongs to the serpin family. (606 aa) | ||||
| FAM124A | Family with sequence similarity 124 member A. (808 aa) | ||||
| ENSOCUP00000043881 | WAP domain-containing protein. (92 aa) | ||||
| WFDC2 | WAP four-disulfide core domain protein 2; Broad range protease inhibitor. (140 aa) | ||||
| FABP1 | FABP domain-containing protein. (194 aa) | ||||
| ENSOCUP00000043061 | Uncharacterized protein. (103 aa) | ||||
| PLAUR | Plasminogen activator, urokinase receptor. (365 aa) | ||||
| SPINT2 | Serine peptidase inhibitor, Kunitz type 2. (252 aa) | ||||
| DNAJA3 | Uncharacterized protein. (479 aa) | ||||
| SPINK7 | Serine peptidase inhibitor, Kazal type 7 (putative). (88 aa) | ||||
| DPEP1 | Dipeptidase 1; Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (524 aa) | ||||
| WFDC3 | Uncharacterized protein. (125 aa) | ||||
| SERPINA4 | SERPIN domain-containing protein; Belongs to the serpin family. (384 aa) | ||||
| ENSOCUP00000040784 | Uncharacterized protein. (227 aa) | ||||
| RPS6KA1 | Ribosomal protein S6 kinase. (813 aa) | ||||
| LOC100008810 | Uncharacterized protein. (154 aa) | ||||
| POR | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the N-terminal section; belongs to the flavodoxin family. (439 aa) | ||||
| SERPINA7 | Serpin family A member 7; Belongs to the serpin family. (466 aa) | ||||
| LOC100346690 | SERPIN domain-containing protein; Belongs to the serpin family. (422 aa) | ||||
| MICAL1 | Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1084 aa) | ||||
| PARK7 | Parkinsonism associated deglycase. (231 aa) | ||||
| GHRHR | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (524 aa) | ||||
| RPS6KA3 | Ribosomal protein S6 kinase. (751 aa) | ||||
| TNFAIP8 | Uncharacterized protein. (447 aa) | ||||
| ENSOCUP00000037812 | Uncharacterized protein. (1162 aa) | ||||
| MAP2K5 | Mitogen-activated protein kinase kinase 5. (551 aa) | ||||
| LOC100358221 | SERPIN domain-containing protein; Belongs to the serpin family. (419 aa) | ||||
| RECK | Uncharacterized protein. (993 aa) | ||||
| LOC100353846 | Uncharacterized protein. (1391 aa) | ||||
| ENSOCUP00000036340 | EGF-like domain-containing protein. (81 aa) | ||||
| ENSOCUP00000036017 | Uncharacterized protein. (176 aa) | ||||
| ENSOCUP00000035577 | Uncharacterized protein. (517 aa) | ||||
| LOC100348825 | Uncharacterized protein. (1436 aa) | ||||
| BIRC5 | Uncharacterized protein. (164 aa) | ||||
| KNG1 | Kininogen 1. (633 aa) | ||||
| ENSOCUP00000032248 | Cystatin domain-containing protein. (152 aa) | ||||
| RNF34 | Ring finger protein 34. (454 aa) | ||||
| ENSOCUP00000031431 | SERPIN domain-containing protein; Belongs to the serpin family. (120 aa) | ||||
| ENSOCUP00000031395 | Uncharacterized protein; Belongs to the serpin family. (216 aa) | ||||
| ENSOCUP00000030661 | Thioredoxin domain-containing protein. (183 aa) | ||||
| CST3 | Cystatin-C; This is a thiol proteinase inhibitor; Belongs to the cystatin family. (420 aa) | ||||
| SERPINE3 | Serpin family E member 3; Belongs to the serpin family. (435 aa) | ||||
| SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1. (466 aa) | ||||
| FURIN | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (666 aa) | ||||
| UBE2Z | Ubiquitin conjugating enzyme E2 Z. (291 aa) | ||||
| ENSOCUP00000028861 | SERPIN domain-containing protein; Belongs to the serpin family. (321 aa) | ||||
| APLP2 | Amyloid beta precursor like protein 2. (742 aa) | ||||
| XIAP | RING-type domain-containing protein. (633 aa) | ||||
| SPINK1 | Serine peptidase inhibitor, Kazal type 1. (89 aa) | ||||
| USP47 | Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1376 aa) | ||||
| LOC100352842 | Uncharacterized protein. (1442 aa) | ||||
| PRDX3 | Thioredoxin domain-containing protein. (307 aa) | ||||
| ENSOCUP00000027220 | Anaphylatoxin-like domain-containing protein. (74 aa) | ||||
| U3KNW9_RABIT | Kazal-like domain-containing protein. (106 aa) | ||||
| LOC103348521 | NTR domain-containing protein. (225 aa) | ||||
| LOC103348242 | Uncharacterized protein. (146 aa) | ||||
| AHSG | Alpha-2-HS-glycoprotein; A cell adhesion protein that binds immature cells of the granulocyte lineage; Belongs to the fetuin family. (338 aa) | ||||
| U3KMJ3_RABIT | SERPIN domain-containing protein; Belongs to the serpin family. (357 aa) | ||||
| SPINK9 | Putative Kazal type 13 serine peptidase inhibitor. (85 aa) | ||||
| RARRES1 | Retinoic acid receptor responder 1. (261 aa) | ||||
| G1U9F5_RABIT | WAP domain-containing protein. (53 aa) | ||||
| CSTA | Cystatin A; Belongs to the cystatin family. (99 aa) | ||||
| CST8 | Cystatin 8. (142 aa) | ||||
| G1U822_RABIT | SERPIN domain-containing protein; Belongs to the serpin family. (480 aa) | ||||
| SERPINB12 | SERPIN domain-containing protein; Belongs to the serpin family. (424 aa) | ||||
| CSTL1 | Cystatin like 1. (144 aa) | ||||
| WFDC10A | WAP four-disulfide core domain 10A. (80 aa) | ||||
| HRG | Histidine-rich glycoprotein; Plasma glycoprotein that binds a number of ligands such as heme, heparin, heparan sulfate, thrombospondin, plasminogen, and divalent metal ions. Inhibits rosette formation. Acts as an adapter protein and implicated in regulating many processes such as immune complex and pathogen clearance, cell adhesion, angiogenesis, coagulation and fibrinolysis. Mediates clearance of necrotic cells through enhancing the phagocytosis of necrotic cells in a heparan sulfate-dependent pathway. This process can be regulated by the presence of certain HRG ligands such as hepari [...] (572 aa) | ||||
| MMP9 | Matrix metalloproteinase-9; Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity). (707 aa) | ||||
| VTN | Vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. (475 aa) | ||||
| UBE2O | Ubiquitin conjugating enzyme E2 O. (1446 aa) | ||||
| G1U377_RABIT | Cystatin domain-containing protein. (149 aa) | ||||
| RENBP | Renin binding protein. (428 aa) | ||||
| SH3RF1 | SH3 domain containing ring finger 1. (896 aa) | ||||
| COL28A1 | Collagen type XXVIII alpha 1 chain. (1146 aa) | ||||
| LOC100350897 | Cystatin domain-containing protein. (141 aa) | ||||
| G1TYY7_RABIT | Cystatin domain-containing protein. (168 aa) | ||||
| LXN | Latexin. (222 aa) | ||||
| ITIH4 | Uncharacterized protein. (905 aa) | ||||
| NGF | Nerve growth factor. (157 aa) | ||||
| SERPINH1 | SERPIN domain-containing protein; Belongs to the serpin family. (201 aa) | ||||
| SPINK13 | Serine peptidase inhibitor, Kazal type 13 (putative). (94 aa) | ||||
| SIAH2 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (310 aa) | ||||
| RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1128 aa) | ||||
| VIL1 | Villin 1. (813 aa) | ||||
| CDKN2D | ANK_REP_REGION domain-containing protein. (310 aa) | ||||
| CST7 | Cystatin F. (164 aa) | ||||
| CSNK2A1 | Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoin [...] (391 aa) | ||||
| LOC100344662 | Uncharacterized protein. (469 aa) | ||||
| FNIP1 | Folliculin interacting protein 1. (1166 aa) | ||||
| G1TMP2_RABIT | Cystatin domain-containing protein. (145 aa) | ||||
| CSTB | Cystatin B; Belongs to the cystatin family. (77 aa) | ||||
| SERPINA3 | Serpin family A member 3; Belongs to the serpin family. (419 aa) | ||||
| G1TLX8_RABIT | RING-type domain-containing protein. (248 aa) | ||||
| WFDC5 | WAP four-disulfide core domain 5. (122 aa) | ||||
| WFDC11 | WAP four-disulfide core domain 11. (86 aa) | ||||
| SERPINA1 | Alpha-1-antiproteinase F; Inhibitor of serine proteases. The primary target is elastase, but also has a moderate affinity for plasmin and thrombin; Belongs to the serpin family. (458 aa) | ||||
| G1TG34_RABIT | WAP domain-containing protein. (75 aa) | ||||
| LTF | Lactotransferrin; Belongs to the transferrin family. (708 aa) | ||||
| P15A_RABIT | 15 kDa protein A; Binds to bacterial lipopolysaccharides (LPS), potentiates strongly the early antibacterial effects of BPI. Inhibits the late lethal action of BPI. (137 aa) | ||||
| SERPINI1 | Serpin family I member 1; Belongs to the serpin family. (493 aa) | ||||
| SERPINA12 | Serpin family A member 12; Belongs to the serpin family. (422 aa) | ||||
| ITIH5 | Inter-alpha-trypsin inhibitor heavy chain 5. (940 aa) | ||||
| SERPINB5 | Serpin family B member 5; Belongs to the serpin family. (375 aa) | ||||
| PTGS2 | Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...] (604 aa) | ||||
| UCHL5 | Ubiquitin carboxyl-terminal hydrolase. (609 aa) | ||||
| SFRP2 | Secreted frizzled related protein 2. (295 aa) | ||||
| SERPINA6 | Corticosteroid-binding globulin; Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species; Belongs to the serpin family. (451 aa) | ||||
| SERPINE1 | Serpin family E member 1; Belongs to the serpin family. (362 aa) | ||||
| TIMP4 | Metalloproteinase inhibitor 4; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor; Belongs to the protease inhibitor I35 (TIMP) family. (224 aa) | ||||
| CAAP1 | Caspase activity and apoptosis inhibitor 1. (356 aa) | ||||
| SPINT1 | Serine peptidase inhibitor, Kunitz type 1. (506 aa) | ||||
| LOC100356501 | Kazal-like domain-containing protein. (84 aa) | ||||
| BIN1 | Bridging integrator 1. (554 aa) | ||||
| SERPINB2 | Serine proteinase inhibitor, clade B, member 2 (Predicted); Belongs to the serpin family. (417 aa) | ||||
| SERPINB7 | Serine proteinase inhibitor, clade B, member 7 (Predicted); Belongs to the serpin family. (380 aa) | ||||
| NLE1 | Notchless homolog 1. (485 aa) | ||||
| WFDC8 | WAP four-disulfide core domain 8. (242 aa) | ||||
| LOC100353214 | Uncharacterized protein. (173 aa) | ||||
| A2ML1 | Alpha-2-macroglobulin like 1. (1451 aa) | ||||
| BIRC2 | Baculoviral IAP repeat containing 2. (601 aa) | ||||
| CRYAB | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions; Belongs to the small heat shock protein (HSP20) family. (175 aa) | ||||
| PAX2 | Paired box 2. (448 aa) | ||||
| SPINT4 | Serine peptidase inhibitor, Kunitz type 4. (101 aa) | ||||
| FAM124B | Family with sequence similarity 124 member B. (460 aa) | ||||
| NR4A1 | Nuclear receptor subfamily 4 group A member 1. (784 aa) | ||||
| IGBP1 | Uncharacterized protein. (339 aa) | ||||
| SORL1 | Sortilin-related receptor; Sorting receptor that directs several proteins to their correct location within the cell. Along with AP-1 complex, involved Golgi apparatus - endosome sorting. Sorting receptor for APP, regulating its intracellular trafficking and processing into amyloidogenic-beta peptides. Retains APP in the trans-Golgi network, hence preventing its transit through late endosomes where amyloid beta peptides Abeta40 and Abeta42 are generated. May also sort newly produced amyloid-beta peptides to lysosomes for catabolism. Does not affect APP trafficking from the endoplasmic r [...] (2213 aa) | ||||
| ITIH1 | Uncharacterized protein. (910 aa) | ||||
| TIMP1 | Metalloproteinase inhibitor 1; Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling (By similarity). (256 aa) | ||||
| PAPLN | Papilin, proteoglycan like sulfated glycoprotein. (1205 aa) | ||||
| BCL2L12 | BCL2 like 12. (267 aa) | ||||
| SERPINA9 | Serpin family A member 9; Belongs to the serpin family. (472 aa) | ||||
| APP | Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (769 aa) | ||||
| LOC100339150 | SERPIN domain-containing protein; Belongs to the serpin family. (390 aa) | ||||
| BIRC3 | Baculoviral IAP repeat containing 3. (591 aa) | ||||
| LOC100346672 | Uncharacterized protein. (1673 aa) | ||||
| NOL3 | Nucleolar protein 3. (212 aa) | ||||
| TRIAP1 | TP53 regulated inhibitor of apoptosis 1. (76 aa) | ||||
| SERPINI2 | Serpin family I member 2; Belongs to the serpin family. (405 aa) | ||||
| PCID2 | PCI domain containing 2. (486 aa) | ||||
| CSN2 | Beta-casein; Important role in determination of the surface properties of the casein micelles. (228 aa) | ||||
| SERPINB11 | SERPIN domain-containing protein; Belongs to the serpin family. (408 aa) | ||||
| SERPIND1 | Heparin cofactor 2; Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT). (480 aa) | ||||
| PCSK1N | Proprotein convertase subtilisin/kexin type 1 inhibitor. (260 aa) | ||||
| SPINK4 | Serine peptidase inhibitor, Kazal type 4. (86 aa) | ||||
| SPINK6 | Serine peptidase inhibitor, Kazal type 6. (80 aa) | ||||
| SPINK14 | Serine peptidase inhibitor, Kazal type 14 (putative). (96 aa) | ||||
| SPINK5 | Serine peptidase inhibitor, Kazal type 5. (1087 aa) | ||||
| ADORA2A | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (409 aa) | ||||
| WFDC13 | WAP four-disulfide core domain 13. (93 aa) | ||||
| PEBP1 | Hippocampal cholinergic neurostimulating peptide; Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation (By similarity). Belongs to the phosphatidylethanolamine-binding protein family. (187 aa) | ||||
| TIMP3 | Metalloproteinase inhibitor 3; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli (By similarity). (211 aa) | ||||
| TFPI | Tissue factor pathway inhibitor; Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. (300 aa) | ||||
| PAK2 | Serine/threonine-protein kinase PAK 2; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. Phosphorylates MAPK4 and MAPK6 and activates the downstream targ [...] (524 aa) | ||||
| CD27 | CD27 molecule. (260 aa) | ||||
| CAST | Erythrocyte calpastatin; Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue. (823 aa) | ||||
| SERPINB10 | SERPIN domain-containing protein; Belongs to the serpin family. (396 aa) | ||||
| C4A | Uncharacterized protein. (1743 aa) | ||||
| SERPINB8 | SERPIN domain-containing protein; Belongs to the serpin family. (374 aa) | ||||
| TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) | ||||
| BIRC6 | Baculoviral IAP repeat containing 6. (4863 aa) | ||||