(22 nodes) TBP-class protein binding network (Oryctolagus cuniculus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BTAF1	B-TFIID TATA-box binding protein associated factor 1. (1892 aa)
	TAF12	TATA-box binding protein associated factor 12. (161 aa)
	PSMC5	AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (598 aa)
	CAND1	Cullin associated and neddylation dissociated 1. (1207 aa)
	PSMC1	AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
	DR1	Down-regulator of transcription 1. (176 aa)
	GTF2A2	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
	BRF2	BRF2 RNA polymerase III transcription initiation factor subunit. (423 aa)
	BRF1	BRF1 RNA polymerase III transcription initiation factor subunit. (443 aa)
	U3KN18_RABIT	AAA domain-containing protein. (368 aa)
	ENSOCUP00000029087	AAA domain-containing protein; Belongs to the AAA ATPase family. (425 aa)
	ENSOCUP00000031335	TFIID_20kDa domain-containing protein. (217 aa)
	THRA	Thyroid hormone receptor alpha. (452 aa)
	RUVBL1	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (485 aa)
	TAF13	TATA-box binding protein associated factor 13. (124 aa)
	ENSOCUP00000038037	TFIIA_gamma_C domain-containing protein. (80 aa)
	DRAP1	CBFD_NFYB_HMF domain-containing protein. (362 aa)
	TAF1	Transcription initiation factor TFIID subunit. (1878 aa)
	YEATS2	YEATS domain containing 2. (1443 aa)
	RUVBL2	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
	CAND2	Cullin associated and neddylation dissociated 2 (putative). (1267 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRF1	BRF2	ENSOCUP00000013441	ENSOCUP00000011562	BRF1 RNA polymerase III transcription initiation factor subunit.	BRF2 RNA polymerase III transcription initiation factor subunit.	0.566
BRF2	BRF1	ENSOCUP00000011562	ENSOCUP00000013441	BRF2 RNA polymerase III transcription initiation factor subunit.	BRF1 RNA polymerase III transcription initiation factor subunit.	0.566
BTAF1	DR1	ENSOCUP00000042823	ENSOCUP00000006396	B-TFIID TATA-box binding protein associated factor 1.	Down-regulator of transcription 1.	0.875
BTAF1	DRAP1	ENSOCUP00000042823	ENSOCUP00000043259	B-TFIID TATA-box binding protein associated factor 1.	CBFD_NFYB_HMF domain-containing protein.	0.955
BTAF1	ENSOCUP00000031335	ENSOCUP00000042823	ENSOCUP00000031335	B-TFIID TATA-box binding protein associated factor 1.	TFIID_20kDa domain-containing protein.	0.411
BTAF1	TAF1	ENSOCUP00000042823	ENSOCUP00000045517	B-TFIID TATA-box binding protein associated factor 1.	Transcription initiation factor TFIID subunit.	0.652
BTAF1	TAF12	ENSOCUP00000042823	ENSOCUP00000003412	B-TFIID TATA-box binding protein associated factor 1.	TATA-box binding protein associated factor 12.	0.411
DR1	BTAF1	ENSOCUP00000006396	ENSOCUP00000042823	Down-regulator of transcription 1.	B-TFIID TATA-box binding protein associated factor 1.	0.875
DR1	DRAP1	ENSOCUP00000006396	ENSOCUP00000043259	Down-regulator of transcription 1.	CBFD_NFYB_HMF domain-containing protein.	0.998
DR1	ENSOCUP00000031335	ENSOCUP00000006396	ENSOCUP00000031335	Down-regulator of transcription 1.	TFIID_20kDa domain-containing protein.	0.416
DR1	TAF12	ENSOCUP00000006396	ENSOCUP00000003412	Down-regulator of transcription 1.	TATA-box binding protein associated factor 12.	0.439
DR1	YEATS2	ENSOCUP00000006396	ENSOCUP00000046068	Down-regulator of transcription 1.	YEATS domain containing 2.	0.904
DRAP1	BTAF1	ENSOCUP00000043259	ENSOCUP00000042823	CBFD_NFYB_HMF domain-containing protein.	B-TFIID TATA-box binding protein associated factor 1.	0.955
DRAP1	DR1	ENSOCUP00000043259	ENSOCUP00000006396	CBFD_NFYB_HMF domain-containing protein.	Down-regulator of transcription 1.	0.998
ENSOCUP00000029087	PSMC5	ENSOCUP00000029087	ENSOCUP00000003741	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.963
ENSOCUP00000029087	RUVBL1	ENSOCUP00000029087	ENSOCUP00000032883	AAA domain-containing protein; Belongs to the AAA ATPase family.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.456
ENSOCUP00000029087	U3KN18_RABIT	ENSOCUP00000029087	ENSOCUP00000026627	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein.	0.963
ENSOCUP00000031335	BTAF1	ENSOCUP00000031335	ENSOCUP00000042823	TFIID_20kDa domain-containing protein.	B-TFIID TATA-box binding protein associated factor 1.	0.411
ENSOCUP00000031335	DR1	ENSOCUP00000031335	ENSOCUP00000006396	TFIID_20kDa domain-containing protein.	Down-regulator of transcription 1.	0.416
ENSOCUP00000031335	ENSOCUP00000038037	ENSOCUP00000031335	ENSOCUP00000038037	TFIID_20kDa domain-containing protein.	TFIIA_gamma_C domain-containing protein.	0.744